Zobrazeno 1 - 10 of 14 pro vyhledávání: '"E A, Shirinian"'
1
[Effect of a postsynaptic alpha2-adrenoreceptor antagonist beditin on the rat resistance to seizure and Ca(+)-level in the brain tissue]
Autor: E A, Shirinian, S A, Arutiunian, A A, Petrosian, G A, Gevorkian, E A, Markarian, S O, Vartanian, O S, Medvedev, B T, Garibdzhanian
Publikováno v: Eksperimental'naia i klinicheskaia farmakologiia. 67(1)
In rats with a hemodynamic disorder caused by acute myocardial ischemia, preliminary administration of beditin in a dose of 25 mg/kg fully prevents a manifold increase in the level of 45Ca2+ in the cytosol of brain cells and leads to enhanced trappin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f38b45e890f469444e6d91e9c4fd6673
https://pubmed.ncbi.nlm.nih.gov/15079900
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2
[Effect of beditine on the cerebral circulation and various metabolic parameters]
Autor: S A, Mirzoian, A A, Petrosian, S A, Arutiunian, T G, Gukasian, O S, Medvedev, E A, Shirinian
Publikováno v: Eksperimental'naia i klinicheskaia farmakologiia. 63(4)
Beditin, or 2-(2-amino-4-thiazolyl)-1,4-benzodioxane hydrochloride, is a new benzodioxane derivative possessing antihypoxant and alpha 2-adrenoreceptor blocker properties. In contrast to idazoxan, a well-known alpha 2-adrenoreceptor blocker, beditin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afc3f91e775ae7a1a7d944a211870266
https://pubmed.ncbi.nlm.nih.gov/11022300
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3
[Various aspects of increased resistance of the brain tissue and its vessels to extreme effects with the use of GABAergic compounds and Ca(2+) antagonists]
Autor: V P, Akopian, K V, Melkonian, V M, Samvelian, E A, Shirinian, N R, Mirzoian
Publikováno v: Eksperimental'naia i klinicheskaia farmakologiia. 60(5)
Experiments on rats showed that the morpho-functional state of the cerebral cortex microcirculatory bed suffers marked changes in different periods of hypokinesia. This was accompanied with obvious morphological changes in the brain, the development
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b6d2a664d4518502c3434c40dd78cdf1
https://pubmed.ncbi.nlm.nih.gov/9483402
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4
[The effect of verapamil on changes in the Ca2+ content of the intracellular structures of organs during acute myocardial ischemia]
Autor: E G, Dzhanpoladian, V M, Samvelian, S A, Arutiunian, E A, Shirinian
Publikováno v: Eksperimental'naia i klinicheskaia farmakologiia. 59(5)
In experiments on rats with acute myocardial infarction induced by occlusion of the left coronary artery in conscious animals the protective effect of verapamil on the heart, brain, liver, and kidneys in this disease was studied. The effectiveness of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ab48947ebe231172fd7a11e93989ee4
https://pubmed.ncbi.nlm.nih.gov/9026202
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5
[The participation of the hypophyseal-adrenal system in regulating alpha 2-adrenoreceptor reactivity. The effects of extreme exposures and alpha 2-adrenoblockaders]
Autor: E A, Shirinian, O M, Martirosian, S A, Arutiunian, T K, Ataian
Publikováno v: Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. 76(9)
The simulation of the hypo- and hyperactivity of the hypophysis-adrenocortical system induced considerable changes in the reactivity of alpha 2-adrenoceptors, as well as in the resistance of the organism to stressful influences. The findings support
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4ee100c2d78a17745a46a7cfc4c3573
https://pubmed.ncbi.nlm.nih.gov/1981756
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7
[New model of dynamic work in small laboratory animalsu]
Autor: O M, Avakian, E A, Shirinian
Publikováno v: Biulleten' eksperimental'noi biologii i meditsiny. 84(9)
A new method of compelling rats and mice to perform uninterrupted dynamic work has been devised. The animal, fixed from its tail and situated in vertical position in respect to the surface of the water with which it comes in contact only with its muz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9e38e9a81fa4cb4614fb1bee08caa5d2
https://pubmed.ncbi.nlm.nih.gov/912096
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10
[Effect of adrenalectomy and chemical sympathectomy on the catecholamines content in the central nervous system in hemorrhagic stress]
Autor: E A, Shirinian, O M, Avakian
Publikováno v: Voprosy meditsinskoi khimii. 24(2)
Content of adrenaline, noradrenaline, dopamine and normetanephrine was estimated by means of trihydroxyindole method in samples of brain and its hypothalamic part from intact, adrenal- and sympathectomized rats within 15 min, 24 and 72 hrs after hemo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::303e9a4f87aae06cf46ba508c165e819
https://pubmed.ncbi.nlm.nih.gov/664447
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