Zobrazeno 1 - 10
of 3 422
pro vyhledávání: '"E Coleman"'
Autor:
Rylee Matheson, Courtney L. Sexton, Catherine F. Wise, Janice O’Brien, Amber J. Keyser, Mandy Kauffman, Matthew D. Dunbar, DAP Consortium, Joshua M. Akey, Brooke Benton, Elhanan Borenstein, Marta G. Castelhano, Amanda E. Coleman, Kate E. Creevy, Kyle Crowder, Virginia R. Fajt, Annette L. Fitzpatrick, Unity Jeffery, Erica C Jonlin, Matt Kaeberlein, Elinor K. Karlsson, Kathleen F. Kerr, Jonathan M. Levine, Jing Ma, Robyn L McClelland, Daniel E.L. Promislow, Audrey Ruple, Stephen M. Schwartz, Sandi Shrager, Noah Snyder-Mackler, M. Katherine Tolbert, Silvan R. Urfer, Benjamin S. Wilfond
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionCompanion animals offer a unique opportunity to investigate risk factors and exposures in our shared environment. Passive sampling techniques have proven effective in capturing environmental exposures in dogs and humans.MethodsIn a pilot
Externí odkaz:
https://doaj.org/article/d026a8041d8a468c8110320df8400a04
Autor:
C. E. Arundel, L. K. Clark, A. Parker, D. Beard, E. Coleman, C. Cooper, D. Devane, S. Eldridge, S. Galvin, K. Gillies, C. E. Hewitt, C. Sutton, D. J. Torgerson, S. Treweek, the PROMETHEUS GROUP
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Evidence to support decisions on trial processes is minimal. One way to generate this evidence is to use a Study Within A Trial (SWAT) to test trial processes or explore methodological uncertainties. SWAT evidence relies on replic
Externí odkaz:
https://doaj.org/article/1ca788c46e6c4bb984bc31201e963f03
Autor:
Jennifer L. Zack, Shawnika J. Hull, Megan E. Coleman, Peggy Peng Ye, Pamela S. Lotke, Adam Visconti, Jason Beverley, Ashley Brant, Patricia Moriarty, Rachel K. Scott
Publikováno v:
Therapeutic Advances in Infectious Disease, Vol 11 (2024)
Background: Pre-exposure prophylaxis (PrEP) utilization among cisgender women (subsequently ‘women’) is low across age groups, relative to their risk of HIV acquisition. We hypothesize that age-related differences in psychosocial factors also inf
Externí odkaz:
https://doaj.org/article/f1391afdbdc54af29f21329f6eacd323
Autor:
Manuela Corti, Barry J. Byrne, Dominic J. Gessler, Grace Thompson, Samantha Norman, Jenna Lammers, Kirsten E. Coleman, Cristina Liberati, Melissa E. Elder, Maria L. Escolar, Ibrahim S. Tuna, Clementina Mesaros, Gary I. Kleiner, Deborah S. Barbouth, Heather L. Gray-Edwards, Nathalie Clement, Brian D. Cleaver, Guangping Gao
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 303-314 (2023)
Gene replacement therapy is a rational therapeutic strategy and clinical intervention for neurodegenerative disorders like Canavan disease, a leukodystrophy caused by biallelic mutations in the aspartoacylase (ASPA) gene. We aimed to investigate whet
Externí odkaz:
https://doaj.org/article/9c3eeeaf5a4542ada6da05e007811039
Publikováno v:
Metals, Vol 14, Iss 6, p 692 (2024)
A competing-rates model is presented to account for operational changes in the metastable β-Zr phase of the Zr-2.5Nb alloy used to make CANDU reactor pressure tubes and is used to predict temperature gradients at the outlet rolled joints using the d
Externí odkaz:
https://doaj.org/article/24a2da3c4ba34d4da1d2b69843acd588
Autor:
Boyuan Yan, Suresh Viswanathan, Scott E. Brodie, Wen-Tao Deng, Kirsten E. Coleman, William W. Hauswirth, Sheila Nirenberg
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 406-417 (2023)
Optogenetic gene therapies offer a promising strategy for restoring vision to patients with retinal degenerative diseases, such as retinitis pigmentosa (RP). Several clinical trials have begun in this area using different vectors and optogenetic prot
Externí odkaz:
https://doaj.org/article/7c6b4f3a22b54425a4e36725bb472ee2
Autor:
Kiersten K. Forsyth, Brianah M. McCoy, Sarah M. Schmid, Daniel E. L. Promislow, Noah Snyder-Mackler, the DAP Consortium, Joshua M. Akey, Brooke Benton, Elhanan Borenstein, Marta G. Castelhano, Amanda E. Coleman, Kate E. Creevy, Kyle Crowder, Matthew D. Dunbar, Virginia R. Fajt, Annette L. Fitzpatrick, Unity Jeffery, Erica C Jonlin, Matt Kaeberlein, Elinor K. Karlsson, Kathleen F. Kerr, Jonathan M. Levine, Jing Ma, Robyn L McClelland, Audrey Ruple, Stephen M. Schwartz, Sandi Shrager, M. Katherine Tolbert, Silvan R. Urfer, Benjamin S. Wilfond
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionLarge scale data on the prevalence of diverse medical conditions among dog breeds in the United States are sparse. This cross-sectional study sought to estimate the lifetime prevalence of medical conditions among US dogs and to determine
Externí odkaz:
https://doaj.org/article/364df0fc30b3463485ed60d13efb7929
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
A high-quality chromosome-scale reference genome for the invasive weed Bromus tectorum is assembled and its utility demonstrated through a genome wide association study identifying QTLs that affect reproductive phenology and plant height.
Externí odkaz:
https://doaj.org/article/797ebdaa889c4473889bba4971888a8d
Autor:
Albert M. E. Coleman
Publikováno v:
Bangladesh Journal of Bioethics, Vol 14, Iss 2 (2023)
Knowledge, attitude and practice (KAP) on healthcare professional's (HCP) ethical practice have been studied extensively in countries with developed economies. On the other hand studies in lower and middle-income countries (LMIC), especially in Sub-S
Externí odkaz:
https://doaj.org/article/221ea6785f3047178968d2fc0f072139
Autor:
Kate E. Coleman, Yandong Yin, Sarah Kit Leng Lui, Sarah Keegan, David Fenyo, Duncan J. Smith, Eli Rothenberg, Tony T. Huang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Here the authors provide mechanistic insights into how auto-cleavage of the USP1 deubiquitinase regulates DNA replication and genome stability. Implications for the targeting of USP1 activity via protein-DNA trapping in cancer therapy are discussed.
Externí odkaz:
https://doaj.org/article/000e432cb2774ebca453ed5d0d729f67