Zobrazeno 1 - 7
of 7
pro vyhledávání: '"E F, Workman"'
Publikováno v:
Journal of Biological Chemistry. 252:7118-7123
Highly purified alpha-thrombin has been chemically modified in an attempt to determine which features of the molecule are important for normal platelet-thrombin interactions. Modifying agents included diisopropylphosphorofluoridate and 1-chloro-3-tos
Publikováno v:
Progress in clinical and biological research. 28
Publikováno v:
The Journal of biological chemistry. 252(20)
Highly purified alpha-thrombin has been chemically modified in an attempt to determine which features of the molecule are important for normal platelet-thrombin interactions. Modifying agents included diisopropylphosphorofluoridate and 1-chloro-3-tos
Autor:
E F, Workman, R L, Lundblad
Publikováno v:
Thrombosis and haemostasis. 39(1)
An improved method for the preparation of bovine alpha-thrombin is described. The procedure involves that activation of partially purified prothrombin with tissue thromboplastin followed by chromatography on Sulfopropyl-Sephadex C-50. The purified en
Publikováno v:
Oral Presentations.
A radioimmunoassay for the quantitation of bovine platelet factor 4 (PF4) has been developed for use on bovine plasma. The assay utilizes classical radioimmunoassay techniques; 50λ of standard or plasma are mixed with 250λ 125I- bovine PF4 and 250
Publikováno v:
The Journal of laboratory and clinical medicine. 91(1)
Platelets from two patients with Glanzmann's thrombasthenia showed decreased iodination of surface glycoproteins GPIIb and GPIII. Despite these changes, the binding of [125I] alpha-thrombin to the thrombasthenic platelets was normal. Binding was line
Autor:
D M Clark, E F Workman
Publikováno v:
Oral Presentations.
Platelet activation occurs in a variety of thrombotic disease states and may be monitored via measurement of Platelet Factor 4 (PF4) levels in plasma. In order for PF4 levels to reflect in vivo activation, care must be taken to eliminate in vitro α