Zobrazeno 1 - 10
of 63
pro vyhledávání: '"E Bridie, Clemens"'
Autor:
Isabelle Jia-Hui Foo, Brendon Y. Chua, E. Bridie Clemens, So Young Chang, Xiaoxiao Jia, Hayley A. McQuilten, Ashley Huey Yiing Yap, Aira F. Cabug, Mitra Ashayeripanah, Hamish E. G. McWilliam, Jose A. Villadangos, Maximilien Evrard, Laura K. Mackay, Linda M. Wakim, John K. Fazakerley, Katherine Kedzierska, Lukasz Kedzierski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Immunity to infectious diseases is predominantly studied by measuring immune responses towards a single pathogen, although co-infections are common. In-depth mechanisms on how co-infections impact anti-viral immunity are lacking, but are hig
Externí odkaz:
https://doaj.org/article/f7573a9c40cb46eebac49bbe854be8df
Autor:
Luca Hensen, Patricia T. Illing, E. Bridie Clemens, Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Nicole A. Mifsud, Andrea T. Nguyen, Christopher Szeto, Brendon Y. Chua, Hanim Halim, Simone Rizzetto, Fabio Luciani, Liyen Loh, Emma J. Grant, Phillipa M. Saunders, Andrew G. Brooks, Steve Rockman, Tom C. Kotsimbos, Allen C. Cheng, Michael Richards, Glen P. Westall, Linda M. Wakim, Thomas Loudovaris, Stuart I. Mannering, Michael Elliott, Stuart G. Tangye, David C. Jackson, Katie L. Flanagan, Jamie Rossjohn, Stephanie Gras, Jane Davies, Adrian Miller, Steven Y. C. Tong, Anthony W. Purcell, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The immunology of Indigenous populations is generally understudied outside the context of diseases that are prevalent in these communities. Here the authors identify prevalence of influenza CD8+ T cell epitopes in an Indigenous Australian population
Externí odkaz:
https://doaj.org/article/a3a6a4c017e544c7b83819f5cde0c3d5
Autor:
Thi H. O. Nguyen, Marios Koutsakos, Carolien E. van de Sandt, Jeremy Chase Crawford, Liyen Loh, Sneha Sant, Ludivine Grzelak, Emma K. Allen, Tim Brahm, E. Bridie Clemens, Maria Auladell, Luca Hensen, Zhongfang Wang, Simone Nüssing, Xiaoxiao Jia, Patrick Günther, Adam K. Wheatley, Stephen J. Kent, Malet Aban, Yi-Mo Deng, Karen L. Laurie, Aeron C. Hurt, Stephanie Gras, Jamie Rossjohn, Jane Crowe, Jianqing Xu, David Jackson, Lorena E. Brown, Nicole La Gruta, Weisan Chen, Peter C. Doherty, Stephen J. Turner, Tom C. Kotsimbos, Paul G. Thomas, Allen C. Cheng, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The immunological parameters that define severe influenza disease are not clear within human real time infections. Here the authors compare a severe influenza infection cohort with an influenza vaccinated cohort to understand correlates of severe inf
Externí odkaz:
https://doaj.org/article/2bb8c377813f4ec9954ac0d874794b8f
Autor:
Luca Hensen, Patricia T. Illing, Louise C. Rowntree, Jane Davies, Adrian Miller, Steven Y. C. Tong, Jennifer R. Habel, Carolien E. van de Sandt, Katie L. Flanagan, Anthony W. Purcell, Katherine Kedzierska, E. Bridie Clemens
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CD8+ T cells are a pivotal part of the immune response to viruses, playing a key role in disease outcome and providing long-lasting immunity to conserved pathogen epitopes. Understanding CD8+ T cell immunity in humans is complex due to CD8+ T cell re
Externí odkaz:
https://doaj.org/article/40bc92ca3dce4621aa819f73d956338b
Autor:
Jennifer R Habel, Andrea T Nguyen, Louise C Rowntree, Christopher Szeto, Nicole A Mifsud, E Bridie Clemens, Liyen Loh, Weisan Chen, Steve Rockman, Jane Nelson, Jane Davies, Adrian Miller, Steven Y C Tong, Jamie Rossjohn, Stephanie Gras, Anthony W Purcell, Luca Hensen, Katherine Kedzierska, Patricia T Illing
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010337 (2022)
HLA-A*11:01 is one of the most prevalent human leukocyte antigens (HLAs), especially in East Asian and Oceanian populations. It is also highly expressed in Indigenous people who are at high risk of severe influenza disease. As CD8+ T cells can provid
Externí odkaz:
https://doaj.org/article/d0c943477ace407cbd0292ca6addc93a
Autor:
Wuji Zhang, Lukasz Kedzierski, Brendon Y. Chua, Mark Mayo, Claire Lonzi, Vanessa Rigas, Bianca F. Middleton, Hayley A. McQuilten, Louise C. Rowntree, Lilith F. Allen, Ruth A. Purcell, Hyon-Xhi Tan, Jan Petersen, Priyanka Chaurasia, Francesca Mordant, Mikhail V. Pogorelyy, Anastasia A. Minervina, Jeremy Chase Crawford, Griffith B. Perkins, Eva Zhang, Stephanie Gras, E. Bridie Clemens, Jennifer A. Juno, Jennifer Audsley, David S. Khoury, Natasha E. Holmes, Irani Thevarajan, Kanta Subbarao, Florian Krammer, Allen C. Cheng, Miles P. Davenport, Branka Grubor-Bauk, P. Toby Coates, Britt Christensen, Paul G. Thomas, Adam K. Wheatley, Stephen J. Kent, Jamie Rossjohn, Amy W. Chung, John Boffa, Adrian Miller, Sarah Lynar, Jane Nelson, Thi H. O. Nguyen, Jane Davies, Katherine Kedzierska
Publikováno v:
Nature Immunology. 24:966-978
High-risk groups, including Indigenous people, are at risk of severe COVID-19. Here we found that Australian First Nations peoples elicit effective immune responses to COVID-19 BNT162b2 vaccination, including neutralizing antibodies, receptor-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687eb3e117b7120bc5b62d23f3ec5cd7
https://doi.org/10.1038/s41590-023-01508-y
https://doi.org/10.1038/s41590-023-01508-y
Autor:
Emma J. Grant, Tracy M. Josephs, Liyen Loh, E. Bridie Clemens, Sneha Sant, Mandvi Bharadwaj, Weisan Chen, Jamie Rossjohn, Stephanie Gras, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Mutations within immunological epitope containing regions of influenza A virus can impair the established immune response between influenza strains and could impact rational vaccine design. Here Grant et al. examine the presence, structural impact an
Externí odkaz:
https://doaj.org/article/e3208577560a455ba744a1baab24971d
Autor:
Zhongfang Wang, Lingyan Zhu, Thi H. O. Nguyen, Yanmin Wan, Sneha Sant, Sergio M. Quiñones-Parra, Jeremy Chase Crawford, Auda A. Eltahla, Simone Rizzetto, Rowena A. Bull, Chenli Qiu, Marios Koutsakos, E. Bridie Clemens, Liyen Loh, Tianyue Chen, Lu Liu, Pengxing Cao, Yanqin Ren, Lukasz Kedzierski, Tom Kotsimbos, James M. McCaw, Nicole L. La Gruta, Stephen J. Turner, Allen C. Cheng, Fabio Luciani, Xiaoyan Zhang, Peter C. Doherty, Paul G. Thomas, Jianqing Xu, Katherine Kedzierska
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Virus-specific CD8+ T cells are crucial during H7N9 influenza infection, but CD8+ T cell dysfunction is associated with poor prognosis. Here, the authors use molecular and phenotypic analysis to establish persistence of clonally diverse CD8+ T cell p
Externí odkaz:
https://doaj.org/article/0354e26df1f7459caf4dc1fcf140649a
Autor:
Mikhail Goncharov, Dmitry Bagaev, Dmitrii Shcherbinin, Ivan Zvyagin, Dmitry Bolotin, Paul G. Thomas, Anastasia A. Minervina, Mikhail V. Pogorelyy, Kristin Ladell, James E. McLaren, David A. Price, Thi H. O. Nguyen, Louise C. Rowntree, E. Bridie Clemens, Katherine Kedzierska, Garry Dolton, Cristina Rafael Rius, Andrew Sewell, Jerome Samir, Fabio Luciani, Ksenia V. Zornikova, Alexandra A. Khmelevskaya, Saveliy A. Sheetikov, Grigory A. Efimov, Dmitry Chudakov, Mikhail Shugay
Publikováno v:
Nature methods. 19(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4611b92062633cafb9aac1d7696c6a83
https://pubmed.ncbi.nlm.nih.gov/35970936
https://pubmed.ncbi.nlm.nih.gov/35970936
Autor:
Thi H.O. Nguyen, Louise C. Rowntree, Lilith F. Allen, Brendon Y. Chua, Lukasz Kedzierski, Chhay Lim, Masa Lasica, G. Surekha Tennakoon, Natalie R. Saunders, Megan Crane, Lynette Chee, John F. Seymour, Mary Ann Anderson, Ashley Whitechurch, E. Bridie Clemens, Wuji Zhang, So Young Chang, Jennifer R. Habel, Xiaoxiao Jia, Hayley A. McQuilten, Anastasia A. Minervina, Mikhail V. Pogorelyy, Priyanka Chaurasia, Jan Petersen, Tejas Menon, Luca Hensen, Jessica A. Neil, Francesca L. Mordant, Hyon-Xhi Tan, Aira F. Cabug, Adam K. Wheatley, Stephen J. Kent, Kanta Subbarao, Theo Karapanagiotidis, Han Huang, Lynn K. Vo, Natalie L. Cain, Suellen Nicholson, Florian Krammer, Grace Gibney, Fiona James, Janine M. Trevillyan, Jason A. Trubiano, Jeni Mitchell, Britt Christensen, Katherine A. Bond, Deborah A. Williamson, Jamie Rossjohn, Jeremy Chase Crawford, Paul G. Thomas, Karin A. Thursky, Monica A. Slavin, Constantine S. Tam, Benjamin W. Teh, Katherine Kedzierska
Publikováno v:
Cell Reports Medicine. 4:101017
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5567fd7ce72ce594e3e3672ddd222cf
https://doi.org/10.1016/j.xcrm.2023.101017
https://doi.org/10.1016/j.xcrm.2023.101017