Zobrazeno 1 - 10
of 162
pro vyhledávání: '"E Gabriela, Chiorean"'
Autor:
E. Gabriela Chiorean, Vincent Picozzi, Chung‐Pin Li, Marc Peeters, Joan Maurel, Jaswinder Singh, Talia Golan, Jean‐Frédéric Blanc, Sonya C. Chapman, Anwar M. Hussain, Erica L. Johnston, Howard S. Hochster
Publikováno v:
Cancer Medicine, Vol 12, Iss 20, Pp 20353-20364 (2023)
Abstract Background Pancreatic ductal adenocarcinomas (PDAC) are characterized by frequent cell cycle pathways aberrations. This study evaluated safety and efficacy of abemaciclib, a cyclin‐dependent kinase 4 and 6 inhibitor, as monotherapy or in c
Externí odkaz:
https://doaj.org/article/361cb4c885cb4edb9ee2ff88993a88f9
Autor:
David B. Zhen, Rachael A. Safyan, Eric Q. Konick, Ryan Nguyen, Colin C. Prichard, E. Gabriela Chiorean
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
Pancreatic ductal adenocarcinoma (PDA) is highly aggressive and has few treatment options. To personalize therapy, it is critical to delineate molecular subtypes and understand inter- and intra-tumoral heterogeneity. Germline testing for hereditary g
Externí odkaz:
https://doaj.org/article/fb652e64f16d4f0a91f3368c72bba34c
Autor:
Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John J. Nemunaitis, Dennis Kee, Avik Shome, Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar A. Grénman, Laura Caporiccio, Trevor D. McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan K. Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin G. Print, William R. Wilson, Michael A. Curran, Francis W. Hunter
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/b8265d5c0ed44e2583f6823d2b9a7cc0
Autor:
E. Gabriela Chiorean, Govind Nandakumar, Temidayo Fadelu, Sarah Temin, Ashley Efrain Alarcon-Rozas, Suyapa Bejarano, Adina-Emilia Croitoru, Surbhi Grover, Pritesh V. Lohar, Andrew Odhiambo, Se Hoon Park, Erika Ruiz Garcia, Catherine Teh, Azmina Rose, Bassem Zaki, Mary D. Chamberlin
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 414-438 (2020)
PURPOSETo provide expert guidance to clinicians and policymakers in resource-constrained settings on the management of patients with late-stage colorectal cancer.METHODSASCO convened a multidisciplinary, multinational Expert Panel that reviewed exist
Externí odkaz:
https://doaj.org/article/5cb5a49caa144bd8be0e87acef504fc8
Autor:
Jason J. Luke, Marwan Fakih, Charles Schneider, E. Gabriela Chiorean, Johanna Bendell, Rebecca Kristeleit, Razelle Kurzrock, Sarah P. Blagden, Irene Brana, Laura W. Goff, Kevin O’Hayer, Ryan Geschwindt, Michael Smith, Feng Zhou, Aung Naing
Publikováno v:
Scientia
Background Indoleamine 2,3-dioxygenase 1 (IDO1), an interferon-inducible enzyme, contributes to tumor immune intolerance. Immune checkpoint inhibition may increase interferon levels; combining IDO1 inhibition with immune checkpoint blockade represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a86bc969a7907b279383b86ec75a315
https://hdl.handle.net/11351/9837
https://hdl.handle.net/11351/9837
Autor:
Jingwu Xie, E. Gabriela Chiorean, Harlan E. Shannon, Marc S. Mendonca, Helmut Hanenberg, Helen Chin-Sinex, Xiaoli Zhang, Gloria H. Su, Hailan Liu, Dongsheng Gu
PDF file - 372K, Supplementary Figure 1 (Fig.S1)- Detection of CD24 transcript in AsPC1 cells, Supplementary Figure 2 (Fig.S2) Detection of Hh target genes in orthotopic pancreatic cancer models, Supplementary Figure 3 (Fig.S3) Expression of SHH and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf5c1591b2102ea48c026d3134b63de
https://doi.org/10.1158/1535-7163.22499871
https://doi.org/10.1158/1535-7163.22499871
Autor:
Jingwu Xie, E. Gabriela Chiorean, Harlan E. Shannon, Marc S. Mendonca, Helmut Hanenberg, Helen Chin-Sinex, Xiaoli Zhang, Gloria H. Su, Hailan Liu, Dongsheng Gu
PDF file - 94K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c4755e60c593c15139b1a1fb5eb5f1
https://doi.org/10.1158/1535-7163.22499874
https://doi.org/10.1158/1535-7163.22499874
Autor:
Jingwu Xie, E. Gabriela Chiorean, Harlan E. Shannon, Marc S. Mendonca, Helmut Hanenberg, Helen Chin-Sinex, Xiaoli Zhang, Gloria H. Su, Hailan Liu, Dongsheng Gu
Pancreatic cancer often presents in advanced stages and is unresponsive to conventional treatments. Thus, the need to develop novel treatment strategies for pancreatic cancer has never been greater. Here, we report that combination of focal irradiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff204e13a9f781050f93f9e5c9037c5c
https://doi.org/10.1158/1535-7163.c.6536292
https://doi.org/10.1158/1535-7163.c.6536292
Publikováno v:
Hepatobiliary Surgery and Nutrition. 11:115-118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc0081170685e7684b48181388cb1472
https://doi.org/10.21037/hbsn-2021-26
https://doi.org/10.21037/hbsn-2021-26
Autor:
Peter J. O'Dwyer, Teng Jin Ong, Chrystal U. Louis, Larry Lyons, Sibabrata Banerjee, Rafia Bhore, Daniel W. Pierce, David J. Reiss, Thomas Lila, Hatem H. Soliman, Daniel Ricardo Carrizosa, Rishi Jain, Aparna Parikh, Martin Guiterrez, David M. Waterhouse, E. Gabriela Chiorean, Aparna Kaylan, Ben George, Edward J. Kim, Howard S. Hochster, Zev A. Wainberg
Baseline (screening) vs treatment cycle 2 (P=.06; paired t test). For patient 5, baseline data were not available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd98b63eb49f579d01cbe44a0a85231
https://doi.org/10.1158/1078-0432.22475423
https://doi.org/10.1158/1078-0432.22475423