Výsledky vyhledávání - "E C Forsberg"

Cyp1b1‐mediated suppression of lymphoid progenitors in bone marrow by polycyclic aromatic hydrocarbons coordinately impacts spleen and thymus: a selective role for the Ah Receptor

Autor: Alhaji U. N’jai, Michele Campaigne Larsen, Charles J. Czuprynski, David L. Alexander, Catherine M. Rondelli, E C. Forsberg, Colin R. Jefcoate

Publikováno v: Pharmacology Research & Perspectives

Bone marrow (BM) hematopoietic stem cells differentiate to common lymphoid progenitors (CLP) that emigrate to the thymus to form T cells or differentiate into immature B cells that then migrate to the spleen for maturation. Rapid in vivo suppression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4673fe7adeae1bb516f6b132f03a785
https://doi.org/10.1002/prp2.245

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Direct interaction of NF-E2 with hypersensitive site 2 of the β-globin locus control region in living cells

Autor: Karen M. Downs, Emery H. Bresnick, E C Forsberg

Publikováno v: Blood. 96:334-339

The human β-globin locus control region (LCR) confers high-level, tissue-specific expression to the β-globin genes. Tandem Maf recognition elements (MAREs) within the hypersensitive site 2 (HS2) subregion of the LCR are important for the strong enh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624f80e19637518ad4baf2ee662397d5
https://doi.org/10.1182/blood.v96.1.334

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Physical and Functional Interactions between the Transactivation Domain of the Hematopoietic Transcription Factor NF-E2 and WW Domains

Autor: Ney Pa, Emery H. Bresnick, E C Forsberg, Eric A. Mosser, Brian K. Kay, Jeremy Kasanov

Publikováno v: Biochemistry. 37:13686-13695

Tandem binding sites for the hematopoietic transcription factor NF-E2 in the beta-globin locus control region activate high-level beta-globin gene expression in transgenic mice. NF-E2 is a heterodimer consisting of a hematopoietic subunit p45 and a u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5da3ba41dd3ad7a662715991547ecff
https://doi.org/10.1021/bi981310l

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Human Histone Acetyltransferase GCN5 Exists in a Stable Macromolecular Complex Lacking the Adapter ADA2

Autor: Emery H. Bresnick, Y Nakatani, E C Forsberg, Lloyd T. Lam, X J Yang

Publikováno v: Biochemistry. 36:15918-15924

Acetylation of core histones is an important regulatory step in transcriptional activation from chromatin templates. The yeast transcriptional coactivator protein GCN5 was recently shown to be a nuclear histone acetyltransferase (HAT). Genetic and bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926ff3dbe98e9d5a35fb908ec01aef99
https://doi.org/10.1021/bi971664x

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Direct interaction of NF-E2 with hypersensitive site 2 of the beta-globin locus control region in living cells

Autor: E C, Forsberg, K M, Downs, E H, Bresnick

Publikováno v: Blood. 96(1)

The human beta-globin locus control region (LCR) confers high-level, tissue-specific expression to the beta-globin genes. Tandem Maf recognition elements (MAREs) within the hypersensitive site 2 (HS2) subregion of the LCR are important for the strong

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3796240bed7335a937a176026bb563f
https://pubmed.ncbi.nlm.nih.gov/10891470

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