Zobrazeno 1 - 10
of 12
pro vyhledávání: '"E G Hoal-van Helden"'
Publikováno v:
Cell Biology International. 25:71-81
The microbicidal capacity of the macrophage is frequently evaded by mycobacteria, leading to tuberculosis (TB). We investigated a number of parameters affecting the rate of growth of mycobacteria in human monocyte-derived macrophages (MDM). The resul
Publikováno v:
British Journal of Cancer
The establishment of a new prostate cell line (BM1604) from a human prostatic adenocarcinoma is reported. The line was rapidly established by culture of tissue on an extracellular matrix, previously laid down by culture of non-related cells. The meth
Autor:
R. Grundlingh, A. Harington, E G Hoal-van Helden, William R. Bourn, P. D. van Helden, Ian Wiid, Graeme Bradley
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 82(2-3)
Setting : DNA repair genes assist the organism in maintaining DNA integrity in the face of environmental (mutagenic) stress. The genome sequences of M. tuberculosis and M. bovis demonstrate sequences suggestive of an O 6 -alkylguanine-DNA alkyltransf
Publikováno v:
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 91(11)
Peak expiratory flow (PEF) is a useful measure of pulmonary health status and is frequently utilised in asthma management. Reduction in PEF is usually indicative of onset of asthma symptoms. However, use can be made of PEF values only if normal value
Publikováno v:
Cell biology international. 25(1)
Macrophages are an important component in the first line of defence of the innate immune system. They are capable of producing cytokines in response to bacterial challenge, as well as in response to cytokine stimuli from other cells in the immune sys
Publikováno v:
Carcinogenesis. 15(10)
We describe an improved, rapid and cost effective assay for measuring O6-alkylguanine-DNA alkyltransferase (AGT) levels in large numbers of small biological samples. The assay is based on the use of a synthetic O6-methylguanine oligonucleotide bound
Publikováno v:
The Lancet. 356:S61
Diagnosis and treatment P of individual patients with tuberculosis may not differ substantially between more-developed and less-developed countries. However, the differences in case-load, resources, and management result in a huge divide between the
Publikováno v:
British Journal of Cancer
Permanent cell lines (UCT-Mel 1 through 7) were established from biopsies of metastatic tissue taken from seven patients with malignant melanoma. Cells from these lines were all aneuploid and all grew as non-contact-inhibited, adherent monolayers. Al
Publikováno v:
Clinical and experimental immunology. 69(2)
A simple, rapid assay for measuring anti-DNA titre of serum which includes anti-Z-DNA is described. The assay involves solution binding of antibody to labelled DNA under conditions such that the DNA is altered to form a left-handed or Z-DNA structure
Publikováno v:
Cancer research. 48(20)
DNA "fingerprint" analysis has recently become known as a valuable technique for positive identification of any given individual. The chances for mistaken identity have been estimated to be 10(-6) for close siblings or as little as 10(-23) for random