Zobrazeno 1 - 10
of 178
pro vyhledávání: '"E A Hobbs"'
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191313 (2018)
Saturated fatty acids, such as palmitate, are elevated in metabolically dysfunctional conditions like type 2 diabetes mellitus. Palmitate has been shown to impair insulin sensitivity and suppress protein synthesis while upregulating proteolytic syste
Externí odkaz:
https://doaj.org/article/15d5d45e0b944ca498e7d0234473e6a3
Carbohydrate Active enZymes (CAZymes) are pivotal in biological processes including energy metabolism, cell structure maintenance, signalling and pathogen recognition. Bioinformatic prediction and mining of CAZymes improves our understanding of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbf242f41429441ea8c53b605b718634
https://doi.org/10.1101/2022.12.02.518825
https://doi.org/10.1101/2022.12.02.518825
Autor:
Myra E. Woodworth‐Hobbs, Ben D. Perry, Jill A. Rahnert, Matthew B. Hudson, Bin Zheng, S. Russ Price
Publikováno v:
Physiological Reports, Vol 5, Iss 23, Pp n/a-n/a (2017)
Abstract Lipid accumulation in skeletal muscle results in dysregulation of protein metabolism and muscle atrophy. We previously reported that treating C2C12 myotubes with palmitate (PA), a saturated fatty acid, increases the overall rate of proteolys
Externí odkaz:
https://doaj.org/article/ae841e9c8b8840f1a2de757bd935bbd1
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159181 (2016)
Muscle wasting associated with chronic diseases has been linked to decreased expression of PGC-1α and overexpression of PGC-1α counters muscle loss. CREB, in conjunction with the CREB-regulated transcription coactivator (CRTC2), is a positive modul
Externí odkaz:
https://doaj.org/article/f4a6e9bc6a514aaeb5a1a5a48d1c79a6
Publikováno v:
Journal of Hospital Medicine. 15:599-605
BACKGROUND: Although ensuring high-quality care requires assessment of individual hospitalist performance, current assessment approaches lack consistency and coherence. The Institute of Medicine’s STEEEP framework for quality healthcare conceptuali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43b16555d2b260c444224eeaab0aaca
https://doi.org/10.12788/jhm.3445
https://doi.org/10.12788/jhm.3445
Autor:
Kimberly Pedram, Nargiza Kurbanova, Carolyn Marcelo, Michelle Brooks, Alice Wong, Laura E Paletta-Hobbs, Adam M. Garber, Rehan Qayyum
Publikováno v:
Cureus
Background Medical training relies on direct observations and formative feedback. After residency graduation, opportunities to receive feedback on clinical teaching diminish. Although feedback through learner evaluations is common, these evaluations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c308ee7bce8fdb9c323ef8066754a604
https://doi.org/10.7759/cureus.7076
https://doi.org/10.7759/cureus.7076
Publikováno v:
Kidney Research and Clinical Practice, Vol 31, Iss 2, p A92 (2012)
Muscle atrophy is prevalent in chronic kidney disease (CKD) patients. MicroRNAs play a critical role in biological processes including muscle atrophy. MicroRNA-23a (miR-23a) negatively regulates the expression of two atrophy-related ubiquitin ligases
Externí odkaz:
https://doaj.org/article/a39ad03fb616440780d7c0ac76fe49cd
Publikováno v:
Kidney Research and Clinical Practice, Vol 31, Iss 2, p A92 (2012)
Hypertriglyceridemia is a comorbidity of chronic kidney disease (CKD) that contributes to insulin resistance and dysfunctional protein metabolism in skeletal muscle, resulting in debilitating muscle atrophy. The saturated fatty acid palmitate (PA) in
Externí odkaz:
https://doaj.org/article/faaebec937a34423b3d634f4bd85fbdd
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191313 (2018)
PLoS ONE
PLoS ONE
Saturated fatty acids, such as palmitate, are elevated in metabolically dysfunctional conditions like type 2 diabetes mellitus. Palmitate has been shown to impair insulin sensitivity and suppress protein synthesis while upregulating proteolytic syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57903ece4d99ed1f53c8f692fcaf07e1
http://europepmc.org/articles/PMC5766250?pdf=render
http://europepmc.org/articles/PMC5766250?pdf=render
Autor:
Matthew B. Hudson, Myra E. Woodworth-Hobbs, Harold A. Franch, Jill A. Rahnert, Bin Zheng, S. Russ Price
Publikováno v:
American Journal of Physiology-Cell Physiology. 307:C314-C319
Skeletal muscle atrophy occurs in response to a variety of conditions including chronic kidney disease, diabetes, cancer, and elevated glucocorticoids. MicroRNAs (miR) may play a role in the wasting process. Activation of the forkhead box O3 (FoxO3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd95b1dfb3cb5675cbd89a172c3ab02
https://doi.org/10.1152/ajpcell.00395.2013
https://doi.org/10.1152/ajpcell.00395.2013