Zobrazeno 1 - 10
of 122
pro vyhledávání: '"E G, Engleman"'
Publikováno v:
The Journal of Immunology. 159:3113-3117
Prostatic acid phosphatase (PAP) is uniquely expressed in prostatic tissue and prostate cancer. In this study, the immunogenicity of PAP was investigated in a male rat model. We show that immunization with recombinant rat or human PAP in CFA leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54d7acf26c13f18d4e8300a03c67bcaa
https://doi.org/10.4049/jimmunol.159.7.3113
https://doi.org/10.4049/jimmunol.159.7.3113
Publikováno v:
The Journal of Immunology. 159:1115-1124
Previous studies have demonstrated that a mAb that recognizes the leukocyte surface Ag V7 inhibits TCR/CD3-dependent T cell activation. In the current study, we demonstrate that in addition to inhibiting T cell proliferation and IL-2 production, anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd5511753850aea82bc538b1b1aea2b
https://doi.org/10.4049/jimmunol.159.3.1115
https://doi.org/10.4049/jimmunol.159.3.1115
Publikováno v:
The Journal of Immunology. 158:2134-2142
Dendritic cells (DC) are potent APC that, in mature form, can be distinguished from other mononuclear cells on the basis of their distinct morphology, absence of lineage markers, and dense expression of MHC and costimulatory molecules. While comparin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb00f01c97c614bfcf05fc5f06315fcb
https://doi.org/10.4049/jimmunol.158.5.2134
https://doi.org/10.4049/jimmunol.158.5.2134
Publikováno v:
The Journal of Immunology. 157:72-80
We subjected PBMC of normal adults to density fractionation to enrich for an immunoblast fraction that would include early immune lineage precursors. Differential display PCR experiments identified one transcript that is expressed specifically in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::295bd240756496b585f98b553e5017a6
https://doi.org/10.4049/jimmunol.157.1.72
https://doi.org/10.4049/jimmunol.157.1.72
Autor:
F J Kos, E G Engleman
Publikováno v:
The Journal of Immunology. 155:578-584
Cell-mediated immunity involves the participation of both regulatory and cytotoxic cells. The conversion of precursors to effector CD8+ cytotoxic T (Tc) cells requires cell-cell collaboration in which CD4+ T cells are traditionally viewed as helper c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ec7b38afb5bafa9671f528fa114df6
https://doi.org/10.4049/jimmunol.155.2.578
https://doi.org/10.4049/jimmunol.155.2.578
Publikováno v:
The Journal of Immunology. 154:4434-4443
V7 is a cell surface glycoprotein expressed on Ag-activated T cells, monocytes, and granulocytes, as well as subpopulations of T cells and accessory cells present in thymic medulla and tonsil. A mAb directed against V7 inhibits the proliferative resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f58048bbff1e5025c0995f279a464f7b
https://doi.org/10.4049/jimmunol.154.9.4434
https://doi.org/10.4049/jimmunol.154.9.4434
Publikováno v:
The Journal of Immunology. 154:4423-4433
Among a panel of mouse mAbs generated to a human T cell clone, one mAb, V7.1, inhibited T cell activation in the mixed lymphocyte reaction and was studied further. V7.1 reacted strongly with Ag-specific T cell clones, in addition to freshly isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630ed1e02fb72339a8dcc2539440d5bf
https://doi.org/10.4049/jimmunol.154.9.4423
https://doi.org/10.4049/jimmunol.154.9.4423
Publikováno v:
The Journal of Immunology. 145:470-476
The vast majority of circulating lymphocytes that express the alpha,beta TCR in association with CD3 also express either CD4 or CD8 molecules, which are thought to act as important accessory structures in HLA class II- and I-restricted T cell functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51a0184898399e776db77e2174949a7
https://doi.org/10.4049/jimmunol.145.2.470
https://doi.org/10.4049/jimmunol.145.2.470
Autor:
S Markowicz, E G Engleman
Publikováno v:
Journal of Clinical Investigation. 85:955-961
Interest in human dendritic cells (DC) has been heightened recently by the discovery that this cell type is a primary target of the human immunodeficiency virus, the causative agent of AIDS. DC are bone marrow-derived cells with an extraordinarily po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85eb5d9bfb8b3cb75ecd840466eac84
https://doi.org/10.1172/jci114525
https://doi.org/10.1172/jci114525
Autor:
J Koide, E G Engleman
Publikováno v:
The Journal of Immunology. 144:32-40
We have previously demonstrated that fresh CD8+ T cells proliferate in response to autologous, alloantigen-primed CD4+ T cells, and differentiate into Ts cells, which inhibit the response of fresh T cells to the primary allogeneic stimulator cell but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5333aaa3270168e6afdffa4eedd6719d
https://doi.org/10.4049/jimmunol.144.1.32
https://doi.org/10.4049/jimmunol.144.1.32