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Publikováno v:
Problems of Endocrinology. 66:39-49
Cushing’s disease (CD) is a multisystem disorder of a cortisol excess caused by ACTH -secreting pituitary tumor (corticotropinoma). CD in children is due to somatic or germline mutations with the late onset causing multiple endocrine tumors. If not
Autor:
E. A. Yanar, N. V. Makazan, M. A. Kareva, A. V. Vorontsov, V. P. Vladimirova, O. B. Bezlepkina, V. A. Peterkova
Publikováno v:
Problemy endokrinologii. 68(3)
BACKGROUND: Cushing’s disease (CD) is a rare disorder of a persistent cortisol excess caused by ACTH-secreting pituitary tumor (corticotropinoma). Transsphenoidal surgery (TSS) is a treatment of choice for СD, which effectiveness range is from 70