Zobrazeno 1 - 10
of 27
pro vyhledávání: '"E A, Straaten"'
Autor:
Charlotte F.J. Van Tuijn, Mitchel E. van Straaten, Erfan Nur, Bart J. Biemond, Jarom Heijmans
Publikováno v:
Blood. 140:11135-11136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e25a6b29af2b0c0c26bbe825fdc7329e
https://doi.org/10.1182/blood-2022-166551
https://doi.org/10.1182/blood-2022-166551
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85735 (2014)
Deletion or repression of Aspergillus nidulans ugmA (AnugmA), involved in galactofuranose biosynthesis, impairs growth and increases sensitivity to Caspofungin, a β-1,3-glucan synthesis antagonist. The A. fumigatus UgmA (AfUgmA) crystal structure ha
Externí odkaz:
https://doaj.org/article/092ab9391e294d87a7d07a3db932d2e2
Autor:
B. Mario Pinto, Karin E. van Straaten, Cinzia Colombo, Sankar Mohan, Yun Shi, Jijin R. A. Kuttiyatveetil, David A. R. Sanders, Nataliya Zalatar
Publikováno v:
ChemBioChem. 17:2264-2273
UDP-galactopyranose mutase (UGM), a key enzyme in the biosynthesis of mycobacterial cell walls, is a potential target for the treatment of tuberculosis. In this work, we investigate binding models of a non-substrate-like inhibitor, MS-208, with M. tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99895bfc25e883e032f180d7e074c8c
https://doi.org/10.1002/cbic.201600469
https://doi.org/10.1002/cbic.201600469
Autor:
Hongyan Zheng, Shazia Anjum, David A. R. Sanders, Egiroh Omene, Karin E. van Straaten, David R. J. Palmer, Julie Boisvert-Martel, Rajendra C. Jagdhane, Ed S. Krol, Natasha D. Vetter, David M. Langill, Isaac Asiamah
Publikováno v:
Journal of the American Chemical Society. 135:5970-5973
The ntd operon in Bacillus subtilis is essential for biosynthesis of 3,3'-neotrehalosadiamine (NTD), an unusual nonreducing disaccharide reported to have antibiotic properties. It has been proposed that the three enzymes encoded within this operon, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe3474ca9c8b82c37d148646ee37c32
https://doi.org/10.1021/ja4010255
https://doi.org/10.1021/ja4010255
Autor:
Roger A. Pierson, Gregg P. Adams, Karin E. van Straaten, Louis T. J. Delbaere, Marcelo H Ratto, Ximena Valderrama, Y.A. Leduc
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
A component in seminal fluid elicits an ovulatory response and has been discovered in every species examined thus far. The existence of an ovulation-inducing factor (OIF) in seminal plasma has broad implications and evokes questions about identity, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d458c38d25febdef7c7f88022a69a1
https://doi.org/10.1073/pnas.1206273109
https://doi.org/10.1073/pnas.1206273109
Publikováno v:
The Journal of Biological Chemistry
Background: UDP-galactopyranose mutase (UGM) is a critical enzyme for the proper formation of the cell wall of pathogenic microbes. Results: The structure of UGM in complex with substrate reveals novel features of substrate binding. Conclusion: Oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826071d006fbddb79e0e199fe66db1ee
http://europepmc.org/articles/PMC3322874
http://europepmc.org/articles/PMC3322874
Publikováno v:
Journal of Molecular Biology. 394:864-877
d -Galactofuranose (Galf) residues are found in the cell walls of pathogenic microbes such as Mycobacterium tuberculosis, and are essential for viability. UDP-galactopyranose mutase (UGM) is a unique flavo-enzyme that catalyzes the reversible convers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ece96614de648af3f4e54d306447587
https://doi.org/10.1016/j.jmb.2009.10.013
https://doi.org/10.1016/j.jmb.2009.10.013
Autor:
Alexei Savchenko, David A. R. Sanders, Ricardo Valladares, Xiaohui Xu, Claudio F. Gonzalez, Karin E. van Straaten
Publikováno v:
Protein Science. 18:2196-2202
The structure of the Atu1476 protein from Agrobacterium tumefaciens was determined at 2 A resolution. The crystal structure and biochemical characterization of this enzyme support the conclusion that this protein is an S-formylglutathione hydrolase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2582060301b2bd50c47f5cc484559a2b
https://doi.org/10.1002/pro.216
https://doi.org/10.1002/pro.216
Publikováno v:
Journal of Biological Chemistry. 282:21197-21205
Crystal structures of an inactive mutant (D308A) of the lytic transglycosylase MltA from Escherichia coli have been determined in two different apo-forms, as well as in complex with the substrate analogue chitohexaose. The chitohexaose binds with all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e9c68862162607a181dc7422132b06c
https://doi.org/10.1074/jbc.m701818200
https://doi.org/10.1074/jbc.m701818200
Autor:
Karin E. van Straaten, Miroslaw Cygler, Lei Li, Michal T. Boniecki, Ksenia Beyrakhova, Deborah H. Anderson
Publikováno v:
The Journal of biological chemistry. 291(30)
Legionella pneumophila is a causative agent of a severe pneumonia, known as Legionnaires' disease. Legionella pathogenicity is mediated by specific virulence factors, called bacterial effectors, which are injected into the invaded host cell by the ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24a02d92a19fccf1cbc234adc88b9b4
https://pubmed.ncbi.nlm.nih.gov/27226543
https://pubmed.ncbi.nlm.nih.gov/27226543