Zobrazeno 1 - 10
of 28
pro vyhledávání: '"E F Rosloniec"'
Publikováno v:
The Journal of Immunology. 161:3589-3595
Immunization of susceptible strains of mice with type II collagen (CII) elicits an autoimmune arthritis known as collagen-induced arthritis (CIA). One analogue peptide of the immunodominant T cell determinant, A9 (CII245–270 (I260→A, A261→B, F2
Publikováno v:
The Journal of Immunology. 158:6013-6018
Tolerization of B10.RIII mice (H-2r) with i.v.-injected type II collagen (CII) renders the animals resistant to induction of collagen-induced arthritis (CIA). The B10.RIII mouse is of particular interest, in that the T cell determinants that induce t
Publikováno v:
The Journal of Immunology. 157:5178-5184
Collagen-induced arthritis (CIA) is an experimental autoimmune disease elicited in genetically susceptible strains of mice by immunization with heterologous type II collagen. This experimental disease is mediated by the immune response of both T cell
Publikováno v:
The Journal of Immunology. 155:4504-4511
A recombinant TCR domain, derived from a T cell hybridoma that recognizes an immunodominant type II collagen epitope, was used to vaccinate against collagen-induced arthritis in DBA/1 (H-2q) mice. The recombinant TCR domain comprises VA11.1-JA17 gene
Publikováno v:
The Journal of Immunology. 152:3088-3097
Collagen-induced arthritis (CIA) is an experimental autoimmune disease elicited in genetically susceptible strains of mice by immunization with heterologous type II collagen. This experimental disease is mediated by the immune response of both T and
Publikováno v:
The Journal of Immunology. 150:4652-4658
The immunization of genetically susceptible strains of mice with type II collagen (CII) elicits a collagen-induced arthritis that resembles rheumatoid arthritis. Our laboratory previously identified a region of CII, CII-245-270, that contains a T cel
Autor:
Y B, Guedez, K B, Whittington, J L, Clayton, L A, Joosten, F A, van de Loo, W B, van den Berg, E F, Rosloniec
Publikováno v:
Arthritis and rheumatism. 44(10)
To determine whether the lack of interferon-gamma (IFNgamma) alters resistance to collagen-induced arthritis (CIA) in a nonsusceptible mouse strain, and if so, to identify changes in the antibody, cellular type II collagen (CII)-specific immune respo
Autor:
L K, Myers, A H, Kang, A E, Postlethwaite, E F, Rosloniec, S G, Morham, B V, Shlopov, S, Goorha, L R, Ballou
Publikováno v:
Arthritis and rheumatism. 43(12)
To determine the effects of cyclooxygenase 1 (COX-1) and COX-2 gene deletion on collagen-induced arthritis (CIA).Mice that were susceptible to CIA but lacked either the COX-1 or the COX-2 gene were immunized with type II collagen (CII), and the incid
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(7)
Immunization of susceptible strains of mice with type II collagen (CII) elicits an autoimmune arthritis known as collagen-induced arthritis (CIA). One analogue peptide of the immunodominant T cell determinant, A9 (CII245-270 (I260--A, A261--B, F263--
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(7)
The immunodominant T cell determinant of type II collagen (CII) recognized by DBA/1 mice (I-Aq) is CII 260-267. The aims of this study were to determine the role of the amino acid residues within CII 245-270 in T cell signal transduction. To that end