Zobrazeno 1 - 10
of 12
pro vyhledávání: '"E G, Pamer"'
Publikováno v:
The Journal of Immunology. 158:3366-3371
Protective immunity to infection by intracellular pathogens begins with expansion of Ag-specific, effector T lymphocytes and is followed by persistence of pathogen-specific memory T cells. Infection by Listeria monocytogenes, an intracellular bacteri
Publikováno v:
The Journal of Immunology. 154:4642-4650
The ability of Listeria monocytogenes to gain access to the cytoplasm of infected cells results in the processing and presentation of bacterial Ags through the MHC class I pathway. As a result, CD8 T cells are the most effective mediators of acquired
Autor:
E G Pamer
Publikováno v:
The Journal of Immunology. 152:686-694
Murine infection with the intracellular bacterium Listeria monocytogenes elicits MHC class I-restricted CTL with specificity for multiple bacterial peptides. The variety and relative abundance of self-peptides bound by MHC molecules make identificati
Autor:
G, Lauvau, E G, Pamer
Publikováno v:
The Journal of Experimental Medicine
Major histocompatibility complex (MHC) class I–restricted CD8+ T cells play a critical role in the protective immunity against Mycobacterium tuberculosis (Mtb). However, only a few Mtb peptides recognized by MHC class Ia–restricted CD8+ T cells h
Autor:
T, Yajima, H, Nishimura, R, Ishimitsu, K, Yamamura, T, Watase, D H, Busch, E G, Pamer, H, Kuwano, Y, Yoshikai
Publikováno v:
European journal of immunology. 31(3)
We recently constructed IL-15 transgenic (Tg) mice using cDNA encoding a secretable isoform of the IL-15 precursor protein under the control of an MHC class I promoter. The IL-15 Tg mice exhibited resistance against a primary infection with Listeria
Autor:
N A, Marshall, J G, Howe, R, Formica, D, Krause, J E, Wagner, N, Berliner, J, Crouch, I, Pilip, D, Cooper, B R, Blazar, S, Seropian, E G, Pamer
Publikováno v:
Blood. 96(8)
Epstein-Barr virus (EBV)-specific CD8 T lymphocytes are present at remarkably high frequencies in healthy EBV(+) individuals and provide protection from EBV-associated lymphoproliferative diseases. Allogeneic peripheral blood stem cell transplantatio
Autor:
D H, Busch, E G, Pamer
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(9)
Infection of BALB/c mice with Listeria monocytogenes primes CD8+ cytotoxic T cells specific for four different H2-Kd-restricted peptides. In vitro restimulation of L. monocytogenes immune splenocytes with each of these peptides resulted in larger T c
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(8)
T lymphocytes eradicate and provide long-term immunity to infections caused by intracellular pathogens. The mechanisms that determine in vivo T cell response sizes are poorly understood. Although it is speculated that the relative processing efficien
Publikováno v:
The Journal of biological chemistry. 272(31)
Cytosolic antigen degradation is an initial step in the generation of major histocompatibility complex (MHC) class I-associated cytolytic T lymphocyte epitopes. Intracellular Listeria monocytogenes secretes p60, a murein hydrolase, into the host cell
Autor:
S, Vijh, E G, Pamer
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(7)
Protective immunity to infection by intracellular pathogens begins with expansion of Ag-specific, effector T lymphocytes and is followed by persistence of pathogen-specific memory T cells. Infection by Listeria monocytogenes, an intracellular bacteri