Zobrazeno 1 - 10
of 93
pro vyhledávání: '"E Cuvelier"'
Autor:
Jacob Rozmus, Sima T. Bhatt, Nataliya Prokopenko Buxbaum, Geoffrey D. E. Cuvelier, Amanda M. Li, Carrie L. Kitko, Kirk R. Schultz
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Hematopoietic cell transplant is a curative therapy for many pediatric patients with high risk acute lymphoblastic leukemia. Its therapeutic mechanism is primarily based on the generation of an alloreactive graft-versus-leukemia effect that can elimi
Externí odkaz:
https://doaj.org/article/4881039bbf99479fb733dbb0a3d8be98
A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol
Autor:
Anshika Jain, Ryan Huang, Jasmine Lee, Natasha Jawa, Yong Jin Lim, Mike Guron, Sharon Abish, Paul C. Boutros, Michael Brudno, Bruce Carleton, Geoffrey D. E. Cuvelier, Lakshman Gunaratnam, Cheryl Ho, Khosrow Adeli, Sara Kuruvilla, Giles Lajoie, Geoffrey Liu, Paul C. Nathan, Shahrad Rod Rassekh, Michael Rieder, Sushrut S. Waikar, Stephen A. Welch, Matthew A. Weir, Eric Winquist, David S. Wishart, Alexandra P. Zorzi, Tom Blydt-Hansen, Michael Zappitelli, Bradley Urquhart
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 8 (2021)
Background: Cisplatin, a chemotherapy used to treat solid tumors, causes acute kidney injury (AKI), a known risk factor for chronic kidney disease and mortality. AKI diagnosis relies on biomarkers which are only measurable after kidney damage has occ
Externí odkaz:
https://doaj.org/article/15b7986c609a42cb8982f5a706c42a37
Autor:
Geoff D. E. Cuvelier, Amanda Li, Sibyl Drissler, Amina Kariminia, Sayeh Abdossamadi, Jacob Rozmus, Jean-Pierre Chanoine, Bernard Ng, Sara Mostafavi, Ryan R. Brinkman, Kirk R. Schultz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
It is established that pediatric hematopoietic stem cell transplant (HSCT) recipients have a lower rate of chronic graft-versus-host disease (cGvHD) compared to adults. Our group has previously published immune profiles changes associated with cGvHD
Externí odkaz:
https://doaj.org/article/4830d325e8de432cb647a864796d1c36
Autor:
Alice Y. Chan, Jennifer W. Leiding, Xuerong Liu, Brent R. Logan, Lauri M. Burroughs, Eric J. Allenspach, Suzanne Skoda-Smith, Gulbu Uzel, Luigi D. Notarangelo, Mary Slatter, Andrew R. Gennery, Angela R. Smith, Sung-Yun Pai, Michael B. Jordan, Rebecca A. Marsh, Morton J. Cowan, Christopher C. Dvorak, John A. Craddock, Susan E. Prockop, Shanmuganathan Chandrakasan, Neena Kapoor, Rebecca H. Buckley, Suhag Parikh, Deepak Chellapandian, Benjamin R. Oshrine, Jeffrey J. Bednarski, Megan A. Cooper, Shalini Shenoy, Blachy J. Davila Saldana, Lisa R. Forbes, Caridad Martinez, Elie Haddad, David C. Shyr, Karin Chen, Kathleen E. Sullivan, Jennifer Heimall, Nicola Wright, Monica Bhatia, Geoffrey D. E. Cuvelier, Frederick D. Goldman, Isabelle Meyts, Holly K. Miller, Markus G. Seidel, Mark T. Vander Lugt, Rosa Bacchetta, Katja G. Weinacht, Jeffrey R. Andolina, Emi Caywood, Hey Chong, Maria Teresa de la Morena, Victor M. Aquino, Evan Shereck, Jolan E. Walter, Morna J. Dorsey, Christine M. Seroogy, Linda M. Griffith, Donald B. Kohn, Jennifer M. Puck, Michael A. Pulsipher, Troy R. Torgerson
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Primary Immune Regulatory Disorders (PIRD) are an expanding group of diseases caused by gene defects in several different immune pathways, such as regulatory T cell function. Patients with PIRD develop clinical manifestations associated with diminish
Externí odkaz:
https://doaj.org/article/a25da82b983d4175a8a4ab79f5cbf956
Publikováno v:
L'Encéphale. 48:700-711
Autor:
Nicolas Waespe, Santhosh Dhanraj, Manju Wahala, Elena Tsangaris, Tom Enbar, Bozana Zlateska, Hongbing Li, Robert J. Klaassen, Conrad V. Fernandez, Geoff D. E. Cuvelier, John K. Wu, Yves D. Pastore, Mariana Silva, Jeffrey H. Lipton, Joseé Brossard, Bruno Michon, Sharon Abish, MacGregor Steele, Roona Sinha, Mark J. Belletrutti, Vicky R. Breakey, Lawrence Jardine, Lisa Goodyear, Liat Kofler, Michaela Cada, Lillian Sung, Mary Shago, Stephen W. Scherer, Yigal Dror
Publikováno v:
npj Genomic Medicine, Vol 2, Iss 1, Pp 1-8 (2017)
Blood disorders: impact of genomic structural variation Copy number variation in patients with inherited bone marrow failure syndromes (IBMFSs) is associated with more severe clinical symptoms. In addition to persistently low levels of red blood cell
Externí odkaz:
https://doaj.org/article/fab055366f7246f79c31483ee2eaa142
Akademický článek
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Autor:
Kelly R. McMahon, Shahrad Rod Rassekh, Kirk R. Schultz, Maury Pinsk, Tom Blydt-Hansen, Cherry Mammen, Ross T. Tsuyuki, Prasad Devarajan, Geoff D. E. Cuvelier, Lesley G. Mitchell, Sylvain Baruchel, Ana Palijan, Bruce C. Carleton, Colin J. D. Ross, Michael Zappitelli
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 4 (2017)
Background: Childhood cancer survivors experience adverse drug events leading to lifelong health issues. The Applying Biomarkers to Minimize Long-Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) team was established to validate and apply
Externí odkaz:
https://doaj.org/article/32e16016fb1a4c4bb457e5058139481e
Autor:
Kelly R, McMahon, Asaf, Lebel, Shahrad Rod, Rassekh, Kirk R, Schultz, Tom D, Blydt-Hansen, Geoffrey D E, Cuvelier, Cherry, Mammen, Maury, Pinsk, Bruce C, Carleton, Ross T, Tsuyuki, Colin J D, Ross, Louis, Huynh, Mariya, Yordanova, Frédérik, Crépeau-Hubert, Stella, Wang, Ana, Palijan, Jasmine, Lee, Debbie, Boyko, Michael, Zappitelli
Publikováno v:
Pediatric nephrology (Berlin, Germany).
Few studies describe acute kidney injury (AKI) burden during paediatric cisplatin therapy and post-cisplatin kidney outcomes. We determined risk factors for and rate of (1) AKI during cisplatin therapy, (2) chronic kidney disease (CKD) and hypertensi
Autor:
Geoffrey D. E. Cuvelier, Brent R. Logan, Susan E. Prockop, Rebecca H. Buckley, Caroline Y. Kuo, Linda M. Griffith, Xuerong Liu, Alison Yip, Michael S. Hershfield, Paul G. Ayoub, Theodore B. Moore, Morna J. Dorsey, Richard J. O’Reilly, Neena Kapoor, Sung-Yun Pai, Malika Kapadia, Christen L. Ebens, Lisa R. Forbes Satter, Lauri M. Burroughs, Aleksandra Petrovic, Deepak Chellapandian, Jennifer Heimall, David C. Shyr, Ahmad Rayes, Jeffrey J. Bednarski, Sharat Chandra, Shanmuganathan Chandrakasan, Alfred P. Gillio, Lisa Madden, Troy C. Quigg, Emi H. Caywood, Blachy J. Dávila Saldaña, Kenneth DeSantes, Hesham Eissa, Frederick D. Goldman, Jacob Rozmus, Ami J. Shah, Mark T. Vander Lugt, Monica S. Thakar, Roberta E. Parrott, Caridad Martinez, Jennifer W. Leiding, Troy R. Torgerson, Michael A. Pulsipher, Luigi D. Notarangelo, Morton J. Cowan, Christopher C. Dvorak, Elie Haddad, Jennifer M. Puck, Donald B. Kohn
Publikováno v:
Blood. 140(7)
Adenosine deaminase (ADA) deficiency causes ∼13% of cases of severe combined immune deficiency (SCID). Treatments include enzyme replacement therapy (ERT), hematopoietic cell transplant (HCT), and gene therapy (GT). We evaluated 131 patients with A