Zobrazeno 1 - 10
of 146
pro vyhledávání: '"E Birgitte Lane"'
Autor:
Aileen Sandilands, Frances J D Smith, Declan P Lunny, Linda E Campbell, Kirsty M Davidson, Stephanie F MacCallum, Laura D Corden, Lesley Christie, Stewart Fleming, E Birgitte Lane, W H Irwin McLean
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64404 (2013)
Keratin 7 (K7) is a Type II member of the keratin superfamily and despite its widespread expression in different types of simple and transitional epithelia, its functional role in vivo remains elusive, in part due to the lack of any appropriate mouse
Externí odkaz:
https://doaj.org/article/28afc97ae05f4a86a617ab1c7711baae
Autor:
Daniel R Beriault, Oualid Haddad, John V McCuaig, Zachary J Robinson, David Russell, E Birgitte Lane, Douglas S Fudge
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31320 (2012)
Epidermolysis bullosa simplex (EBS) is an inherited skin-blistering disease that is caused by dominant mutations in the genes for keratin K5 or K14 proteins. While the link between keratin mutations and keratinocyte fragility in EBS patients is clear
Externí odkaz:
https://doaj.org/article/ac2d745afb3c455db0455d2e0de04a2c
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2327 (2008)
The prevailing model of the mechanical function of intermediate filaments in cells assumes that these 10 nm diameter filaments make up networks that behave as entropic gels, with individual intermediate filaments never experiencing direct loading in
Externí odkaz:
https://doaj.org/article/d262d60cc5a14b2b85bbdc9f5d9d392c
Autor:
Cedric Badowski, Tong San Tan, Teimur Aliev, David Trudil, Maria Larina, Viсtoria Argentova, Muhammad Jasrie Firdaus, Paula Benny, Vivien S.T. Woo, E. Birgitte Lane
Publikováno v:
JID Innovations, Vol 2, Iss 2, Pp 100096- (2022)
Epidermolysis bullosa is a group of severe skin blistering disorders, which currently have no cure. The pathology of epidermolysis bullosa is recognized as having an inflammatory component, but the role of inflammation in different epidermolysis bull
Externí odkaz:
https://doaj.org/article/1f3f8a32ff68444688d6a6207c54b3c5
Publikováno v:
FASEB BioAdvances. 4:631-637
Organotypic skin cultures represent in vitro models of skin which can be used for disease modeling, tissue engineering, and screening applications. Non-human collagen is currently the gold standard material used for the construction of the supporting
Autor:
Judith B. Fülle, Rogerio Alves de Almeida, Craig Lawless, Bian Yanes, E. Birgitte Lane, David R. Garrod, Christoph Ballestrem
Desmosomes are multiprotein adhesion complexes that link intermediate filaments to the plasma membrane, ensuring the mechanical integrity of cells across tissues, but how they participate in the wider signalling network to exert their full function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b6df79d02ba01b6e4b79c3026310b8
https://doi.org/10.1101/2023.03.24.534085
https://doi.org/10.1101/2023.03.24.534085
Autor:
Yi Zhen Ng, Heming Wei, Leong Kin Fon, E. Birgitte Lane, Inne Arline Diana, Priya Bishnoi, Declan P. Lunny, Srie Prihianti Gondokaryono, Mark Jean Aan Koh, Ene-Choo Tan, X.F. Colin C. Wong, John E.A. Common
Publikováno v:
American Journal of Medical Genetics Part A. 185:625-630
Self-improving dystrophic epidermolysis bullosa is a rare subtype of dystrophic epidermolysis bullosa (DEB) characterized by significant improvement in skin fragility within the first few years of life. Genetic inheritance has previously been reporte
Desmosome dualism – most of the junction is stable, but a plakophilin moiety is persistently dynamic
Autor:
David Liebl, Graham D. Wright, Christoph Ballestrem, David R Garrod, Jaron Liu, Rogerio Alves de Almeida, Henri Huppert, Bian Yanes, E. Birgitte Lane, Judith B Fülle
Publikováno v:
J Cell Sci
Desmosomes, strong cell–cell junctions of epithelia and cardiac muscle, link intermediate filaments to cell membranes and mechanically integrate cells across tissues, dissipating mechanical stress. They comprise five major protein classes – desmo
Autor:
Cedric Badowski, Tong San Tan, Teimur Aliev, David Trudil, Maria Larina, Viсtoria Argentova, Muhammad Jasrie Firdaus, Paula Benny, Vivien S.T. Woo, E. Birgitte Lane
Publikováno v:
JID innovations : skin science from molecules to population health. 2(2)
Epidermolysis bullosa is a group of severe skin blistering disorders, which currently have no cure. The pathology of epidermolysis bullosa is recognized as having an inflammatory component, but the role of inflammation in different epidermolysis bull
Autor:
John Soon Yew Lim, E. Birgitte Lane, Cedric Badowski, Steven S. Leonardi, John E.A. Common, Muhammad Jasrie Firdaus, Tong San Tan
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
In the skin fragility disorder epidermolysis bullosa simplex (EBS), mutations in keratin 14 (K14, also known as KRT14) or keratin 5 (K5, also known as KRT5) lead to keratinocyte rupture and skin blistering. Severe forms of EBS are associated with cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726b85456909374f01d59aeb8a29a6d7
https://hdl.handle.net/10356/153607
https://hdl.handle.net/10356/153607