Zobrazeno 1 - 10
of 57
pro vyhledávání: '"E C, Heath"'
Publikováno v:
Journal of Biological Chemistry. 254:4101-4109
Autor:
E C Heath, L A Goldstein
Publikováno v:
Journal of Biological Chemistry. 259:9212-9217
The biosynthesis of rat haptoglobin, a hetrotetrameric glycoprotein (alpha 2 beta 2), requires the post-translational cleavage of its glycosylated primary translation product (prohaptoglobin) into alpha- and beta-subunits (Hanley, J. M., Haugen, T. H
Autor:
T N Oeltmann, E C Heath
Publikováno v:
Journal of Biological Chemistry. 254:1028-1032
The biologic properties of a purified hybrid protein containing the toxic subunit A of ricin and the cell-specific subunit of human chorionic gonadotropin (hCGbeta) in a disulfide conjugate is reported. The biologic activity of the hybrid has been st
Autor:
E C Heath, T N Oeltmann
Publikováno v:
Journal of Biological Chemistry. 254:1022-1027
In order to study the mechanisms involved in the interaction of cell-surface components and effector proteins, we synthesized a double-labeled dimeric hybrid molecule consisting of the toxic A subunit of the lectin ricin and the cell-specific beta su
Autor:
Kathryn M. Verbanac, E C Heath
Publikováno v:
Journal of Biological Chemistry. 261:9979-9989
The Z genetic variant of human alpha 1-antitrypsin (alpha 1AT) is associated with decreased serum alpha 1AT levels, hepatic inclusion bodies, and an increased risk of lung and liver disease. We studied the biosynthesis, processing, and secretion of n
Publikováno v:
The Journal of Clinical Pharmacology. 28:81-87
A randomized, four-way cross-over study was conducted in eight healthy male volunteers to determine the relative and absolute bioavailability of prednisone (PN) and prednisolone (PL). PN and PL were administered as single, oral 10-mg tablet doses and
Publikováno v:
Journal of Biological Chemistry. 252:2372-2383
The biosynthesis and secretion of a glycosylated, K-type immunoglobulin light chain (K-46) was studied in a mouse myeloma tumor, mineral oil plasmacytoma-46B. Viable single cell suspensions were prepared from excised tumors and optimal conditions wer
Autor:
K P Anderson, E C Heath
Publikováno v:
Journal of Biological Chemistry. 260:12065-12071
The rat major acute phase protein (alpha 1-MAP) is a cysteine protease inhibitor. The stoichiometry of the interaction between the inhibitor and enzyme was shown to be 1:2. A cDNA clone specific for rat alpha 1-MAP was isolated from a cDNA library pr
Autor:
G L Firestone, E C Heath
Publikováno v:
Journal of Biological Chemistry. 256:1404-1411
Autor:
T N Oeltmann, E C Heath
Publikováno v:
Journal of Biological Chemistry. 250:8696-8703
A high molecular weight heteropolysaccharide, composed of glucose, glucuronic acid, N-acetylglucosamine, and mannose in an approximate molar ratio of 1:2:2:5, respectively, was isolated from phage K-2 and from the soluble fraction of phage-infected A