Zobrazeno 1 - 10
of 18
pro vyhledávání: '"E G Nabel"'
Publikováno v:
Methods in molecular medicine. 7
Despite considerable progress in the understanding of the molecular basis of cancer, many malignancies remain resistant to traditional forms of treatment. Certain cancers, such as melanoma or renal cell carcinoma, respond to modulation of immune func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::122242522aedffc2358deda66c7bd855
https://pubmed.ncbi.nlm.nih.gov/24493435
https://pubmed.ncbi.nlm.nih.gov/24493435
Publikováno v:
Methods in molecular medicine. 7
Cationic liposomes are preparations of positively charged lipids used for transfection of mammalian cells in vitro and in vivo. Although viruses efficiently infect mammalian cells, the potential risks of viral gene delivery spurred research in the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9acd60c8991c68e665665d9b0315961
https://pubmed.ncbi.nlm.nih.gov/24493422
https://pubmed.ncbi.nlm.nih.gov/24493422
Publikováno v:
Molecular and Cellular Biology. 14:7695-7703
NF-kappa B is an inducible transcription factor complex which regulates the expression of a variety of genes which are involved in the immune, inflammatory, and acute-phase responses. The maintenance of NF-kappa B activity in stimulated cells require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df040a3a8987108f40f6a987c869eb79
https://doi.org/10.1128/mcb.14.12.7695
https://doi.org/10.1128/mcb.14.12.7695
Publikováno v:
Nature medicine. 6(8)
Here we defined the main viral determinant of Ebola virus pathogenicity; synthesis of the virion glycoprotein (GP) of Ebola virus Zaire induced cytotoxic effects in human endothelial cells in vitro and in vivo. This effect mapped to a serine-threonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93b6a09764b964d535be5b422c54ad50
https://pubmed.ncbi.nlm.nih.gov/10932225
https://pubmed.ncbi.nlm.nih.gov/10932225
Publikováno v:
Blood. 95(2)
Occlusive thrombosis depends on the net balance between platelets, coagulation, and fibrinolytic factors. Epidemiologic information suggests that plasminogen activator inhibitor-1 (PAI-1), a central regulator of the fibrinolytic system, plays an impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39108c2ff3c89dd0f4d21a528c5e7605
https://pubmed.ncbi.nlm.nih.gov/10627465
https://pubmed.ncbi.nlm.nih.gov/10627465
Autor:
H J, Duckers, E G, Nabel
Publikováno v:
Seminars in interventional cardiology : SIIC. 3(3-4)
Recent studies show that the cyclin dependent kinase inhibitor KIP/CIP family members function as regulators of VSMC proliferation. The prevention and treatment of cell proliferation in arteries after percutaneous intervention, represents an attracti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0acb83dd9b4adc9f734d37bf44b0417a
https://pubmed.ncbi.nlm.nih.gov/10406694
https://pubmed.ncbi.nlm.nih.gov/10406694
Publikováno v:
Archives des maladies du coeur et des vaisseaux. 90(8)
Gene delivery to the kidney has both experimental and therapeutic potential in hypertension, although the delivery methods, distribution of transgene and subsequent inflammatory response have been poorly characterized. In adult male Sprague-Dawley ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9eaa86b4b545e593c21012da7858cc8f
https://pubmed.ncbi.nlm.nih.gov/9404421
https://pubmed.ncbi.nlm.nih.gov/9404421
Autor:
R D, Simari, E G, Nabel
Publikováno v:
Seminars in interventional cardiology : SIIC. 1(1)
Vascular gene transfer is the introduction of foreign DNA into host cells within the vessel wall. Expression of recombinant genes within vascular cells has been demonstrated in normal, injured and atherosclerotic arteries. Transfer of genes with biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0111a31b871b0a25ad97409a30a54539
https://pubmed.ncbi.nlm.nih.gov/9552497
https://pubmed.ncbi.nlm.nih.gov/9552497
Autor:
E G, Nabel
Publikováno v:
Atherosclerosis.
Arterial injury induces the synthesis of gene products that stimulate smooth muscle cell (SMC) migration and proliferation, leading to intimal hyperplasia. This process contributes to the pathogenesis of many cardiovascular diseases, including vascul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d888a6eb7a0dcf1bc79d2a661bf22d4
https://pubmed.ncbi.nlm.nih.gov/8821465
https://pubmed.ncbi.nlm.nih.gov/8821465
Autor:
G J, Nabel, A E, Chang, E G, Nabel, G E, Plautz, W, Ensminger, B A, Fox, P, Felgner, S, Shu, K, Cho
Publikováno v:
Human gene therapy. 5(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8309b083893ae07b2fba3f8d735cf36
https://pubmed.ncbi.nlm.nih.gov/8155772
https://pubmed.ncbi.nlm.nih.gov/8155772