Výsledky vyhledávání - "E C, Dempsey"

Hypoxia-induced pulmonary vascular remodeling: contribution of the adventitial fibroblasts

Autor: K R, Stenmark, D, Bouchey, R, Nemenoff, E C, Dempsey, M, Das

Publikováno v: Physiological research. 49(5)

Vascular repair in response to injury or stress (often referred to as remodeling) is a common complication of many cardiovascular abnormalities including pulmonary hypertension, systemic hypertension, atherosclerosis, vein graft remodeling and resten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30c5e89f2c1bb6c05cdd81e8e5c5b3cc
https://pubmed.ncbi.nlm.nih.gov/11191356

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Angiogenic squamous dysplasia in bronchi of individuals at high risk for lung cancer

Autor: R L, Keith, Y E, Miller, R M, Gemmill, H A, Drabkin, E C, Dempsey, T C, Kennedy, S, Prindiville, W A, Franklin

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(5)

Lung carcinogenesis is assumed to be a multistep process, but detailed understanding of the sequential morphological and molecular changes preceding invasive lung cancer remains elusive. To better understand early lung carcinogenesis, we initiated a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eb4619983ecef15d2eb893f7d7b8d0d0
https://pubmed.ncbi.nlm.nih.gov/10815876

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Hypoxia induces cell-specific changes in gene expression in vascular wall cells: implications for pulmonary hypertension

Autor: K R, Stenmark, M, Frid, R, Nemenoff, E C, Dempsey, M, Das

Publikováno v: Advances in experimental medicine and biology. 474

Mammals respond to reduced oxygen concentrations (hypoxia) in many different ways at the systemic, local, cellular and molecular levels. Within the pulmonary circulation, exposure to chronic hypoxia has been demonstrated to illicit increases in pulmo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::314cae9d7918bd661be6f754d3c8113f
https://pubmed.ncbi.nlm.nih.gov/10635005

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Hypoxic growth of bovine pulmonary artery smooth muscle cells: dependence on synergy, heterogeneity, and injury-induced phenotypic change

Autor: E C, Dempsey, M, Das, M G, Frid, Y, Xu, K R, Stenmark

Publikováno v: Chest. 114

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08b587e32f7fdf5b6d9b621fcd283221
https://pubmed.ncbi.nlm.nih.gov/9676612

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Heterogeneity in the proliferative response of bovine pulmonary artery smooth muscle cells to mitogens and hypoxia: importance of protein kinase C

Autor: E C, Dempsey, M G, Frid, A A, Aldashev, M, Das, K R, Stenmark

Publikováno v: Canadian journal of physiology and pharmacology. 75(7)

Pulmonary artery (PA) smooth muscle cell (SMC) proliferation is an important contributor to the vascular remodeling that occurs in chronic hypoxic pulmonary hypertension. The earliest SMC proliferative changes in response to hypoxia occur in the oute

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9d7b73c7acba745294b94ba76772ad31
https://pubmed.ncbi.nlm.nih.gov/9315363

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High frequency of K-ras codon 12 mutations in bronchoalveolar lavage fluid of patients at high risk for second primary lung cancer

Autor: F M, Scott, R, Modali, T A, Lehman, M, Seddon, K, Kelly, E C, Dempsey, V, Wilson, M S, Tockman, J L, Mulshine

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 3(3)

A high frequency of K-ras mutations may indicate preneoplastic changes in the bronchial epithelium as a result of genotoxic injury. With the use of sensitive detection techniques, we report a higher prevalence of K-ras mutations in bronchoalveolar la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71a86e97964adcd89108b19df922708a
https://pubmed.ncbi.nlm.nih.gov/9815708

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Unique growth properties of neonatal pulmonary vascular cells: importance of time- and site-specific responses, cell-cell interaction, and synergy

Autor: E C, Dempsey, M, Das, M G, Frid, K R, Stenmark

Publikováno v: Journal of perinatology : official journal of the California Perinatal Association. 16(2 Pt 2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1fb4728ee824e58bae45a8a5688f4abb
https://pubmed.ncbi.nlm.nih.gov/8732542

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Pregnancy-stimulated growth of vascular smooth muscle cells: importance of protein kinase C-dependent synergy between estrogen and platelet-derived growth factor

Autor: L E, Keyes, L G, Moore, S J, Walchak, E C, Dempsey

Publikováno v: Journal of cellular physiology. 166(1)

Dramatic smooth muscle cell (SMC) growth occurs in the uterine artery during pregnancy. The potential for pregnancy-associated growth may also exist at other vascular sites. We tested the hypothesis that increased growth of uterine artery SMC isolate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fbf82321c5391f8883eefbbb2c91f6e4
https://pubmed.ncbi.nlm.nih.gov/8557771

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