Zobrazeno 1 - 10
of 1 027
pro vyhledávání: '"E Choy"'
Autor:
Jae Sung Lim, Eun Jae Jeon, Hye Sun Go, Hyung-Jin Kim, Kye Young Kim, Thi Quynh Trang Nguyen, Da Young Lee, Kyu Suk Kim, Federico Pietrocola, Seol Hee Hong, Shee Eun Lee, Kyoung-Shim Kim, Tae-Shin Park, Dong-Hee Choi, Yu-Jin Jeong, Jong-Hwan Park, Hyeon Sik Kim, Jung-Joon Min, Yong Sook Kim, Joon Tae Park, Jae-Ho Cho, Gil-Woo Lee, Ji Hyeon Lee, Hyon E. Choy, Sang Chul Park, Chul-Ho Lee, Joon Haeng Rhee, Manuel Serrano, Kyung A Cho
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Addressing age-related immunological defects through therapeutic interventions is essential for healthy aging, as the immune system plays a crucial role in controlling infections, malignancies, and in supporting tissue homeostasis and repair
Externí odkaz:
https://doaj.org/article/cf7c542e5ba24240af9068e8d02ba7f1
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100745- (2023)
We report here a novel anti-cancer therapy based on an avian-host-specific serotype Salmonella enterica serovar Gallinarum (S. Gallinarum) deficient in ppGpp synthesis. To monitor the tumor targeting, a bioluminescent ΔppGpp S. Gallinarum was constr
Externí odkaz:
https://doaj.org/article/93cc5fcc7ad9476283da16593bfa5830
Publikováno v:
Mobile DNA, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract Antimicrobial resistant pathogens are a global health threat driven by the indiscriminate use of antimicrobials. Antimicrobial resistance can be acquired by resistance genes encoded by mobile genetic elements. In this study, we identified a
Externí odkaz:
https://doaj.org/article/f225efa27f5e4ab1b4a8f05ace2e17bd
Autor:
Yeong-Bin Baek, Hyung-Jun Kwon, Muhammad Sharif, Jeongah Lim, In-Chul Lee, Young Bae Ryu, Jae-In Lee, Ji-Sun Kim, Young-Seung Lee, Dong-Hoon Kim, Sang-Ik Park, Don-Kyu Kim, Jeong-Sun Kim, Hyon E. Choy, Sunwoo Lee, Hueng-Sik Choi, Timothy F. Osborne, Tae-Il Jeon, Kyoung-Oh Cho
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract The biosynthesis of host lipids and/or lipid droplets (LDs) has been studied extensively as a putative therapeutic target in diverse viral infections. However, directly targeting the LD lipolytic catabolism in virus-infected cells has not be
Externí odkaz:
https://doaj.org/article/48b91d4301c04a9aa8ecff65754a81e2
Autor:
Misun Yun, Sung-Hwan You, Vu Hong Nguyen, Jaya Prakash, Sarah Glasl, Vipul Gujrati, Hyon E. Choy, Andre C. Stiel, Jung-Joon Min, Vasilis Ntziachristos
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Bacteria-mediated cancer-targeted therapy is a novel experimental strategy for the treatment of cancers. Bacteria can be engineered to overcome a major challenge of existing therapeutics by differentiating between malignant and healthy tissu
Externí odkaz:
https://doaj.org/article/5d8c0beaaac745f7a00f1c66b6ccbcd8
Autor:
Seung Woo Ahn, Se Hee Lee, Uh Jin Kim, Hee-Chang Jang, Hak-Jong Choi, Hyon E. Choy, Seung Ji Kang, Seong Woon Roh
Publikováno v:
Gut Pathogens, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background Clostridioides difficile infection (CDI) is an infectious nosocomial disease caused by Clostridioides difficile, an opportunistic pathogen that occurs in the intestine after extensive antibiotic regimens. Results Nine C. difficile
Externí odkaz:
https://doaj.org/article/af97237a12da4321a316a835ca3f61f1
Autor:
Jin Kyung Kim, Yi Sak Kim, Hye-Mi Lee, Hyo Sun Jin, Chiranjivi Neupane, Sup Kim, Sang-Hee Lee, Jung-Joon Min, Miwa Sasai, Jae-Ho Jeong, Seong-Kyu Choe, Jin-Man Kim, Masahiro Yamamoto, Hyon E. Choy, Jin Bong Park, Eun-Kyeong Jo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in neuronal systems, but the potential role for such neurotransmitters on the immune system are emerging. Here the authors show GABA signaling is linked to autophagy, enhancing the
Externí odkaz:
https://doaj.org/article/c8d77fa23b514ad384c99df5991f346a
Autor:
Daejin Lim, Kwang Soo Kim, Jae-Ho Jeong, Oriana Marques, Hyun-Ju kim, Miryoung Song, Tae-Hoon Lee, Jae Il Kim, Hueng-Sik Choi, Jung-Joon Min, Dirk Bumann, Martina U. Muckenthaler, Hyon E. Choy
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The effects of iron on vacuole-resident Salmonella in macrophages are unclear. Here the authors show that the bacteria are not subject to nutritional inhibition by iron deprivation, but that iron depletion in the vacuole, via the hepcidin-ferroportin
Externí odkaz:
https://doaj.org/article/68a93fbb5483477d97468789d3299179
Autor:
So-Hyun Lee, Tai-Seung Nam, Kun-Hee Kim, Jin Hee Kim, Woong Yoon, Suk-Hee Heo, Min Jung Kim, Boo Ahn Shin, Ming-Der Perng, Hyon E. Choy, Jihoon Jo, Myeong-Kyu Kim, Seok-Yong Choi
Publikováno v:
BMC Neurology, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Alexander disease (AxD) is an astrogliopathy that predominantly affects the white matter of the central nervous system (CNS), and is caused by a mutation in the gene encoding the glial fibrillary acidic protein (GFAP), an intermed
Externí odkaz:
https://doaj.org/article/b59d8d53adf148b0bae0da01012b67a5
Supplementary Figure 1 from Genetically Engineered Salmonella typhimurium as an Imageable Therapeutic Probe for Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0492e6d89550fd9b62fc2dc26c243273
https://doi.org/10.1158/0008-5472.22382906
https://doi.org/10.1158/0008-5472.22382906