Zobrazeno 1 - 10
of 51
pro vyhledávání: '"E Alan, Salter"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
PP2A-serine/threonine protein phosphatases function as heterotrimeric holoenzymes, composed of a common scaffold (A-subunit encoded by PPP2R1A/PPP2R1B), a common catalytic (C-subunit encoded by PPP2CA/PPP2CB), and one of many variable regulatory (B)
Externí odkaz:
https://doaj.org/article/f87e56358e52429f84bef8f384e537e2
Autor:
Jianfeng Li, Silvia Garavaglia, Zhaofeng Ye, Andrea Moretti, Olga V. Belyaeva, Alison Beiser, Md Ibrahim, Anna Wilk, Steve McClellan, Alla V. Klyuyeva, Kelli R. Goggans, Natalia Y. Kedishvili, E. Alan Salter, Andrzej Wierzbicki, Marie E. Migaud, Steven J. Mullett, Nathan A. Yates, Carlos J. Camacho, Menico Rizzi, Robert W. Sobol
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Using in silico modeling, Li et al. identify a selective inhibitor for aldehyde dehydrogenase isoform ALDH1A3, which is highly expressed in mesenchymal glioma stem cells and therefore a potential drug target. They solve the structure of the ALDH1A3/M
Externí odkaz:
https://doaj.org/article/d4ab4bd6ea5d4fe5ac3e294cb177d517
Autor:
James H. Davis, Benjamin Siu, Kevin N. West, Andrzej Wierzbicki, Mohammad Soltani, Brooks D. Rabideau, E. Alan Salter, Rome A. Parker
Publikováno v:
Physical Chemistry Chemical Physics. 22:12301-12311
In previous work with thermally robust salts [Cassity et al., Phys. Chem. Chem. Phys., 2017, 19, 31560] it was noted that an increase in the dipole moment of the cation generally led to a decrease in the melting point. Molecular dynamics simulations
Autor:
Andrzej Wierzbicki, Richard A. O'Brien, T. Grant Glover, Edward R. Duranty, Alexandra C. Stenson, E. Alan Salter, Mohammad Soltani, James H. Davis, Jimmie L. McGeehee
Publikováno v:
RSC Advances. 10:20521-20528
Recent work by Wasserscheid, et al. suggests that PPh4+ is an organic molecular ion of truly exceptional thermal stability. Herein we provide data that cements that conclusion: specifically, we show that aliphatic moieties of modified PPh4+-based cat
Autor:
Andrzej Wierzbicki, Mohammad Soltani, Sharhzad Badri, Matthias Zeller, Julian Henseler, James H. Davis, Alexandra C. Stenson, E. Alan Salter, Brandon L. Mash
Publikováno v:
Chemical Communications. 55:13546-13549
Drugs containing amine groups react with CO2 to form crystalline ammonium carbamates or carbamic acids. In this approach, both the cation and anion of the salt, or the neutral CO2 adduct, are derived from the parent drug, generating new crystalline v
Publikováno v:
Catalysts
Volume 10
Issue 6
Catalysts, Vol 10, Iss 674, p 674 (2020)
Volume 10
Issue 6
Catalysts, Vol 10, Iss 674, p 674 (2020)
Serine/threonine protein phosphatase-5 (PP5
PPP5C) is a member of the phosphoprotein phosphatase (PPP) gene family. The PPP catalytic domains feature a bimetal system (M1/M2), an associated bridge hydroxide (W1(OH&minus
)), an M1-bound wate
PPP5C) is a member of the phosphoprotein phosphatase (PPP) gene family. The PPP catalytic domains feature a bimetal system (M1/M2), an associated bridge hydroxide (W1(OH&minus
)), an M1-bound wate
Autor:
Mohammad, Soltani, Jimmie L, McGeehee, Alexandra C, Stenson, Richard A, O'Brien, Edward R, Duranty, E Alan, Salter, Andrzej, Wierzbicki, T Grant, Glover, James H, Davis
Publikováno v:
RSC advances. 10(35)
Recent work by Wasserscheid
Autor:
James H. Davis, Benjamin Siu, Andrzej Wierzbicki, Mohammad Soltani, E. Alan Salter, Kevin N. West
Publikováno v:
Tetrahedron Letters. 58:4628-4631
Seven new ionic liquids have been prepared which contain tetraarylphosphonium cations in which one of the aromatic groups is a quinoline ring. These compounds, which differ from each other in the point of attachment of the quinoline to the phosphorou
Publikováno v:
Cancer Research. 77:221-226
About a third of all human cancers harbor mutations in one of the K-, N-, or HRAS genes that encode an abnormal RAS protein locked in a constitutively activated state to drive malignant transformation and tumor growth. Despite more than three decades
Autor:
Matt Vo, Cody A. Cassity, Mohammad Soltani, Alexandra C. Stenson, Andrzej Wierzbicki, E. Alan Salter, Jimmy L. McGeehee, Katie J. Strickland, Brooks D. Rabideau, James H. Davis, Kevin N. West, Benjamin Siu
Publikováno v:
Physical Chemistry Chemical Physics. 19:31560-31571
A family of mesothermal ionic liquids comprised of tetraarylphosphonium cations and the bis(trifluoromethanesulfonyl)amidate anion are shown to be materials of exceptional thermal stability, enduring (without decomposition) heating in air at 300 °C