Výsledky vyhledávání

Molecular cloning, sequence, and expression of cynomolgus monkey cholesteryl ester transfer protein. Inverse correlation between hepatic cholesteryl ester transfer protein mRNA levels and plasma high density lipoprotein levels

Autor: Keith R. Marotti, E F Rehberg, George W. Melchior, M.E. Pape

Publikováno v: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 11:1759-1771

A cDNA clone containing the coding region for cynomolgus monkey cholesteryl ester transfer protein (CETP) was isolated by the polymerase chain reaction with primers based on the human CETP cDNA sequence and cDNA synthesized from liver poly (A+) RNA.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d832d9e4f00aa741ed2195be89c441c
https://doi.org/10.1161/01.atv.11.6.1759

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A novel abetalipoproteinemia genotype. Identification of a missense mutation in the 97-kDa subunit of the microsomal triglyceride transfer protein that prevents complex formation with protein disulfide isomerase

Autor: E F, Rehberg, M E, Samson-Bouma, B, Kienzle, L, Blinderman, H, Jamil, J R, Wetterau, L P, Aggerbeck, D A, Gordon

Publikováno v: The Journal of biological chemistry. 271(47)

The microsomal triglyceride transfer protein (MTP) is a heterodimer composed of the ubiquitous multifunctional protein, protein disulfide isomerase, and a unique 97-kDa subunit. Mutations that lead to the absence of a functional 97-kDa subunit cause

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ecb6c128843a73d675e1bb27b800432
https://pubmed.ncbi.nlm.nih.gov/8939939

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Purification of human cholesteryl ester transfer protein by affinity chromatography on immobilized triazine dyes

Autor: E F Rehberg, G.W. Melchior, K.A. Greenlee, K.R. Marotti

Publikováno v: Protein expression and purification. 5(3)

Human cholesteryl ester transfer protein was purified from lipoprotein-depleted serum or plasma in a three-step procedure utilizing commercially available triazine dyes immobilized on agarose. The method used consisted of successive chromatography st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee7703cb4f96749d676046c487958d8
https://pubmed.ncbi.nlm.nih.gov/7950373

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Introduction of lysine and clot binding properties in the kringle one domain of tissue-type plasminogen activator

Autor: A H, Bakker, W, van der Greef, E F, Rehberg, K R, Marotti, J H, Verheijen

Publikováno v: The Journal of biological chemistry. 268(25)

Despite the high overall similarity in primary structure between kringle one (K1) and kringle two (K2) of tissue-type plasminogen activator (t-PA) there exists an enormous functional difference. It is thought that, in contrast to K1, K2 mediates lysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88141e751d7aed97697001b63d5a714d
https://pubmed.ncbi.nlm.nih.gov/8395505

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The role of cholesteryl ester transfer protein in primate apolipoprotein A-I metabolism. Insights from studies with transgenic mice

Autor: Keith R. Marotti, E F Rehberg, George W. Melchior, H.G. Polites, C K Castle, R.W. Murray

Publikováno v: Arteriosclerosis and thrombosis : a journal of vascular biology. 12(6)

To assess the effects of cholesteryl ester transfer protein (CETP) on the primate lipoprotein profile, a transgenic mouse expressing cynomolgus monkey CETP was developed. The C57BL/6 mouse was used, and four lines expressing the primate CETP were est

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a3d952bdad71eae169131be87bc51a
https://pubmed.ncbi.nlm.nih.gov/1591233

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