Zobrazeno 1 - 10
of 11
pro vyhledávání: '"E A, Reap"'
Publikováno v:
The Journal of Immunology. 156:812-817
The MHC exerts an important influence on systemic autoimmune disease. In C57BL/6-lpr/lpr (B6/lpr) mice, substitution of the H-2d instead of the H-2b MHC haplotype results in a global reduction in autoantibody levels. Since H-2d expresses both I-A and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8957d7e25b763156c9af1410681e4b7d
https://doi.org/10.4049/jimmunol.156.2.812
https://doi.org/10.4049/jimmunol.156.2.812
Publikováno v:
The Journal of Immunology. 155:5455-5462
The lpr gene encodes a defective form of the fas gene that mediates apoptosis, and its expression results in autoantibodies and massive lymphadenopathy. bcl-2, another gene locus that affects programmed cell death, acts to inhibit apoptosis. Since mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca8b454234c271a9d7093dde39dc26fd
https://doi.org/10.4049/jimmunol.155.11.5455
https://doi.org/10.4049/jimmunol.155.11.5455
Publikováno v:
The Journal of Immunology. 154:936-943
The murine gene lpr encodes an aberrant form of the apoptosis-inducing receptor Fas. The gene gld, which causes an autoimmune syndrome phenotypically identical to that caused by lpr, encodes a mutant Fas ligand. Because the lpr gene must be expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3660d16e5567cf8c65544a2713a7173
https://doi.org/10.4049/jimmunol.154.2.936
https://doi.org/10.4049/jimmunol.154.2.936
Publikováno v:
The Journal of Immunology. 151:7316-7323
B1 (CD5+) B cells have been implicated as a source of certain autoantibodies in several murine and human studies. We have previously shown in the lpr model of autoimmunity, however, that conventional B cells, not B1 cells, were the source of autoanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4215f735b72ee96224c702b9099bf399
https://doi.org/10.4049/jimmunol.151.12.7316
https://doi.org/10.4049/jimmunol.151.12.7316
Publikováno v:
Current topics in microbiology and immunology. 252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4b223fecd2364ccdd8764f202095656
https://pubmed.ncbi.nlm.nih.gov/11125477
https://pubmed.ncbi.nlm.nih.gov/11125477
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(9)
Fas (CD95) is a cell surface protein that mediates apoptosis. lpr is a mutation of the Fas gene caused by a retroviral insertion resulting in premature termination of transcription and aberrant splicing of Fas mRNA. Mice homozygous for the lpr gene d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa373a906b0d6c8399746166372bb3a0
https://pubmed.ncbi.nlm.nih.gov/9794379
https://pubmed.ncbi.nlm.nih.gov/9794379
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(1)
We wondered whether the apoptosis known to occur after UV-B irradiation might involve the Fas/Fas ligand (FasL) signaling pathway. We exposed PBLs from normal individuals, and also the Jurkat (E6-1) and U937 cell lines, to graded doses of UV-B irradi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dec6054f63a67a027e3ba4d634dc6526
https://pubmed.ncbi.nlm.nih.gov/9647230
https://pubmed.ncbi.nlm.nih.gov/9647230
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(3)
lpr, a murine mutation of the Fas apoptosis receptor, causes lymphadenopathy and autoantibody production, with lymphadenopathy primarily due to a population of CD4-CD8-B220+ T cells. Previous in vivo experiments, in which lpr and normal bone marrow c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42b8f3ae82a9ec7b6aa75575e4e8352c
https://pubmed.ncbi.nlm.nih.gov/9570572
https://pubmed.ncbi.nlm.nih.gov/9570572
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(11)
The lpr gene encodes a defective form of the fas gene that mediates apoptosis, and its expression results in autoantibodies and massive lymphadenopathy. bcl-2, another gene locus that affects programmed cell death, acts to inhibit apoptosis. Since mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f0160bfaa2fabc13f279d8369f54b31
https://pubmed.ncbi.nlm.nih.gov/7594564
https://pubmed.ncbi.nlm.nih.gov/7594564
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(2)
The murine gene lpr encodes an aberrant form of the apoptosis-inducing receptor Fas. The gene gld, which causes an autoimmune syndrome phenotypically identical to that caused by lpr, encodes a mutant Fas ligand. Because the lpr gene must be expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94bd6507c8a65a5f2a5228b62c910587
https://pubmed.ncbi.nlm.nih.gov/7529292
https://pubmed.ncbi.nlm.nih.gov/7529292