Zobrazeno 1 - 10
of 147
pro vyhledávání: '"E Birgitte Lane"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract Arrhythmogenic cardiomyopathy (AC) is a common cause of sudden cardiac arrest and death in young adults. It can be induced by different types of mutations throughout the desmoplakin gene including the R2834H mutation in the extreme carboxyte
Externí odkaz:
https://doaj.org/article/b62ebef847be48b89fd25aa85fbf286b
Autor:
Aileen Sandilands, Frances J D Smith, Declan P Lunny, Linda E Campbell, Kirsty M Davidson, Stephanie F MacCallum, Laura D Corden, Lesley Christie, Stewart Fleming, E Birgitte Lane, W H Irwin McLean
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64404 (2013)
Keratin 7 (K7) is a Type II member of the keratin superfamily and despite its widespread expression in different types of simple and transitional epithelia, its functional role in vivo remains elusive, in part due to the lack of any appropriate mouse
Externí odkaz:
https://doaj.org/article/28afc97ae05f4a86a617ab1c7711baae
Autor:
Daniel R Beriault, Oualid Haddad, John V McCuaig, Zachary J Robinson, David Russell, E Birgitte Lane, Douglas S Fudge
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31320 (2012)
Epidermolysis bullosa simplex (EBS) is an inherited skin-blistering disease that is caused by dominant mutations in the genes for keratin K5 or K14 proteins. While the link between keratin mutations and keratinocyte fragility in EBS patients is clear
Externí odkaz:
https://doaj.org/article/ac2d745afb3c455db0455d2e0de04a2c
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2327 (2008)
The prevailing model of the mechanical function of intermediate filaments in cells assumes that these 10 nm diameter filaments make up networks that behave as entropic gels, with individual intermediate filaments never experiencing direct loading in
Externí odkaz:
https://doaj.org/article/d262d60cc5a14b2b85bbdc9f5d9d392c
Autor:
Rókus Kriszt, Satoshi Arai, Hideki Itoh, Michelle H. Lee, Anna G. Goralczyk, Xiu Min Ang, Aaron M. Cypess, Andrew P. White, Farnaz Shamsi, Ruidan Xue, Jung Yeol Lee, Sung-Chan Lee, Yanyan Hou, Tetsuya Kitaguchi, Thankiah Sudhaharan, Shin’ichi Ishiwata, E. Birgitte Lane, Young-Tae Chang, Yu-Hua Tseng, Madoka Suzuki, Michael Raghunath
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The identification of brown adipose deposits in adults has led to significant interest in targeting this metabolically active tissue for treatment of obesity and diabetes. Improved methods for the direct measurement of heat production as the
Externí odkaz:
https://doaj.org/article/52a314579272494397c0203168538870
Publikováno v:
FASEB BioAdvances. 4:631-637
Organotypic skin cultures represent in vitro models of skin which can be used for disease modeling, tissue engineering, and screening applications. Non-human collagen is currently the gold standard material used for the construction of the supporting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f7138361e700fa8802d741d3f38604
https://doi.org/10.1096/fba.2022-00026
https://doi.org/10.1096/fba.2022-00026
Autor:
Judith B. Fülle, Rogerio Alves de Almeida, Craig Lawless, Bian Yanes, E. Birgitte Lane, David R. Garrod, Christoph Ballestrem
Desmosomes are multiprotein adhesion complexes that link intermediate filaments to the plasma membrane, ensuring the mechanical integrity of cells across tissues, but how they participate in the wider signalling network to exert their full function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b6df79d02ba01b6e4b79c3026310b8
https://doi.org/10.1101/2023.03.24.534085
https://doi.org/10.1101/2023.03.24.534085
Autor:
Yi Zhen Ng, Heming Wei, Leong Kin Fon, E. Birgitte Lane, Inne Arline Diana, Priya Bishnoi, Declan P. Lunny, Srie Prihianti Gondokaryono, Mark Jean Aan Koh, Ene-Choo Tan, X.F. Colin C. Wong, John E.A. Common
Publikováno v:
American Journal of Medical Genetics Part A. 185:625-630
Self-improving dystrophic epidermolysis bullosa is a rare subtype of dystrophic epidermolysis bullosa (DEB) characterized by significant improvement in skin fragility within the first few years of life. Genetic inheritance has previously been reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0abda5af056a857f2eae2da009abfc04
https://doi.org/10.1002/ajmg.a.61975
https://doi.org/10.1002/ajmg.a.61975
Desmosome dualism – most of the junction is stable, but a plakophilin moiety is persistently dynamic
Autor:
David Liebl, Graham D. Wright, Christoph Ballestrem, David R Garrod, Jaron Liu, Rogerio Alves de Almeida, Henri Huppert, Bian Yanes, E. Birgitte Lane, Judith B Fülle
Publikováno v:
J Cell Sci
Desmosomes, strong cell–cell junctions of epithelia and cardiac muscle, link intermediate filaments to cell membranes and mechanically integrate cells across tissues, dissipating mechanical stress. They comprise five major protein classes – desmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f724e5c4e47da3aeae0274a15ca96a8a
https://doi.org/10.1242/jcs.258906
https://doi.org/10.1242/jcs.258906
Autor:
Cedric Badowski, Tong San Tan, Teimur Aliev, David Trudil, Maria Larina, Viсtoria Argentova, Muhammad Jasrie Firdaus, Paula Benny, Vivien S.T. Woo, E. Birgitte Lane
Publikováno v:
JID innovations : skin science from molecules to population health. 2(2)
Epidermolysis bullosa is a group of severe skin blistering disorders, which currently have no cure. The pathology of epidermolysis bullosa is recognized as having an inflammatory component, but the role of inflammation in different epidermolysis bull
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77bd4c6a0b71d090807cbd9765db06a
https://pubmed.ncbi.nlm.nih.gov/35265936
https://pubmed.ncbi.nlm.nih.gov/35265936