Zobrazeno 1 - 10
of 45
pro vyhledávání: '"E F, Winton"'
Autor:
E F, Winton, J, Srinivasiah, B K, Kim, C D, Hillyer, E A, Strobert, J L, Orkin, R B, Swenson, H M, McClure, L A, Myers, R, Saral
Publikováno v:
Blood. 84:65-73
Using a recently developed hepsulfam-induced pancytopenia model in rhesus macaques, we have studied the effects of recombinant human interleukin-6 (rhIL-6) and rhIL-3 on marrow regeneration. Control animals were given hepsulfam (1.5 g/m2 by a single
Publikováno v:
Blood. 83:767-775
T-gamma lymphoproliferative disease (T-gamma LPD) is a chronic disorder of mature T cells that is associated with neutropenia and autoimmune phenomena. Although the progression of the lymphoproliferation is indolent, it is often associated with a mon
Autor:
H A, Pereira, J K, Spitznagel, E F, Winton, W M, Shafer, L E, Martin, G S, Guzman, J, Pohl, R W, Scott, M N, Marra, J M, Kinkade
Publikováno v:
Blood. 76:825-834
The ontogeny of a 57-Kd cationic antimicrobial protein (CAP57) that has substantial similarities to bactericidal permeability increasing protein (BPI) has been determined immunocytochemically. CAP57 was detected in the granules of mature peripheral b
Publikováno v:
Journal of Clinical Microbiology. 34:1992-1994
A 39-year-old male with acute myelogenous leukemia and concomitant porphyria cutanea tarda was admitted to the hospital for consolidation chemotherapy of his leukemia. During his hospitalization, he developed cellulitis of the left hand and persisten
Autor:
K, Toba, K, Kishi, T, Koike, E F, Winton, H, Takahashi, K, Nagai, S, Maruyama, T, Furukawa, S, Hashimoto, M, Masuko, Y, Uesugi, T, Kuroha, N, Tsukada, A, Shibata
Publikováno v:
Experimental hematology. 24(8)
Using 7-amino-actinomycin-D/pyronin Y (7AAD/PY), we analyzed the surface phenotypes and cell cycle of 22 hematopoietic cell lines based on their cellular DNA/RNA content. Populations of G1a, G1b, S, and G2M, the DNA index (DI), and the RNA index of S
Autor:
S P, Dix, J R, Wingard, R E, Mullins, I, Jerkunica, T G, Davidson, C E, Gilmore, R C, York, L S, Lin, S M, Devine, R B, Geller, L T, Heffner, C D, Hillyer, H K, Holland, E F, Winton, R, Saral
Publikováno v:
Bone marrow transplantation. 17(2)
Busulfan pharmacokinetics, specifically area under the concentration curve (AUC), have been correlated with the occurrence of veno-occlusive disease (VOD) following BMT. To evaluate the risk of VOD, we studied 66 patients who received pharmacotherape
Publikováno v:
American journal of hematology. 50(4)
A patient with neutropenia and life-threatening infections secondary to T-gamma lymphoproliferative disease, who did not respond to treatment with recombinant human G-CSF (filgrastim), was treated with filgrastin plus cyclosporine A (CyA). The patien
Autor:
H M, Lazarus, E F, Winton, S F, Williams, D, Grinblatt, M, Campion, B W, Cooper, H, Gunn, S, Manfreda, R E, Isaacs
Publikováno v:
Bone marrow transplantation. 15(6)
Our purpose was to determine the maximum tolerated dosage of rhIL-6 after high-dose cytotoxic chemotherapy and autologous BMT in patients with advanced breast cancer. Twenty patients (median age 43.5 years) received either CY and thiotepa (n = 3) or
Publikováno v:
Experimental hematology. 22(1)
We investigated the effects of rac-1-O-octadecyl-2-O-methyl-glycero-3-phosphocholine (ET-18-OCH3) and 12-O-tetradecanoylphorbol-13-acetate (TPA) on granulocyte-macrophage colony-stimulating factor (GM-CSF) binding to human leukemic cell lines HL60, U
Publikováno v:
Experimental hematology. 21(12)
In humans and nonhuman primates, the in vivo administration of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) consistently results in marked increase of megakaryocyte ploidy and size similar to that observed with interl