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Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC) : an open-label, platform-adaptive randomised controlled trial

Autor: Christopher C Butler, F D Richard Hobbs, Oghenekome A Gbinigie, Najib M Rahman, Gail Hayward, Duncan B Richards, Jienchi Dorward, David M Lowe, Joseph F Standing, Judith Breuer, Saye Khoo, Stavros Petrou, Kerenza Hood, Jonathan S Nguyen-Van-Tam, Mahendra G Patel, Benjamin R Saville, Joe Marion, Emma Ogburn, Julie Allen, Heather Rutter, Nick Francis, Nicholas P B Thomas, Philip Evans, Melissa Dobson, Tracie-Ann Madden, Jane Holmes, Victoria Harris, May Ee Png, Mark Lown, Oliver van Hecke, Michelle A Detry, Christina T Saunders, Mark Fitzgerald, Nicholas S Berry, Lazaro Mwandigha, Ushma Galal, Sam Mort, Bhautesh D Jani, Nigel D Hart, Haroon Ahmed, Daniel Butler, Micheal McKenna, Jem Chalk, Layla Lavallee, Elizabeth Hadley, Lucy Cureton, Magdalena Benysek, Monique Andersson, Maria Coates, Sarah Barrett, Clare Bateman, Jennifer C Davies, Ivy Raymundo-Wood, Andrew Ustianowski, Andrew Carson-Stevens, Ly-Mee Yu, Paul Little, Akosua A Agyeman, Tanveer Ahmed, Damien Allcock, Adrian Beltran-Martinez, Oluseye E Benedict, Nigel Bird, Laura Brennan, Julianne Brown, Gerard Burns, Mike Butler, Zelda Cheng, Ruth Danson, Nigel de Kare-Silver, Devesh Dhasmana, Jon Dickson, Serge Engamba, Stacey Fisher, Robin Fox, Eve Frost, Richard Gaunt, Sarit Ghosh, Ishtiaq Gilkar, Anna Goodman, Steve Granier, Aleksandra Howell, Iqbal Hussain, Simon Hutchinson, Marie Imlach, Greg Irving, Nicholas Jacobsen, James Kennard, Umar Khan, Kyle Knox, Christopher Krasucki, Tom Law, Rem Lee, Nicola Lester, David Lewis, James Lunn, Claire I. Mackintosh, Mehul Mathukia, Patrick Moore, Seb Morton, Daniel Murphy, Rhiannon Nally, Chinonso Ndukauba, Olufunto Ogundapo, Henry Okeke, Amit Patel, Kavil Patel, Ruth Penfold, Satveer Poonian, Olajide Popoola, Alexander Pora, Vibhore Prasad, Rishabh Prasad, Omair Razzaq, Scot Richardson, Simon Royal, Afsana Safa, Satash Sehdev, Tamsin Sevenoaks, Divya Shah, Aadil Sheikh, Vanessa Short, Baljinder S Sidhu, Ivor Singh, Yusuf Soni, Chris Thalasselis, Pete Wilson, David Wingfield, Michael Wong, Maximillian N J Woodall, Nick Wooding, Sharon Woods, Joanna Yong, Francis Yongblah, Azhar Zafar

Publikováno v: PANORAMIC Trial Collaborative Group, Butler, C C, Hobbs, F D R, Gbinigie, O A, Rahman, N M, Hayward, G, Richards, D B, Dorward, J, Lowe, D M, Standing, J F, Breuer, J, Khoo, S, Petrou, S, Hood, K, Nguyen-Van-Tam, J S, Patel, M G, Saville, B R, Marion, J, Ogburn, E, Allen, J, Rutter, H, Francis, N, Thomas, N P B, Evans, P, Dobson, M, Madden, T-A, Holmes, J, Harris, V, Png, M E, Lown, M, van Hecke, O, Detry, M A, Saunders, C T, Fitzgerald, M, Berry, N S, Mwandigha, L, Galal, U, Mort, S, Jani, B D, Hart, N D, Ahmed, H, Butler, D, McKenna, M, Chalk, J, Lavallee, L, Hadley, E, Cureton, L, Benysek, M, Andersson, M, Coates, M & Barrett, S 2023, ' Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial ', The Lancet, vol. 401, no. 10373, pp. 281-293 . https://doi.org/10.1016/S0140-6736(22)02597-1

Background The safety, effectiveness, and cost-effectiveness of molnupiravir, an oral antiviral medication for SARS-CoV-2, has not been established in vaccinated patients in the community at increased risk of morbidity and mortality from COVID-19. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6937dbf90341fd2ff687fe41c3d612
https://hdl.handle.net/10023/27412

Using lesson study to change teacher knowledge and practice: The role of knowledge sources in teacher change

Autor: Amber E. Benedict, Jessica Williams, Mary T. Brownell, Lindsey Chapman, Alexandria Sweers, Hyojong Sohn

Publikováno v: Teaching and Teacher Education. 122:103951

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ce957965933700068e22c1820e2a0be
https://doi.org/10.1016/j.tate.2022.103951

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Effects of Fatigue on the BTrackS Balance Test for Concussion Management

Autor: Ryan Byron-Fields, Harsimran S. Baweja, Daniel J. Goble, Jeffrey W. Hinshaw, Scott E. Benedict

Publikováno v: International Journal of Athletic Therapy and Training. 22:23-28

Fatigue has been shown to adversely affect balance results, as measured by the Balance Error Scoring System (BESS). The present study aimed to determine whether a new low-cost force plate for concussion balance assessment, the Balance Tracking System

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c34527184fbf2e3d2165301f5adbde2f
https://doi.org/10.1123/ijatt.2016-0086