Zobrazeno 1 - 10
of 81
pro vyhledávání: '"E Gautherot"'
Publikováno v:
The Journal of Immunology. 146:169-175
In order to target specifically double-Ag-positive cells in vivo, we synthesized chemically two mAb conjugates with specificities for both an allelic murine B cell-surface Ag and for a synthetic hapten. One conjugate was designed for its specificitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc17eb76afef1f061e9742adf8d92d0f
https://doi.org/10.4049/jimmunol.146.1.169
https://doi.org/10.4049/jimmunol.146.1.169
Autor:
J P, Vuillez, F, Kraeber-Bodéré, D, Moro, M, Bardiès, J Y, Douillard, E, Gautherot, E, Rouvier, J, Barbet, F, Garban, P, Moreau, J F, Chatal
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
As small cell lung carcinoma (SCLC) is frequently a widespread disease at diagnosis, highly radiosensitive and often only partially responsive to chemotherapy, radioimmunotherapy (RIT) would appear to be a promising technique for treatment. We report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90d6dabee3dd8d3c9c1222399fa44e25
https://pubmed.ncbi.nlm.nih.gov/10541373
https://pubmed.ncbi.nlm.nih.gov/10541373
Autor:
F, Kraeber-Bodéré, S, Bardet, C A, Hoefnagel, M R, Vieira, J P, Vuillez, A, Murat, T C, Ferreira, M, Bardiès, L, Ferrer, I, Resche, E, Gautherot, E, Rouvier, J, Barbet, J F, Chatal
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
The toxicity and therapeutic efficacy of escalating doses of anti-carcinoembryonic antigen x anti-N alpha-(diethylenetriamine-N,N,N',N''-tetraacetic acid)-In bispecific monoclonal antibody (F6-734) and iodine 131-labeled bivalent hapten were determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::566330fc838f5f5207ea9f592fe6e3ce
https://pubmed.ncbi.nlm.nih.gov/10541363
https://pubmed.ncbi.nlm.nih.gov/10541363
Autor:
M, Hosono, M N, Hosono, F, Kraeber-Bodéré, A, Devys, P, Thédrez, A, Faivre-Chauvet, E, Gautherot, J, Barbet, J F, Chatal
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 40(7)
The "affinity enhancement system," a two-step targeting technique using bispecific antibody and radiolabeled bivalent hapten, has been reported to be useful for carcinoembryonic antigen-expressing tumors. The purpose of this study was to evaluate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85da45814aabc85fec60e55bea133d5e
https://pubmed.ncbi.nlm.nih.gov/10405144
https://pubmed.ncbi.nlm.nih.gov/10405144
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(11)
Two-step pretargeting strategies have been designed to deliver radioisotopes to tumors more selectively than directly labeled antibodies or fragments. In this article, we compare quantitatively the potential of these strategies for the radioimmunothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46613a3309c8ab16099ff302bbb09f7f
https://pubmed.ncbi.nlm.nih.gov/9829586
https://pubmed.ncbi.nlm.nih.gov/9829586
Autor:
M, Hosono, M N, Hosono, F, Kraeber-Bodéré, A, Devys, P, Thédrez, M, Fiche, E, Gautherot, J, Barbet, J F, Chatal
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(9)
The purpose of this study was to evaluate biodistributions and absorbed doses of anti-carcinoembryonic antigen (CEA)/anti-diethylenetriamine pentaacetic acid (DTPA)-indium (anti-DTPA-In) bispecific monoclonal antibody (BsMAb) F6-734 and 125I-labeled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cca8b9ac54dd39a8ef81b0d7217af79
https://pubmed.ncbi.nlm.nih.gov/9744353
https://pubmed.ncbi.nlm.nih.gov/9744353
Publikováno v:
Cancer. 80
One of the main limitations of radioimmunotherapy (RIT) is the secondary toxicity related to the poor therapeutic indices achieved with labeled whole immunoglobulin (Ig)G or F(ab')2 fragments. To overcome this problem, we have developed a two-step ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50b645fcb0b56cd2440e9a160f3d1d54
https://pubmed.ncbi.nlm.nih.gov/9406716
https://pubmed.ncbi.nlm.nih.gov/9406716
Publikováno v:
Hormone research. 47(4-6)
The present article reviews the clinical trials that have been performed in recurrent medullary thyroid carcinoma patients with the Affinity Enhancement System. This technique uses bispecific antibodies to target radiolabelled bivalent haptens to tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6949734353d4e95421738262d49ec736
https://pubmed.ncbi.nlm.nih.gov/9167948
https://pubmed.ncbi.nlm.nih.gov/9167948
Autor:
M, Bardiès, S, Bardet, A, Faivre-Chauvet, P, Peltier, J Y, Douillard, M, Mahé, M, Fiche, A, Lisbona, F, Giacalone, P, Meyer, E, Gautherot, E, Rouvier, J, Barbet, J F, Chatal
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 37(11)
The purpose of this study was to estimate the dose delivered to tumor targets and normal tissues after two-step injection of an anti-CEA/anti-DTPA-In (F6-734) bispecific antibody and a 131I-labeled di-DTPA in-TL bivalent hapten in patients with medul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42fa750ada9b91bd0fc4888119bd0466
https://pubmed.ncbi.nlm.nih.gov/8917192
https://pubmed.ncbi.nlm.nih.gov/8917192
Publikováno v:
Journal of interferon research. 14(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a1e97ef93ddb26ff6a93d21446f458
https://pubmed.ncbi.nlm.nih.gov/7861038
https://pubmed.ncbi.nlm.nih.gov/7861038