Zobrazeno 1 - 10
of 266
pro vyhledávání: '"E Cundliffe"'
Autor:
G Stratigopoulos, E Cundliffe
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 28:219-224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62c3a24382db81cae5a889cb14a57297
https://doi.org/10.1038/sj.jim.7000234
https://doi.org/10.1038/sj.jim.7000234
Publikováno v:
Scopus-Elsevier
Genes conferring resistance to macrolide, lincosamide, and streptogramin B (MLS) antibiotics via ribosomal modification are widespread in bacteria, including clinical isolates and MLS-producing actinomycetes. Such erm-type genes encode enzymes that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0730b71e517782440c6c671d0816cf5d
https://doi.org/10.1128/aac.40.3.581
https://doi.org/10.1128/aac.40.3.581
Autor:
E Cundliffe
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:348-352
Inducible resistance to macrolide antibiotics in Streptomyces lividans involves MGT, a macrolide glycosyl transferase that utilizes UDP-glucose as cofactor. Substrates for MGT include macrolides with 12-, 14-, 15-, or 16-atom cyclic polyketide lacton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ae29385cc48c8e4c14a7783d2391d9
https://doi.org/10.1128/aac.36.2.348
https://doi.org/10.1128/aac.36.2.348
Autor:
E. Cundliffe, J. P. G. Ballesta
Publikováno v:
Journal of Bacteriology. 173:7213-7218
Ribosomal resistance to pactamycin in clones of Streptomyces lividans containing DNA (pct) from Streptomyces pactum, the pactamycin producer, involves methylation of 16S RNA. The modified residue A-941 in S. lividans 16S rRNA (A-964 in the homologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8339edc5ec957242d6740544e1c3d5db
https://doi.org/10.1128/jb.173.22.7213-7218.1991
https://doi.org/10.1128/jb.173.22.7213-7218.1991
Publikováno v:
Journal of industrial microbiologybiotechnology. 28(3)
In the genome of Streptomyces fradiae, the three tylM genes are codirectional with the upstream gene, tylGV. Although the introduction of transcriptional blocks into the tylM genes revealed that they are normally cotranscribed, expression of tylMI st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fca75ef00900aab8cbb29340b0ad23c
https://pubmed.ncbi.nlm.nih.gov/12074090
https://pubmed.ncbi.nlm.nih.gov/12074090
Publikováno v:
Antonie van Leeuwenhoek. 79(3-4)
The tylosin-biosynthetic (tyl) gene cluster occupies about 1% of the genome of Streptomycesfradiae and includes at least 43 open reading frames. In addition to structural genes required for tylosin production, the tyl cluster contains three resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::455ab8a5e7c6cff907257cf8429d584a
https://pubmed.ncbi.nlm.nih.gov/11816964
https://pubmed.ncbi.nlm.nih.gov/11816964
Autor:
G, Stratigopoulos, E, Cundliffe
Publikováno v:
Journal of industrial microbiologybiotechnology. 28(4)
Remarkably few changes of significance seem to have occurred within the tylosin-biosynthetic gene cluster of Streptomyces fradiae during an extensive portion of the empirical strain improvement programme carried out at Lilly Research Laboratories ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe6fe49bcdfd621d35f51e1803e91263
https://pubmed.ncbi.nlm.nih.gov/11986923
https://pubmed.ncbi.nlm.nih.gov/11986923
Publikováno v:
Journal of molecular biology. 287(1)
Micrococcin-resistant mutants of Bacillus megaterium that carry mutations affecting ribosomal protein L11 have been characterised. The mutants fall into two groups. "L11-minus" strains containing an L11 gene with deletions, insertions or nonsense mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c515c9e4478133e93f39a8851bb85cb7
https://pubmed.ncbi.nlm.nih.gov/10074405
https://pubmed.ncbi.nlm.nih.gov/10074405
Autor:
E, Cundliffe
Publikováno v:
Ciba Foundation symposium. 171
Various ways in which antibiotic-producing organisms are able to resist the actions of their products are discussed. Examples are given of antibiotic inactivation and also the modification of antibiotic target sites (most notably, ribosomes) to which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25364ad88cc40f4a26a521c887682a5e
https://pubmed.ncbi.nlm.nih.gov/1302178
https://pubmed.ncbi.nlm.nih.gov/1302178
Autor:
E, Cundliffe
Publikováno v:
Journal of industrial microbiology. 7(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5611da652955861f90ca7f74a2e37c18
https://pubmed.ncbi.nlm.nih.gov/1367125
https://pubmed.ncbi.nlm.nih.gov/1367125