Zobrazeno 1 - 10
of 53
pro vyhledávání: '"E Bonnem"'
Autor:
B Poiesz, E Bonnem, L C Bartos, M L Maliszewski, W D Lawrence, Gene D. Morse, J Santora, Ross G. Hewitt
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:512-522
Granulocytopenia is a complication of human immunodeficiency virus disease, as well as a toxic manifestation of zidovudine therapy. To evaluate pharmacokinetic and pharmacodynamic relationships, 11 AIDS-AIDS-related complex patients who had developed
Autor:
E. Bonnem, H. Ozer, L. Tensen, Harvey M. Golomb, J. Thompson, James W. Vardiman, A. Fefer, J. S. Burke, C. Portlock, R. Silber, Mark J. Ratain, J. Rappeport, R. Spiegel, David W. Golde
Publikováno v:
Leukemia & Lymphoma. 4:99-102
One hundred ninety-five patients were entered into a multi-institutional study of interferon alfa 2b from 1983-1986; follow-up was completed through June 1989. A complete remission was documented in 7 patients, a partial remission in 152 patients, a
Autor:
G J, Lieschke, D, Maher, M, O'Connor, M, Green, W, Sheridan, M, Rallings, E, Bonnem, A W, Burgess, K, McGrath, R M, Fox
Publikováno v:
Cancer research. 50(3)
A Phase I study of bacterially synthesized recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) was undertaken in 21 patients with advanced malignancy or neutropenia. rhGM-CSF was administered once daily by i.v. bolus injecti
Autor:
E. Bonnem, P. von Wussow
Publikováno v:
Interferone ISBN: 9783642933844
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2ba5f78e92cf7d50d2d3590af17007e
https://doi.org/10.1007/978-3-642-93383-7_23
https://doi.org/10.1007/978-3-642-93383-7_23
Publikováno v:
Nuclear Physics. 63:513-519
The calculated binding energies and r.m.s. radii are given for the ground states of the three and four-nucleon systems for nine assumed central potentials. Two of the potentials have hard cores and six have velocity-dependent terms. The results are g
Autor:
H M, Golomb, A, Fefer, D W, Golde, H, Ozer, C, Portlock, R, Silber, J, Rappeport, M J, Ratain, J, Thompson, E, Bonnem
Publikováno v:
Seminars in oncology. 15(5 Suppl 5)
Autor:
B M, Boman, M M, Gagen, E, Bonnem, J A, Ajani, S, Schmidt, I W, Dimery, J, Golando, J, Neidhart
Publikováno v:
Journal of biological response modifiers. 7(5)
A Phase I study of recombinant gamma-interferon was conducted in 35 patients with advanced malignancy. The schedule was twice weekly administered intravenously. Patients were assigned to six dose levels. The major toxicities were flu-like symptoms an
Autor:
K, Foon, J, Doroshow, E, Bonnem, A, Fefer, S, Graham, B, Grosh, P, Narayan, L, Elias, H, Harvey, R, Schulof
Publikováno v:
Journal of biological response modifiers. 7(6)
Eighty-nine patients with advanced measurable metastatic renal cell carcinoma were entered into a prospective randomized trial comparing alpha-interferon to gamma-interferon and to the combination. The trial was performed in order to confirm the acti
Autor:
D C, Case, H L, Sonneborn, S D, Paul, J, Hiebel, M A, Boyd, M A, Shepp, B M, Dorsk, E, Bonnem
Publikováno v:
Cancer treatment reports. 70(11)
Twenty previously treated patients with multiple myeloma were treated with rDNA human alpha-2 interferon (INTRON A) in a phase II trial. Patients received an induction phase of therapy consisting of 3-100 X 10(6) IU/m2 iv given every other day pendin
Publikováno v:
Seminars in oncology. 13(3 Suppl 2)
Preclinical studies have suggested combination therapy with interferon and radiation results in an enhanced cytotoxic effect. Both additive and synergistic effects have been reported in mammalian cells in tissue culture. A phase I trial was designed