Zobrazeno 1 - 4
of 4
pro vyhledávání: '"E A, Sudbeck"'
Autor:
Xing-Ping Liu, Sutapa Ghosh, E. A. Sudbeck, C Mao, R. K. Narla, Fatih M. Uckun, C. S. Navara, A. O. Vassilev
Publikováno v:
Current Cancer Drug Targets. 1:59-71
Recently identified agents that interact with cytoskeletal elements such as tubulin include synthetic spiroketal pyrans (SPIKET) and monotetrahydrofuran compounds (COBRA compounds). SPIKET compounds target the spongistatin binding site of beta-tubuli
Autor:
E A, Sudbeck, F M, Uckun
Publikováno v:
IDrugs : the investigational drugs journal. 2(10)
The Janus family of tyrosine kinases (JAKs) has emerged as a promising target for therapeutic agents. JAKs are involved in pathways which help regulate cellular functions in the lympho-hematopoietic system critical for cell proliferation and cell sur
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 166
Autor:
E A, Sudbeck, M J, Jedrzejas, S, Singh, W J, Brouillette, G M, Air, W G, Laver, Y S, Babu, S, Bantia, P, Chand, N, Chu, J A, Montgomery, D A, Walsh, M, Luo
Publikováno v:
Journal of molecular biology. 267(3)
The active site of influenza virus neuraminidase (NA) is formed by 11 universally conserved residues. A guanidino group incorporated into two unrelated NA inhibitors was previously reported to occupy different negatively charged sites in the NA activ