Zobrazeno 1 - 10
of 37
pro vyhledávání: '"E C Lattime"'
Publikováno v:
The Journal of urology. 166(4)
Vaccinia virus is a DNA poxvirus previously used as a vaccine to eradicate smallpox. The virus has a high efficiency of infection, replicates in the cytoplasm without chromosomal integration and can transport a large amount of recombinant DNA without
Autor:
S G, Lutzker, E C, Lattime
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(1)
Publikováno v:
Advances in experimental medicine and biology. 465
Publikováno v:
Cancer research. 59(4)
Interleukin (IL)-10 is a potent immunosuppressive cytokine that has been found to be present at the tumor site in a wide variety of human cancers, including transitional cell carcinoma of the bladder. Using a murine bladder tumor (MB49), which we sho
Publikováno v:
Cancer treatment and research. 94
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(8)
Interleukin 10 (IL-10) has the physiological role of down-regulating cell-mediated immunity. We have recently reported that mRNA for IL-10 was present in most metastatic melanoma tissues. The purpose of this investigation was to determine whether mel
Publikováno v:
The Journal of urology. 155(3)
The growth of human bladder transitional cell carcinoma (TCC) in scid/scid mice was examined.Cystocopically obtained TCC biopsies were implanted in scid/scid mice, and successful xenografts were compared with original tumors for growth and genetic ch
Publikováno v:
Seminars in oncology. 23(1)
Studies by a number of investigators have focused on inducing tumor-specific immunity as a therapeutic approach to cancer. Successful immunotherapeutic strategies have involved localized treatment with immune-active adjuvants, systemic administration
Autor:
E C, Lattime, S L, Gerson
Publikováno v:
Seminars in oncology. 23(1)
Publikováno v:
Cancer research. 54(13)
Intratumoral gene transfer may be a significant tool in active immunotherapy. The ability to insert functional genes into a tumor in vitro and in vivo using recombinant vaccinia vectors was examined in the murine bladder tumor model. Vaccinia recombi