Zobrazeno 1 - 10
of 56
pro vyhledávání: '"E G Neilson"'
Publikováno v:
The Journal of Immunology. 152:1182-1189
RANTES is a member of the C-C subfamily of chemokines that functions as a proinflammatory chemoattractant for CD4+ T cells, monocytes, and eosinophils, and as an activator of basophils to release histamine. Like other members of the chemokine superfa
Publikováno v:
The Journal of Immunology. 150:867-879
The autoimmune B cell repertoire in anti-tubular basement membrane (alpha TBM) disease is focused on the nephritogenic P1 domain of the 3M-1 target Ag in kidney and normally expresses a disease-modifying cross-reactive Id (IdX). The molecular structu
Publikováno v:
The Journal of Immunology. 144:75-83
The experiments presented in this report describe the biochemical and functional characteristics of a soluble Th cell factor (ThF) which can induce a nephritogenic effector T cell repertoire producing autoimmune interstitial nephritis. The ThF is Ag-
Autor:
R, Kalluri, A, Torre, C F, Shield, E D, Zamborsky, M C, Werner, E, Suchin, G, Wolf, U M, Helmchen, L P, van den Heuvel, R, Grossman, S, Aradhye, E G, Neilson
Publikováno v:
Transplantation. 69(4)
Alport syndrome is a hereditary disorder of basement membranes especially affecting the kidneys, ears, and eyes. Some patients who undergo renal transplantation lose their kidneys as a result of posttransplant anti-glomerular basement membrane (anti-
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 45(2)
Members of the bcl-2 family of proteins regulate the occurrence of apoptotic cell death. Apoptosis is a feature of both acute and chronic renal diseases. Diabetes mellitus modulates renal growth; it induces acute tubuloepithelial cell hypertrophy, le
Publikováno v:
Experimental nephrology. 4(5)
Publikováno v:
The Journal of biological chemistry. 271(15)
The family of type IV collagen comprises six chains numbered alpha1 through alpha6. The alpha3(IV) NC1 domain is the primary target antigen for autoantibodies from patients with anti-basement membrane disease and Goodpasture syndrome. Earlier peptide
Publikováno v:
Proceedings of the Association of American Physicians. 108(2)
Goodpasture syndrome is an often fatal autoimmune disease associated with glomerulonephritis and/or pulmonary hemorrhage. The clinical manifestations of this disease correlate well with the presence of circulating antiglomerular basement membrane (GB
Publikováno v:
Contributions to nephrology. 118
Autor:
G, Wolf, E G, Neilson
Publikováno v:
Experimental nephrology. 4
Since the discovery of renin, almost 100 years ago, all the components of the renin-angiotensin system have been characterized on a molecular level. Angiotensin II (Ang II) receptors can be grouped in two classes: AT1 and AT2 receptors. In addition t