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pro vyhledávání: '"E B, Conemans"'
Autor:
Bas Havekes, Carolina R. C. Pieterman, E B Conemans, Lodewijk A.A. Brosens, Menno R. Vriens, Cathy B. Moelans, P. H. Bisschop, Lutske Lodewijk, Madeleine L. Drent, I. H. M. Borel Rinkes, H. Th. Marc Timmers, Ad R. M. M. Hermus, A. N. A. van der Horst-Schrivers, Gerlof D. Valk, Folkert H.M. Morsink, Koen M.A. Dreijerink, G. J. A. Offerhaus, W. W. de Herder, Olaf M. Dekkers
Publikováno v:
Conemans, E B, Lodewijk, L, Moelans, C B, Offerhaus, G J A, Pieterman, C R C, Morsink, F H, Dekkers, O M, De Herder, W W, Hermus, A R, Van Der Horst-Schrivers, A N, Drent, M L, Bisschop, P H, Havekes, B, Brosens, L A A, Dreijerink, K M A, Rinkes, I H M B, Timmers, H T M, Valk, G D & Vriens, M R 2018, ' DNA methylation profiling in MEN1-related pancreatic neuroendocrine tumors reveals a potential epigenetic target for treatment ', European Journal of Endocrinology, vol. 179, no. 3, pp. 153-160 . https://doi.org/10.1530/EJE-18-0195
European journal of endocrinology / European Federation of Endocrine Societies, 179(3), 153-160. BioScientifica Ltd.
European Journal of Endocrinology, 179(3), 153-160. BIOSCIENTIFICA LTD
European Journal of Endocrinology, 179, 153-160
European Journal of Endocrinology, 179(3), 153-160
European Journal of Endocrinology, 179, 3, pp. 153-160
European Journal of Endocrinology, 179(3), 153-160. Bioscientifica Ltd
European Journal of Endocrinology, 179(3), 153-160. BioScientifica Ltd.
European Journal of Endocrinology, 179(3), 153. BioScientifica Ltd.
Conemans, E B, Lodewijk, L, Moelans, C B, Offerhaus, G J A, Pieterman, C R C, Morsink, F H, Dekkers, O M, de Herder, W W, Hermus, A R, van der Horst-Schrivers, A N, Drent, M L, Bisschop, P H, Havekes, B, Brosens, L A A, Dreijerink, K M A, Borel Rinkes, I H M, Timmers, H T M, Valk, G D & Vriens, M R 2018, ' DNA methylation profiling in MEN1-related pancreatic neuroendocrine tumors reveals a potential epigenetic target for treatment ', European Journal of Endocrinology, vol. 179, no. 3, pp. 153-160 . https://doi.org/10.1530/EJE-18-0195
European journal of endocrinology / European Federation of Endocrine Societies, 179(3), 153-160. BioScientifica Ltd.
European Journal of Endocrinology, 179(3), 153-160. BIOSCIENTIFICA LTD
European Journal of Endocrinology, 179, 153-160
European Journal of Endocrinology, 179(3), 153-160
European Journal of Endocrinology, 179, 3, pp. 153-160
European Journal of Endocrinology, 179(3), 153-160. Bioscientifica Ltd
European Journal of Endocrinology, 179(3), 153-160. BioScientifica Ltd.
European Journal of Endocrinology, 179(3), 153. BioScientifica Ltd.
Conemans, E B, Lodewijk, L, Moelans, C B, Offerhaus, G J A, Pieterman, C R C, Morsink, F H, Dekkers, O M, de Herder, W W, Hermus, A R, van der Horst-Schrivers, A N, Drent, M L, Bisschop, P H, Havekes, B, Brosens, L A A, Dreijerink, K M A, Borel Rinkes, I H M, Timmers, H T M, Valk, G D & Vriens, M R 2018, ' DNA methylation profiling in MEN1-related pancreatic neuroendocrine tumors reveals a potential epigenetic target for treatment ', European Journal of Endocrinology, vol. 179, no. 3, pp. 153-160 . https://doi.org/10.1530/EJE-18-0195
ObjectiveEpigenetic changes contribute to pancreatic neuroendocrine tumor (PanNET) development. Hypermethylation of promoter DNA as a cause of tumor suppressor gene silencing is a well-established oncogenic mechanism that is potentially reversible an
Autor:
E B, Conemans, G M, Raicu-Ionita, C R C, Pieterman, K M A, Dreijerink, O M, Dekkers, A R, Hermus, W W, de Herder, M L, Drent, A N A, van der Horst-Schrivers, B, Havekes, P H, Bisschop, G J, Offerhaus, I H M, Borel Rinkes, G D, Valk, H Th M, Timmers, M R, Vriens
Publikováno v:
Journal of endocrinological investigation. 41(6)
Pancreatic neuroendocrine tumors are a major manifestation of multiple endocrine neoplasia type 1 (MEN1). This tumor syndrome is caused by germline mutations in MEN1, encoding menin. Insight into pathogenesis of these tumors might lead to new biomark