Zobrazeno 1 - 10
of 47
pro vyhledávání: '"E C, Haley"'
Autor:
Natalie E. C. Haley, Thomas E. Ouldridge, Ismael Mullor Ruiz, Alessandro Geraldini, Ard A. Louis, Jonathan Bath, Andrew J. Turberfield
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Synthetic molecular systems require subtle control over their thermodynamics and reaction kinetics to implement features such as catalysis. Here the authors propose using mismatches in a DNA duplex to drive catalytic reactions forward whilst maintain
Externí odkaz:
https://doaj.org/article/0e14c3f417da4a58968040c4405b62d2
Autor:
Ismael Mullor Ruiz, Thomas E. Ouldridge, Andrew J. Turberfield, Ard A. Louis, Alessandro Geraldini, Natalie E. C. Haley, Jonathan Bath
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Recent years have seen great advances in the development of synthetic self-assembling molecular systems. Designing out-of-equilibrium architectures, however, requires a more subtle control over the thermodynamics and kinetics of reactions. We propose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6f458cf255b6cb963697df5b1c1523
https://ora.ox.ac.uk/objects/uuid:c2e56147-451c-44e6-8787-b8e11ea35c7c
https://ora.ox.ac.uk/objects/uuid:c2e56147-451c-44e6-8787-b8e11ea35c7c
Autor:
Seham Helmi, Andrew J. Turberfield, Robert D. Schreiber, Florence Benn, Jonathan Bath, Alexandra E. Lucas, Natalie E. C. Haley, Emma Silvester
Publikováno v:
Angewandte Chemie International Edition. 57:7687-7690
We report the design and assembly of chiral DNA nanotubes with well-defined and addressable inside and outside surfaces. We demonstrate that the outside surface can be functionalised with a chiral arrangement of gold nanoparticles to create a plasmon
Autor:
Thomas E. Ouldridge, Jonathan Bath, Andrew J. Turberfield, Robert R. F. Machinek, Natalie E. C. Haley
DNA is used to construct synthetic systems that sense, actuate, move and compute. The operation of many dynamic DNA devices depends on toehold-mediated strand displacement, by which one DNA strand displaces another from a duplex. Kinetic control of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce245f77c998ee84c0762897c19ff37b
https://doi.org/10.1038/ncomms6324
https://doi.org/10.1038/ncomms6324
Autor:
Jonathan Bath, Petr Šulc, John S. Schreck, Jonathan P. K. Doye, Flavio Romano, Andrew J. Turberfield, Thomas E. Ouldridge, Ard A. Louis, R. F. Machinek, Natalie E. C. Haley
Publikováno v:
IET/SynbiCITE Engineering Biology Conference.
Autor:
E. C. Haley, C. A. Lewandowski, John R. Marler, T. G. Brott, M. Lu, J. C. Grotta, P. C. Lyden, Joseph P. Broderick, S. H. Horowitz, T. P. Kwiatkowski, B. C. Tilley, Steven R. Levine, M. P. Frankel
Publikováno v:
Neurology. 55:1649-1655
Background: The National Institute of Neurological Disorders and Stroke (NINDS) rt-PA Stroke Study showed a similar percentage of intracranial hemorrhage and good outcome in patients 3 months after stroke treatment given 0 to 90 minutes and 91 to 180
Publikováno v:
Stroke. 31:940-945
Background and Purpose —We investigated the combined effect of tissue plasminogen activator and ischemia on middle cerebral artery (MCA) reactivity to determine whether abnormal MCA function after 2 hours of ischemia was worse in arteries perfused
Autor:
E. C. Haley, Alfred F. Connors, Karen C. Johnston, Xin-Qun Wang, William A. Knaus, Douglas P. Wagner
Publikováno v:
Stroke. 31:448-455
Background and Purpose —The great variability of outcome seen in stroke patients has led to an interest in identifying predictors of outcome. The combination of clinical and imaging variables as predictors of stroke outcome in a multivariable risk
Autor:
E. C. Haley, Walter J. Koroshetz, Jeffery L Saver, D Homer, Robert J. Wityk, Laura L. Truskowski, Karen C. Johnston
Publikováno v:
Stroke. 30:293-298
Background and Purpose —Reduction in infarct volume is the standard measure of therapeutic success in animal stroke models. Reduction in infarct volume has been advocated as a biological surrogate or auxiliary outcome measure for human stroke clini
Autor:
E. C. Haley, Hanson Sk, Faught Re, Li Jy, Patrick D. Lyden, Karen C. Johnston, Feasby Te, Robert J. Adams
Publikováno v:
Stroke. 29:447-453
Background and Purpose —Medical and neurological complications after acute ischemic stroke may adversely impact outcome and in some cases may be preventable. Limited data exist regarding the frequency of such complications occurring in the first da