To screen or nor to screen: the prostate cancer dilemma

Autor: Nelson N Stone, E David Crawford

Publikováno v: Asian Journal of Andrology, Vol 17, Iss 1, Pp 44-45 (2015)

The European Randomized Study of Screening for Prostate (ERSPC) has updated their previous seminal report on prostate cancer mortality comparing screened men to controls. Now with 13 years follow-up, the rate ratio of prostate cancer mortality was 0.

Externí odkaz: https://doaj.org/article/ee5c8cfb2e7a4d699d141929550aa293

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Autor: Alexander Gusev, Huwenbo Shi, Gleb Kichaev, Mark Pomerantz, Fugen Li, Henry W. Long, Sue A. Ingles, Rick A. Kittles, Sara S. Strom, Benjamin A. Rybicki, Barbara Nemesure, William B. Isaacs, Wei Zheng, Curtis A. Pettaway, Edward D. Yeboah, Yao Tettey, Richard B. Biritwum, Andrew A. Adjei, Evelyn Tay, Ann Truelove, Shelley Niwa, Anand P. Chokkalingam, Esther M. John, Adam B. Murphy, Lisa B. Signorello, John Carpten, M. Cristina Leske, Suh-Yuh Wu, Anslem J. M. Hennis, Christine Neslund-Dudas, Ann W. Hsing, Lisa Chu, Phyllis J. Goodman, Eric A. Klein, John S. Witte, Graham Casey, Sam Kaggwa, Michael B. Cook, Daniel O. Stram, William J. Blot, Rosalind A. Eeles, Douglas Easton, ZSofia Kote-Jarai, Ali Amin Al Olama, Sara Benlloch, Kenneth Muir, Graham G. Giles, Melissa C. Southey, Liesel M. Fitzgerald, Henrik Gronberg, Fredrik Wiklund, Markus Aly, Brian E. Henderson, Johanna Schleutker, Tiina Wahlfors, Teuvo L. J. Tammela, Børge G. Nordestgaard, Tim J. Key, Ruth C. Travis, David E. Neal, Jenny L. Donovan, Freddie C. Hamdy, Paul Pharoah, Nora Pashayan, Kay-Tee Khaw, Janet L. Stanford, Stephen N. Thibodeau, Shannon K. McDonnell, Daniel J. Schaid, Christiane Maier, Walther Vogel, Manuel Luedeke, Kathleen Herkommer, Adam S. Kibel, Cezary Cybulski, Dominika Wokolorczyk, Wojciech Kluzniak, Lisa Cannon-Albright, Craig Teerlink, Hermann Brenner, Aida K. Dieffenbach, Volker Arndt, Jong Y. Park, Thomas A. Sellers, Hui-Yi Lin, Chavdar Slavov, Radka Kaneva, Vanio Mitev, Jyotsna Batra, Amanda Spurdle, Judith A. Clements, Manuel R. Teixeira, Hardev Pandha, Agnieszka Michael, Paula Paulo, Sofia Maia, Andrzej Kierzek, The PRACTICAL consortium, David V. Conti, Demetrius Albanes, Christine Berg, Sonja I. Berndt, Daniele Campa, E. David Crawford, W. Ryan Diver, Susan M. Gapstur, J. Michael Gaziano, Edward Giovannucci, Robert Hoover, David J. Hunter, Mattias Johansson, Peter Kraft, Loic Le Marchand, Sara Lindström, Carmen Navarro, Kim Overvad, Elio Riboli, Afshan Siddiq, Victoria L. Stevens, Dimitrios Trichopoulos, Paolo Vineis, Meredith Yeager, Gosia Trynka, Soumya Raychaudhuri, Frederick R. Schumacher, Alkes L. Price, Matthew L. Freedman, Christopher A. Haiman, Bogdan Pasaniuc

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)

Over one hundred loci have been identified to be associated with the familial risk of prostate cancer but the functional effects are poorly understood. Here the authors use single-nucleotide variant and epigentic data to show an underlying genetic ar

Externí odkaz: https://doaj.org/article/e4bbdf2c86b748b69179c08e3173c667

MP29-01 RAPID, DURABLE, AND DEEP PROSTATE-SPECIFIC ANTIGEN RESPONSE FOLLOWING ADDITION OF DAROLUTAMIDE TO ANDROGEN-DEPRIVATION THERAPY AND DOCETAXEL IN ARASENS

Autor: Fred Saad, Bertrand Tombal, Maha Hussain, Karim Fizazi, Cora N. Sternberg, E. David Crawford, Luke T. Nordquist, Ronald Tutrone, Neal D. Shore, Laurence Belkoff, Shivani Kapur, Jay Jhaveri, Jorge Ortiz, Shankar Srinivasan, Frank Verholen, Matthew R. Smith

Publikováno v: Journal of Urology. 209

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::262d0fd3d19870a6557ba85069230086
https://doi.org/10.1097/ju.0000000000003257.01

Data from Refining the Prostate Cancer Genetic Association within the JAZF1 Gene on Chromosome 7p15.2

Autor: Meredith Yeager, Stephen J. Chanock, Nilanjan Chatterjee, Gilles Thomas, David J. Hunter, Joseph F. Fraumeni, Robert N. Hoover, Margaret Tucker, Merethe Kumle, Kristian Hveem, Lars J. Vatten, Jianfeng Xu, Fredrik Wiklund, Henrik Grönberg, Sarah D. Isaacs, William B. Isaacs, Rudolf Kaaks, Ruth Travis, Elio Riboli, Afshan Siddiq, Loic Le Marchand, Laurence Kolonel, Brian E. Henderson, Christopher A. Haiman, E. David Crawford, Gerald L. Andriole, Antoine Valeri, Olivier Cussenot, Geraldine Cancel-Tassin, Fredrick R. Schumacher, Stephanie Weinstein, Jarmo Virtamo, Demetrius Albanes, W. Ryan Diver, Michael J. Thun, Heather Spencer Feigelson, Amy Hutchinson, Kai Yu, Sholom Wacholder, Sonja I. Berndt, Peter Kraft, Richard B. Hayes, Kevin B. Jacobs, Wei Tang, Yi-Ping Fu, Ludmila Prokunina-Olsson

Background: Genome-wide association studies have identified multiple genetic variants associated with susceptibility to prostate cancer (PrCa). In the two-stage Cancer Genetic Markers of Susceptibility prostate cancer scan, a single-nucleotide polymo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277245a774f2da6c3f06078e0b19c2c3
https://doi.org/10.1158/1055-9965.c.6514884

Supplementary Tables 1-8 from Common Genetic Variants in Prostate Cancer Risk Prediction—Results from the NCI Breast and Prostate Cancer Cohort Consortium (BPC3)

Autor: Peter Kraft, Stephen J. Chanock, Christopher A. Haiman, Gianluca Severi, Richard B. Hayes, Meredith Yeager, Walter C. Willett, Stephanie J. Weinstein, Jarmo Virtamo, Dimitrios Trichopoulos, Anne Tjonneland, Michael J. Thun, Daniel O. Stram, Meir Stampfer, Valeria Pala, Loïc Le Marchand, Jing Ma, Laurence N. Kolonel, Mattias Johansson, David J. Hunter, Brian Henderson, Carlos A. Gonzalez, Edward Giovannucci, Graham G. Giles, J. Michael Gaziano, W. Ryan Diver, E. David Crawford, H. Bas Bueno-de-Mesquita, Heiner Boeing, Sonja I. Berndt, Gerald Andriole, Naomi E. Allen, Demetrius Albanes, Ruth C. Travis, David Cox, Fredrick R. Schumacher, Sara Lindström

PDF file - 169K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830ba3051809c59712c61eb271bdb140
https://doi.org/10.1158/1055-9965.22438200.v1