Zobrazeno 1 - 10
of 45
pro vyhledávání: '"E C, Theil"'
Autor:
E. C. Theil, R. Leipuviene
Publikováno v:
Cellular and Molecular Life Sciences. 64:2945-2955
The life of aerobes is dependent on iron and oxygen for efficient bioenergetics. Due to potential risks associated with iron/oxygen chemistry, iron acquisition, concentration, storage, utilization, and efflux are tightly regulated in the cell. A cent
Autor:
E C Theil
Publikováno v:
Biochemical Journal. 304:1-11
Publikováno v:
Biology of Metals. 3:171-175
The release of iron from ferritin is important in the formation of iron proteins and for the management of diseases in both animals and plants associated with abnormal accumulations of ferritin iron. Much more iron can be released experimentally by r
Autor:
E. C. Theil, Korry J. Hintze
Publikováno v:
Cellular and molecular life sciences : CMLS. 63(5)
Controlling iron/oxygen chemistry in biology depends on multiple genes, regulatory messenger RNA (mRNA) structures, signaling pathways and protein catalysts. Ferritin, a protein nanocage around an iron/oxy mineral, centralizes the control. Complement
Publikováno v:
The Journal of biological chemistry. 273(37)
A family of noncoding mRNA sequences, iron-responsive elements (IREs), coordinately regulate several mRNAs through binding a family of mRNA-specific proteins, iron regulatory proteins (IRPs). IREs are hairpins with a constant terminal loop and base-p
Publikováno v:
The Journal of biological chemistry. 273(30)
How and where iron exits from ferritin for cellular use is unknown. Twenty-four protein subunits create a cavity in ferritin where iron is concentrated10(11)-fold as a mineral. Proline substitution for conserved leucine 134 (L134P) allowed normal ass
Publikováno v:
European journal of clinical nutrition. 51
To stimulate novel sustainable solutions to the problem of the nutritional iron deficiency, we asked: How does Nature insure proper iron nutrition of embryos and neonatal animals? Estimates of iron deficiency world-wide are 30% of the population, wit
Autor:
E C, Theil
Publikováno v:
Metal ions in biological systems. 35
Autor:
H, Sierzputowska-Gracz, E C, Theil
Publikováno v:
Nucleic acids symposium series. (33)
Noncoding sequences regulate mRNA and DNA function. IREs are a highly conserved family of noncoding mRNA sequences which coordinate ferritin mRNA translation and transferrin receptor mRNA stability by interactions with specific negative regulator pro
Publikováno v:
Advances in experimental medicine and biology. 356
The synthesis of least three proteins involved in iron metabolism is coordinately regulated in animals through noncoding sequences in mRNA, the IREs; the transcription of the genes encoding the proteins are also regulated. Cellular iron is the best k