Výsledky vyhledávání

Polymorphic differences from normal in the aldosterone synthase gene (CYP11B2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome)

Autor: G C, Inglis, P F, Plouin, E C, Friel, E, Davies, R, Fraser, J M, Connell

Publikováno v: Clinical endocrinology. 54(6)

The hypertension of Conn's syndrome is due to autonomous aldosterone production by a unilateral adrenocortical adenoma. The source of tumour initiation and the reasons for excess aldosterone production as opposed to cortisol are not known, although v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::909734312924027da3d2622af5e85a97
https://pubmed.ncbi.nlm.nih.gov/11422106

Zobrazit plný text záznamu

An influence of variation in the aldosterone synthase gene (CYP11B2) on corticosteroid responses to ACTH in normal human subjects

Autor: E, Davies, C D, Holloway, M C, Ingram, E C, Friel, G C, Inglis, L, Swan, W S, Hillis, R, Fraser, J M, Connell

Publikováno v: Clinical endocrinology. 54(6)

Previous evidence suggests that the efficiency of 11beta-hydroxylase is at least partly heritable and also that it may be mildly impaired in essential hypertension. In both cases, assessment of activity was based on the response of 11-deoxycorticoste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b46efeab83f16ea7be21b7ab2fda4b6f
https://pubmed.ncbi.nlm.nih.gov/11422117

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání