Výsledky vyhledávání - "E A, Tonevitsky"

Hypoxia enhances transcytosis in intestinal enterocytes

Autor: AA Kurnosov, AI Osipyants, DV Maltseva, E. A. Tonevitsky, Sergey Nikulin, M. P. Raigorodskaya, M. Y. Shkurnikov, Stepan Nersisyan

Publikováno v: MicroRNA in ocular pathology. :60-66

The integrity of the intestinal epithelial cell lining is crucial for the normal intestinal function. As a rule, intestinal inflammation is associated with additional tissue hypoxia, leading to the loss of epithelial monolayer integrity. However, in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6024a6e3e855df68da2a7e38b5e6d7b6
https://doi.org/10.24075/brsmu.2020.049

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Loop-mediated isothermal amplification holds great potential for massive COVID-19 diagnostics

Autor: A. I. Osipyants, V. I. Vechorko, K. A. Fomicheva, J. A. Makarova, A. A. Pokryschenko, M. Y. Shkurnikov, E. A. Tonevitsky

Publikováno v: Biotekhnologiya. 36:6-12

Real-time RT-PCR currently remains most popular for early COVID-19 diagnostics. However Loop-mediated isothermal amplification (LAMP) method outperform real-time RT-PCR in rapidity and simplicity because it doesn't require expensive laboratory equipm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e519c96e1727de7011cc65884bf44e4
https://doi.org/10.21519/0234-2758-2020-36-5-6-12

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Expression of CD44 Isoforms in Tumor Samples and Cell Lines of Human Colorectal Cancer

Autor: V O, Novosad, I S, Polikanova, E A, Tonevitsky, D V, Maltseva

Publikováno v: Bulletin of experimental biology and medicine. 173(1)

Detection of colorectal cancer biomarkers (CRC) remains an urgent task for the diagnosis and prediction of the disease course. A promising approach is the study of cancer stem cell markers. The cell surface glycoprotein CD44 is very important for CRC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a46e1562eae22c30c101291048f7673
https://pubmed.ncbi.nlm.nih.gov/35618971

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Changes in the Expression of miRNA Isoforms and Their Targets in HT-29 Cells after Hypoxic Exposure

Autor: M P, Raigorodskaya, A P, Zhiyanov, D A, Averinskaya, E A, Tonevitsky

Publikováno v: Bulletin of experimental biology and medicine. 173(1)

Tumor hypoxia is one of the main causes of progression and metastasis of colorectal cancer. Changes in the expression of miRNA responsible for post-translation regulation of gene expression is an important molecular mechanism of cell response to hypo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c4252956f37cbbdb90217635fb81380
https://pubmed.ncbi.nlm.nih.gov/35624351

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Intracellular Transport of Ribosome-Inactivating Proteins Depends on Annexin 13

Autor: D. V. Maltseva, E A Tonevitsky, Victor G. Zgoda, M P Raigorodskaya, E N Knyazev

Publikováno v: Doklady Biochemistry and Biophysics. 494:219-221

In the present study, we assessed the role of annexin 13 membrane-binding protein (ANXA13) in the intracellular transport of vesicles containing type II ribosome-inactivating proteins (RIP-IIs). A modified human intestinal epithelial cell line HT29 w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff6c5150edc6b5cc1e1468a8bdb5932
https://doi.org/10.1134/s1607672920040092

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Relationship between the Expression Level of PSMD11 and Other Proteasome Proteins with the Activity of Ricin and Viscumin

Autor: M P Raigorodskaya, D. V. Maltseva, O. V. Tikhonova, E N Knyazev, E A Tonevitsky

Publikováno v: Doklady Biochemistry and Biophysics. 493:198-200

The role of proteasome proteins and proteins of the ERAD system in the cytotoxicity of type II ribosome-inactivating proteins ricin and viscumin was investigated. For this, the cell line of colorectal adenocarcinoma HT29, as well as the HT29-sh002 li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5d70c58adc9d9d3aeb223d9dbc1339
https://doi.org/10.1134/s1607672920040080

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Epithelial to Mesenchymal Transition Marker in 2D and 3D Colon Cancer Cell Cultures in the Presence of Laminin 332 and 411

Autor: J. A. Makarova, E A Tonevitsky, S A Rodin, I M Tsypina, A. Yu. Khristichenko, D. V. Maltseva

Publikováno v: Molecular Biology. 53:291-298

Received August 28, 2018; revised October 10, 2018; accepted November 6, 2018 The loss of apical-basal cell polarity is a necessary stage of the epithelial-mesenchymal transition (EMT). Polarized epithelial cells interact with the basement membrane (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7f511758aa16548b092b4eb11b97ee0
https://doi.org/10.1134/s0026893319020110

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Effect of ketoconazole on the transport and metabolism of drugs in the human liver cell model

Autor: E. A. Tonevitsky, Andrey A. Poloznikov, Sergey Nikulin

Publikováno v: Russian Chemical Bulletin. 66:150-155

The effect of ketoconazole on the biotransformation of amiodarone, rosiglitazone, and cyclophosphamide was studied using the human liver cell model based on differentiated HepaRG spheroids. The concentrations of major metabolites of amiodarone and cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a52c83231a299bb3ad554e5f8d8db5d8
https://doi.org/10.1007/s11172-017-1713-z

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