Zobrazeno 1 - 10
of 79
pro vyhledávání: '"E B, Rodriguez de Turco"'
Publikováno v:
Journal of Neurochemistry. 81:101-105
Here we explored the mechanisms of secretory phospholipase A2 (sPLA2) and glutamate (glu) in neuronal signalling and cell damage. Rats or primary neuronal cultures were treated with MK-801 and injected with/exposed to sPLA2 or glu. MK-801 partially i
Autor:
M. E. Carey, Nilda Parkins, Nicolas G. Bazan, E B Rodriguez de Turco, P. Homayoun, J. Soblosky
Publikováno v:
Neurochemical Research. 25:269-276
Neurotrauma activates the release of membrane phospholipid-derived second messengers, such as free arachidonic acid (20:4n-6, AA) and diacylglycerols (DAGs). In the present study, we analyze the effect of cortical impact injury of low-grade severity
Publikováno v:
Journal of Neurotrauma. 12:791-814
Membrane lipid-derived second messengers are generated by phospholipase A2 (PLA2) during synaptic activity. Overstimulation of this enzyme during neurotrauma results in the accumulation of bioactive metabolites such as arachidonic acid, oxygenated de
Publikováno v:
Journal of Neurochemistry. 61:1835-1842
Cerebral blood flow and oxygenation increase during the early seizures of a series, but the increase in cerebral blood flow attenuates during late seizures, sometimes resulting in decreased cortical oxygenation. Cortical free fatty acids (FFA) and di
Publikováno v:
Journal of Neurochemistry. 61:1438-1444
The effect of Ginkgo biloba extract (EGb 761) treatment (100 mg/kg/day, per os, for 14 days) on electroconvulsive shock (ECS)-induced accumulation of free fatty acids (FFA) and diacylglycerols (DAG) was analyzed in rat cerebral cortex and hippocampus
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 71:690-698
Docosahexaenoic acid (22:6n−3) esterified into phospholipids represents by far the most prevalent fatty acid of rod photoreceptor disc membranes and synaptic terminals. During synaptogenesis and photoreceptor biogenesis, plasma lipoproteins, secret
Publikováno v:
Current Eye Research. 11:73-83
The involvement of retinal pigment epithelial (RPE) cells in the recycling of docosahexaenoic acid (DHA), from phagocytized disc membranes back to the retina, was studied in frogs subsequent to injection of [3H]DHA via the dorsal lymph sac. Rod outer
Publikováno v:
The Journal of Neuroscience. 11:3667-3678
The uptake, metabolism, and cellular distribution of 3H-docosahexaenoic acid (3H-22:6) in the frog retina during in vitro incubation were studied. An initial diffuse labeling throughout the retina was detected by autoradiography and was followed by a
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1093:216-222
The activity of phosphatidylinositol (PI) kinase and the content and fatty acid composition of inositol phospholipids (IPLs) were analyzed in the livers of rats that had been continuously infused with Escherichia coli endotoxin (ET) or saline for 30