Zobrazeno 1 - 10
of 13
pro vyhledávání: '"E E, Sugg"'
Autor:
M, Dezube, E E, Sugg, L S, Birkemo, D K, Croom, R W, Dougherty, G N, Ervin, M K, Grizzle, M K, James, M F, Johnson, J T, Mosher
Publikováno v:
Journal of Medicinal Chemistry. 38:3384-3390
Hybrid analogs of the cholecystokinin A (CCK-A) receptor selective tetrapeptide agonist Boc-Trp-Lys(Tac)-Asp-MePhe-NH2 (1,A-71623) and the CCK-B receptor selective antagonists PD-135118 (2) and CI-988 (3) were prepared. Incorporation of the Lys(Tac)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27fef768e02c3704c4c326c8e7ff5b1
https://doi.org/10.1021/jm00017a022
https://doi.org/10.1021/jm00017a022
Autor:
Richard A. Mumford, Ray S. Dewey, E E Sugg, Georg Albers-Schönberg, Philip Davies, Hollis R. Williams, C A Dolan, Jerrold M. Liesch
Publikováno v:
Biochemical Journal. 281:519-524
The stimulation of human blood with a Ca2+ ionophore, A23187, leads to activation of polymorphonuclear leucocytes (PMN) with release of small amounts of catalyticaly active elastase, as demonstrated by the formation of a characteristic product, the N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfce102d8f5c4a1288c3fac786777d6
https://doi.org/10.1042/bj2810519
https://doi.org/10.1042/bj2810519
Publikováno v:
Pharmaceutical biotechnology. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f38ba152579c2fc7ea9ffd0d24f03f2d
https://pubmed.ncbi.nlm.nih.gov/9760694
https://pubmed.ncbi.nlm.nih.gov/9760694
Autor:
B A, Johnson, E E, Sugg
Publikováno v:
Biochemistry. 31(35)
The solution structure of chemically synthesized iberiotoxin, a scorpion toxin that blocks Ca(2+)-activated K+ channels, has been determined using 2D 1H NMR spectroscopy. Analysis of the NOEs, coupling constants, and HN-DN exchange rates indicates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e32f2f96071f4bab212a924dac0ffa46
https://pubmed.ncbi.nlm.nih.gov/1381959
https://pubmed.ncbi.nlm.nih.gov/1381959
Publikováno v:
Peptide research. 5(3)
The biological activity of amylin is reported to vary widely depending on the source and purity of the material. Three commercial samples of rat amylin were compared for structural differences. The samples were nearly identical using most of the avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a8d667527b892f6663be23d629c9de8
https://pubmed.ncbi.nlm.nih.gov/1421804
https://pubmed.ncbi.nlm.nih.gov/1421804
Publikováno v:
The Journal of biological chemistry. 266(1)
The binding of agonists and antagonists to the beta-adrenergic receptor (beta AR) is postulated to involve an ionic interaction between the amine group of the ligand and the carboxylate side chain of Asp113 in the third hydrophobic domain of the rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95ce0268fbcea008902ed2a82eceaa5e
https://pubmed.ncbi.nlm.nih.gov/1670767
https://pubmed.ncbi.nlm.nih.gov/1670767
Publikováno v:
The Journal of biological chemistry. 265(31)
Charybdotoxin (ChTX), a potent inhibitor of the high conductance Ca2(+)-activated K+ channel (PK,Ca) is a highly basic peptide isolated from venom of the scorpion Leiurus quinquestriatus hebraeus, whose primary structure has been determined (Gimenez-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8eb1e054c9afbff1a72b57e2f29f7540
https://pubmed.ncbi.nlm.nih.gov/1699936
https://pubmed.ncbi.nlm.nih.gov/1699936
Publikováno v:
Chemischer Informationsdienst. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1489bbf77d5b722bbe287325cfee4d9
https://doi.org/10.1002/chin.198619102
https://doi.org/10.1002/chin.198619102
Autor:
E E, Sugg, P S, Portoghese
Publikováno v:
Journal of medicinal chemistry. 29(10)
Analogues of leucine-enkephalinamide containing N-terminal cis- or trans-4-(3-hydroxyphenyl)-4-methylpipecolic acid were prepared to examine the conformational requirements of the N-terminal tyrosyl residue in opioid activity. The diastereomeric amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1f1ab35871a19b5dea797cb82df258d
https://pubmed.ncbi.nlm.nih.gov/3020252
https://pubmed.ncbi.nlm.nih.gov/3020252
Autor:
Corsi M; Glaxo Research Laboratories, Verona, Italy., Palea S, Pietra C, Oliosi B, Gaviraghi G, Sugg E, Van Amsterdam FT, Trist DG
Publikováno v:
The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 1994 Aug; Vol. 270 (2), pp. 734-40.