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pro vyhledávání: '"E B, Fryar"'
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 53(3)
These studies were designed to develop procedures that would capitalize on the growth inhibitory effects of tamoxifen (Tam) and methotrexate (MTX) in breast cancer, while protecting bone marrow with a priming dose of 5-fluorouracil (5-FU). High-dose
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 49(7)
Faslodex (FAS, ICI 182, 780), a novel steroidal estrogen antagonist decreased high-dose methotrexate (MTX) cytotoxicity in MCF-7 breast cancer cells. When FAS is given at least 24 hr prior to MTX, the resultant interaction is antagonistic. However, w