Zobrazeno 1 - 10
of 12
pro vyhledávání: '"E C, Strain"'
Publikováno v:
Psychopharmacology. 123:15-25
The present study was conducted to determine whether methadone maintenance alters the pharmacodynamic effects of single doses of cocaine. Twenty-two current users of IV cocaine who were not seeking treatment for their illicit cocaine use participated
Autor:
E. C. Strain
Publikováno v:
JAMA: The Journal of the American Medical Association. 272:1043-1048
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(1)
Preclinical studies have demonstrated that kappa-opioid agonists can attenuate the neurochemical and behavioral effects of cocaine that are related to its reinforcing efficacy, suggesting that kappa-agonists may serve as pharmacotherapies for cocaine
Autor:
T, Eissenberg, G E, Bigelow, E C, Strain, S L, Walsh, R K, Brooner, M L, Stitzer, R E, Johnson
Publikováno v:
JAMA. 277(24)
To compare the clinical efficacy of different doses of levomethadyl acetate hydrochloride (known as LAAM) in the treatment of opioid dependence.A randomized controlled, double-blind, parallel group, 17-week study.Outpatient facilities at Johns Hopkin
Publikováno v:
NIDA research monograph. 162
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(2)
Buprenorphine is an opioid partial agonist being developed for possible use in the treatment of opioid dependence. In a previous study up to 8 mg of buprenorphine administered 20 hr after a daily dose of methadone in methadone-maintained volunteers p
Publikováno v:
JAMA. 272(13)
The extent to which daily caffeine use is associated with a substance dependence syndrome similar to that associated with other psychoactive drugs is unknown. The purpose of this study was to assess volunteers who reported problems with their use of
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 267(2)
Pentazocine is a partial mu agonist opioid with one-half to one-sixth the parenteral analgesic potency of morphine. The purpose of this study was to characterize the effects of pentazocine in comparison to naloxone (an opioid antagonist), hydromorpho
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(1)
This study was conducted to determine whether the acute administration of bromocriptine, a dopamine agonist, modulates the acute pharmacologic effects of i.v. cocaine in humans. Eight current users of i.v. cocaine who were not seeking treatment for t
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 261(3)
Buprenorphine is an opioid agonist-antagonist being evaluated for treatment of opioid dependence. This study characterized the effects of buprenorphine in comparison to naloxone, hydromorphone and saline, in methadone-dependent volunteers. In a resid