Zobrazeno 1 - 10
of 63
pro vyhledávání: '"E C, Chew"'
Publikováno v:
Oncology Reports. 4:115-118
Four melanoma cell lines with different metastatic potential were used to study the expression of 67 kD laminin receptor (LnR) gene by traditional immunohistochemistry and polymerase chain reaction techniques. Intensive labeling of LnR protein was fo
Publikováno v:
Oncology reports. 2(6)
MARs (matrix attachment region) and SARs (scaffold attachment region) are fragments of DNA that associated with nuclear matrix and chromosome scaffold even after extensive removal of most of the nuclear proteins and chromatin. The present study showe
Autor:
E. C. Chew, S ChewCheng, Shiyan Wang, Julia Kin-Ming Lee, H Chan, H Yam, S Tsao, C Fan, L Yang
Publikováno v:
Oncology reports. 3(4)
Nuclear matrix is a scaffold-like structure of the nucleus after sequential treatments with detergents, DNase, and high salt buffers. Its involvement in various cellular activities has been emphasised in various studies. In this study, nuclear matrix
Human papillomavirus 16 E6 and E7 are associated with the nuclear matrix of cervical carcinoma cells
Publikováno v:
Oncology reports. 4(3)
Carcinoma of uterine cervix is closely associated with human papillomavirus (HPV) infection and HPV16 DNA has been shown to integrate into the genome of host cancer cells. The subgenomic fragments (E6E7) were found to be present in nuclear matrix (NM
Publikováno v:
Chinese medical journal. 116(1)
To investigate arsenic trioxide (As(2)O(3))-induced apoptosis and the effects on cell nuclear matrix related protein promyelocytic leukaemia (PML).HepG2 cells were cultured in MEM medium and treated with 0.5, 2, 5 and 10 micro mol/L As(2)O(3) for eit
Publikováno v:
Anticancer research. 21(4A)
Anticancer agents interfere with the proliferation and survival of tumor cells by a variety of mechanisms. An important factor in the development of a cytotoxic effect by certain anticancer agents is the localization of drug-induced lesions within th
Publikováno v:
Anticancer research. 21(1A)
Cancer metastasis is a complex multi-step process in which tumor cells leave the primary site and develop a secondary tumor in distant organs. Laminin plays an important role in this process. The expression of laminin in four melanoma cell lines with
Publikováno v:
Anticancer research. 20(3A)
Sixty gliomas obtained by neurosurgical resections were examined. Paraffin blocks were retrieved from pathological files of the Second Affiliated Hospital in Guangzhou Medical College. The methods of argyrophilic technique for AgNORs staining, and Im
Publikováno v:
Anticancer research. 19(6B)
Bcl-2 and Bax proteins are implicated in the regulation of apoptosis. Nuclear matrix has been demonstrated to be associated with a vast array of functional and regulatory properties of cells. NuMA is one member of a class of nuclear matrix proteins t
Publikováno v:
Anticancer research. 19(5B)
Two melanoma cell lines with different metastatic potential were used to study the association of EGFR gene fragments with the nuclear matrix and its role in cancer metastasis by polymerase chain reaction. A 940 bp positive amplification by PCR using