Zobrazeno 1 - 9
of 9
pro vyhledávání: '"E D Michelakis"'
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 75:889-897
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::085c5197dddf7a0160b256aa4d7ac975
https://doi.org/10.1139/y97-111
https://doi.org/10.1139/y97-111
Autor:
E. D. Michelakis, G. Sutendra, P. Dromparis, L. Webster, A. Haromy, E. Niven, C. Maguire, T.-L. Gammer, J. R. Mackey, D. Fulton, B. Abdulkarim, M. S. McMurtry, K. C. Petruk
Publikováno v:
Science translational medicine. 2(31)
Solid tumors, including the aggressive primary brain cancer glioblastoma multiforme, develop resistance to cell death, in part as a result of a switch from mitochondrial oxidative phosphorylation to cytoplasmic glycolysis. This metabolic remodeling i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2f96a20c899de530c690d4bffd2d70
https://pubmed.ncbi.nlm.nih.gov/20463368
https://pubmed.ncbi.nlm.nih.gov/20463368
Autor:
E D, Michelakis, J R, Dyck, M S, McMurtry, S, Wang, X C, Wu, R, Moudgil, K, Hashimoto, L, Puttagunta, S L, Archer
Publikováno v:
Advances in experimental medicine and biology. 502
Chronic Hypoxic Pulmonary Hypertension (CH-PHT) is characterized by pulmonary artery (PA) vasoconstriction and cell proliferation/hypertrophy. PA smooth muscle cell (PASMC) contractility and proliferation are controlled by cytosolic Ca++ levels, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6803b29743da7077843ae25da295a87c
https://pubmed.ncbi.nlm.nih.gov/11950153
https://pubmed.ncbi.nlm.nih.gov/11950153
Autor:
E D, Michelakis, E K, Weir
Publikováno v:
Clinics in chest medicine. 22(3)
Chronic hypoxic pulmonary arterial hypertension, APAH, and PPAH are characterized by vasoconstriction and vascular remodeling and are associated with decreased Kv currents in PA smooth muscle cells. Although Kv2.1 is less well studied, it seems that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3846290e38badd41396d757ecdba8fb4
https://pubmed.ncbi.nlm.nih.gov/11590838
https://pubmed.ncbi.nlm.nih.gov/11590838
Autor:
E D, Michelakis, S L, Archer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::def503f4240bff6f1ff357dcf71232ae
https://pubmed.ncbi.nlm.nih.gov/10906999
https://pubmed.ncbi.nlm.nih.gov/10906999
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(3)
Appetite suppressants, such as dexfenfluramine (dex), are associated with primary pulmonary hypertension, valvular heart disease, and systemic vascular complications, such as coronary, cerebral, or mesenteric ischemia. These drugs suppress appetite b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb86ccf06f280fc3aa79e6300e896189
https://pubmed.ncbi.nlm.nih.gov/10565835
https://pubmed.ncbi.nlm.nih.gov/10565835
Publikováno v:
Chest. 114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0322cf8393e06cc7e9da4d6cbc5cbbe9
https://pubmed.ncbi.nlm.nih.gov/9676606
https://pubmed.ncbi.nlm.nih.gov/9676606
Publikováno v:
Canadian journal of physiology and pharmacology. 75(7)
Several recent observations suggest that the vascular medium is a mosaic of functionally and morphologically unique cell types. This diversity includes differences in cell phenotype and expression of cytoskeletal and contractile proteins as well as h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9905b58e5fa2d9e2dd20bd22ee8ffe8c
https://pubmed.ncbi.nlm.nih.gov/9315358
https://pubmed.ncbi.nlm.nih.gov/9315358
Publikováno v:
Physiological research. 44(6)
One explanation of the mechanism of hypoxic pulmonary vasoconstriction (HPV) suggests that hypoxia shifts the redox status of the pulmonary artery smooth muscle cell towards a more reduced state, through changes in the redox couples and the activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42b3c5b6f025cdaddd62e393448e86c5
https://pubmed.ncbi.nlm.nih.gov/8798271
https://pubmed.ncbi.nlm.nih.gov/8798271