Zobrazeno 1 - 10 of 556 pro vyhledávání: '"E E, Blaak"'
1
Akademický článek
Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans
Autor: K. Verboven, K. Wouters, K. Gaens, D. Hansen, M. Bijnen, S. Wetzels, C. D. Stehouwer, G. H. Goossens, C. G. Schalkwijk, E. E. Blaak, J. W. Jocken
Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Obesity is associated with a disturbed adipose tissue (AT) function characterized by adipocyte hypertrophy, an impaired lipolysis and pro-inflammatory phenotype, which contributes to insulin resistance (IR). We investigated whether AT phenot
Externí odkaz: https://doaj.org/article/443cd9ffd09742e6ad0690ce44450891
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2
Natriuretic peptides in the control of lipid metabolism and insulin sensitivity
Autor: K, Verboven, D, Hansen, J W E, Jocken, E E, Blaak
Publikováno v: Obesity reviews : an official journal of the International Association for the Study of Obesity. 18(11)
Natriuretic peptides have long been known for their cardiovascular function. However, a growing body of evidence emphasizes the role of natriuretic peptides in human substrate and energy metabolism, thereby connecting the heart with several insulin-s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ad1687887486d0eb1183ceafe9b6789
https://pubmed.ncbi.nlm.nih.gov/28901677
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3
Improved Insulin Sensitivity With Angiotensin Receptor Neprilysin Inhibition in Individuals With Obesity and Hypertension
Autor: J, Jordan, R, Stinkens, T, Jax, S, Engeli, E E, Blaak, M, May, B, Havekes, C, Schindler, D, Albrecht, P, Pal, T, Heise, G H, Goossens, T H, Langenickel
Publikováno v: Clinical pharmacology and therapeutics. 101(2)
Natriuretic peptide (NP) deficiency and sustained renin-angiotensin system activation are associated with impaired oxidative metabolism and predispose to type-2 diabetes. We hypothesized that sacubitril/valsartan (LCZ696), which augments NP through n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eda9d793bdbdac503f4e3c0509ca68eb
https://pubmed.ncbi.nlm.nih.gov/27542885
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5
Targeting fatty acid metabolism to improve glucose metabolism
Autor: R, Stinkens, G H, Goossens, J W E, Jocken, E E, Blaak
Publikováno v: Obesity reviews : an official journal of the International Association for the Study of Obesity. 16(9)
Disturbances in fatty acid metabolism in adipose tissue, liver, skeletal muscle, gut and pancreas play an important role in the development of insulin resistance, impaired glucose metabolism and type 2 diabetes mellitus. Alterations in diet compositi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f5c6ae47df2ae69af2a458e00cb59a56
https://pubmed.ncbi.nlm.nih.gov/26179344
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6
Akademický článek
Synergistic Interplay of Diet, Gut Microbiota, and Insulin Resistance: Unraveling the Molecular Nexus.
Autor: Gopal RK; Department of Microbiology, Centre for Infectious Diseases, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University (Deemed to be University), Chennai, Tamil Nadu, 600077, India., Ganesh PS; Department of Microbiology, Centre for Infectious Diseases, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University (Deemed to be University), Chennai, Tamil Nadu, 600077, India., Pathoor NN; Department of Microbiology, Centre for Infectious Diseases, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University (Deemed to be University), Chennai, Tamil Nadu, 600077, India.
Publikováno v: Molecular nutrition & food research [Mol Nutr Food Res] 2024 Nov 16, pp. e2400677. Date of Electronic Publication: 2024 Nov 16.
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7
Monocytes, but not T cells, respond to insulin with Akt(S473) phosphorylation independent of the donor glucometabolic state
Autor: M M, Thewissen, J, van de Gaar, A Th, den Boer, M J, Munsters, E E, Blaak, A, Duijvestijn
Publikováno v: Diabetes/metabolism research and reviews. 30(4)
Obesity is associated with insulin resistance and chronic low-grade inflammation. Insulin has been described to have anti-inflammatory effects in immune cells. Therefore, insulin resistance in immune cells can be expected to have important consequenc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f28ac6a2d7a4d26638f15f78f0699630
https://pubmed.ncbi.nlm.nih.gov/24302564
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8
Akademický článek
Short‐Term Statin Therapy Induces Hepatic Insulin Resistance Through HNF4α/PAQR9/PPM1α Axis Regulated AKT Phosphorylation.
Autor: Lin, Yijun1 (AUTHOR) linyijun@xmu.edu.cn, Wang, Shuying2 (AUTHOR), Li, Zixuan2 (AUTHOR), Zhou, Yuling1 (AUTHOR), Wang, Ruiying1 (AUTHOR), Wang, Yan1 (AUTHOR), Chen, Yan2 (AUTHOR) ychen3@sibs.ac.cn
Publikováno v: Advanced Science. 9/11/2024, Vol. 11 Issue 34, p1-13. 13p.
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9
Abstracts of papers clinical pharmacological meeting
Autor: M. M. Klauw, B. H. Ch. Stricker, J. P. Ottervanger, F. G. A. Meché, J. M. T. Griensven, H. H. P. J. Lemkes, J. M. Kroon, H. C. Schoemaker, A. F. Cohen, J. H. M. Schellens, W. Loos, B. Acker, M. Boer-Dennert, A. S. T. Planting, M. E. L. Burg, G. Stoter, R. Krediet, J. Verweij, E. E. Blaak, M. A. Baak, G. J. Kemerink, M. T. W. Pakbiers, G. A. K. Heidendal, W. H. M. Saris, S. Bouckaert, L. Vakaet, M. Dhont, J. P. Remon, S. A. J. Broek, P. A. Graeff, W. H. Gilst, D. J. Veldhuisen, H. L. Hillige, H. Wesseling, K. I. Lie, C. A. Gaillard, P. N. Es, P. W. Leeuw, L. M. A. B. Bortel, M. J. F. Kool, F. A. T. Lustermans, J. G. S. Breed, A. P. G. Hoeks, H. A. J. Struijker Boudier, R. P. Pickkers, P. Smits, H. Baadenhuysen, A. Laar, Th. Thien, M. M. Elseviers, M. E. Broe, A. J. A. M. Ven, P. P. Koopmans, W. H. M. Peters, T. B. Vree, J. W. M. Meer, E. Snoeck, A. Peer, M. Sack, M. Horton, G. Mannens, R. Woestenborghs, J. Heykants, R. Meibach, T. B. Witsen, H. A. Valkenburg, R. H. Stichele, B. Potter, P. Vyncke, M. G. Bogaert, J. Burggraaf, H. Wollersheim, J. Aalen, R. G. Schoemaker, X. Y. Du, W. A. Bax, E. Bos, P. R. Saxena, G. A. Rongen, P. N. M. Heiningen, H. R. Schwietert, J. M. Kortboyer, F. A. E. Sollie, C. Piraube, P. Desché, J. H. G. Jonkman, W. L. Blok, I. C. Gyssens, Y. A. Hekster, P. A. F. Jansen, R. C. Sival, J. F. Nieuwkerk, B. Klaverwiiden, E. A. Bruijn, O. Driessen
Publikováno v: Pharmacy World & Science. 15:1-7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef2aae6a441771cb628d57e3209c1802
https://doi.org/10.1007/bf01876624
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10
Do nutrient-gut-microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes?
Autor: M, Diamant, E E, Blaak, W M, de Vos
Publikováno v: Obesity reviews : an official journal of the International Association for the Study of Obesity. 12(4)
The current obesity and type 2 diabetes pandemics have causes beyond changes in eating and exercise habits against a susceptible genetic background. Gut bacteria seem to additionally contribute to the differences in body weight, fat distribution, ins
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9de720ecf778ceaf2239427eefd12d5
https://pubmed.ncbi.nlm.nih.gov/20804522
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