Zobrazeno 1 - 10 of 55 pro vyhledávání: '"E B, Dowdle"'
1
Site-directed mutagenesis of the synthetic Erythrina trypsin/tissue plasminogen activator (tPA) inhibitor encoding-gene to compare the interaction of Erythrina and soybean trypsin inhibitor with tPA
Autor: A V, Teixeira, E B, Dowdle, D P, Botes
Publikováno v: Biochimica et biophysica acta. 1217(1)
Erythrina trypsin inhibitor (ETI) has good structural and sequence homology with soybean trypsin inhibitor (STI). However, STI does not inhibit tPA. From the three-dimensional structure of ETI it was known that the N-terminus of the molecule forms a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55fee7574ad92203bee80a35e9ef66f5
https://pubmed.ncbi.nlm.nih.gov/8286412
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2
Synthesis and expression of a gene coding for Erythrina trypsin inhibitor (ETI)
Autor: A V, Teixeira, E B, Dowdle, D P, Botes
Publikováno v: Biochimica et biophysica acta. 1217(1)
A gene coding for Erythrina trypsin inhibitor (ETI) was designed, based on the published N-terminal sequence of the protein, and synthesized by an oligonucleotide-directed single strand break-repair mechanism. Direct expression from the expression ve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::02aaed946381a1d9259e5663252a9bc8
https://pubmed.ncbi.nlm.nih.gov/8286411
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3
Processing of HLA-class II invariant chain and expression of the p35 form is different in malignant and transformed cells
Autor: H, Veenstra, P, Jacobs, E B, Dowdle
Publikováno v: Blood. 82(8)
A monoclonal antibody VCD-1, directed against the N-terminal intracellular part of the invariant chain (li) was used to show, by immunoprecipitation and Western blotting, the unprocessed and processed forms of li in chronic lymphocytic leukemia (CLL)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f82616461a085c20586ba508da90c39c
https://pubmed.ncbi.nlm.nih.gov/8400296
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4
Genetic polymorphism of the beta-2 adrenergic receptor in atopic and non-atopic subjects
Autor: M. Martin, Paul C. Potter, L. Van Wyk, E. B. Dowdle, K. U. Lentes
Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 23(10)
Summary To investigate a possible genetic basis for reported differences in β-2 receptor expression in atopic subjects, DNA from 42 atopic children (22 asthmatics and 22 with allergic rhinitis) and 30 non-atopic subjects was Southern blotted and Ban
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3a2e0c68c60e9463639dd7a01703b1
https://pubmed.ncbi.nlm.nih.gov/10780896
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5
Absence of functional inhibition of cloned human beta 2-adrenergic receptors by autoantibodies in asthmatic subjects
Autor: E. B. Dowdle, F. Z. Chung, B. S. Dakers, L. Van Wyk, D. White, Paul C. Potter
Publikováno v: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 23(3)
Using guinea-pig lung membranes and cloned human beta 2-receptor adrenergic receptors the effects of whole serum, plasma, purified immunoglobulins and cellular activation products on beta 2-adrenergic receptor ligand binding and function were investi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12175799dbb0e228d1c8252a8f310f42
https://pubmed.ncbi.nlm.nih.gov/8097132
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6
Fibroblast-dependent tumorigenicity of melanoma xenografts in athymic mice
Autor: E. L. Wilson, E. B. Dowdle, M. F. R. M. Gartner
Publikováno v: International journal of cancer. 51(5)
Two human melanoma cell lines, UCT-Mel 2 and UCT-Mel 3, were invariably tumorigenic in nude mice when inoculated s.c. in doses of 106 cells or higher; 105 cells or less did not give rise to tumours. In this report we show that otherwise sub-tumorigen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed17dd62c83b61152a8148b025735f1
https://pubmed.ncbi.nlm.nih.gov/1612785
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8
The Erythrina protease inhibitor: interactions with tissue plasminogen activator
Autor: C, Heussen-Schemmer, E H, Merrifield, E B, Dowdle
Publikováno v: Thrombosis and haemostasis. 66(2)
The Kunitz-type trypsin and tissue plasminogen activator (t-PA)-inhibitor from Erythrina caffra seeds was cleaved by trypsin at low pH to yield a disulphide linked two-chain molecule with reduced hydrophobicity. This change was used to separate cleav
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::02f99bceed5755a099ec01e7090fb18d
https://pubmed.ncbi.nlm.nih.gov/1771616
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9
Clustering of fungal allergen-specific IgE antibody responses in allergic subjects
Autor: P C, Potter, J, Juritz, F, Little, M, McCaldin, E B, Dowdle
Publikováno v: Annals of allergy. 66(2)
Statistical analysis of specific IgE immune responses to a panel of nine allergens from 2,094 patients demonstrated significant clustering between Aspergillus fumigatus, Alternaria alternata, and Cladosporium herbarum, not explained by crossreactive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::731d855737e411a11c124ab00fbcf24a
https://pubmed.ncbi.nlm.nih.gov/1994786
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