Zobrazeno 1 - 10
of 60
pro vyhledávání: '"E D du Toit"'
Publikováno v:
Tissue antigens. 85(4)
Genomic sequencing of HLA-A*30:02:01:03, an intronic variant, and HLA-C*08:113, an exonic variant.
Autor:
E. D. du Toit, A J Madrigal, Leslie Johnston-Dow, William H. Hildebrand, John D. Domena, Wilma B. Bias, Peter Parham, Ann-Margaret Little
Publikováno v:
Tissue Antigens. 42:509-517
Although the B70 antigen exhibits allele frequencies of 8-23% in African and American black populations, it remains poorly defined. Cloning and sequencing of cDNA encoding B70 antigens from six cell lines has identified a group of three closely relat
Autor:
J A Madrigal, M P Belich, W H Hildebrand, R J Benjamin, A M Little, J Zemmour, P D Ennis, F E Ward, M L Petzl-Erler, E D du Toit
Publikováno v:
The Journal of Immunology. 149:3411-3415
Alleles encoding five HLA-A and B Ag characteristic of black populations have been isolated and their nucleotide sequences determined. In each case, the "black" allele is similar to a "related" allele found in caucasoid populations. The primary diffe
Publikováno v:
Human Immunology. 31:14-19
Four non-Caucasoid families with the unusual HLA-DR,DQ haplotypes DRw17,DQw7; DR9,DQw2; DR4,DQw2; and DR4,DQw5 were studied. All four haplotypes showed identical serological patterns to those seen with the equivalent Caucasoid antigens, but no HLA-Dw
Publikováno v:
Human Immunology. 28:406-415
The HLA-A, -B, and -C antigens of 290 and the DR antigens of 212 !Kung San individuals were characterized. The most frequent antigens were HLA-A30 gene frequency ( gf ) = 0.193, Bw58 ( gf = 0.303), Cw6 ( gf = 0.327), DR4 ( gf = 0.273), and DQw3 ( gf
Publikováno v:
Human Immunology. 28:32-38
The HLA-DRB3 gene, which encodes the supertypic HLA-DRw52 antigen, has been shown to have limited polymorphism. The alleles at this locus are also in linkage disequilibrium with the alleles at the DRB1 locus. We have studied 16 DRw11 and three DRw12
New HLA-DR2-related specificities detected in South African Blacks and individuals of mixed ancestry
Publikováno v:
Tissue Antigens. 35:211-216
This study describes a new HLA-DR2-related specificity DR2LUM (CT) present in South African Blacks and individuals of mixed ancestry (Cape Coloureds). It can be distinguished from the “classic” DR2 specificities, DRw15 and DRw16, using serologica
Publikováno v:
Annals of human genetics. 63(Pt 4)
The 1080-bp coding region of the human plasma alpha(1,3)fucosyltransferase gene (FUT6) was sequenced in a total of 161 individuals (322 chromosomes) drawn from three populations, involving 56 Africans (Xhosa), 52 European-Africans of South Africa, an
Publikováno v:
Tissue antigens. 50(4)
DR51, a protein encoded by the DRB5 gene, was shown to be present in almost all DR2-positive haplotypes. Exceptions were reported, some DR2-negative samples were shown to be DR51 positive and in a number of DR2-positive samples no DR51 antigen could
Autor:
P. C. Creemers, E. D. du Toit
Publikováno v:
Tissue antigens. 47(2)
We studied C4A and C4B polymorphisms and HLA-B and -DR associations in the San, Khoi and Xhosa. C4A and C4B alleles were determined using conventional protein allotyping methods. The C4A*3, C4B*1 haplotype had a high frequency (30-55%) in all populat