Zobrazeno 1 - 10
of 35
pro vyhledávání: '"E A, Padlan"'
Publikováno v:
The Journal of Immunology. 153:1161-1170
We are studying murine mAbs against two carbohydrate epitopes, 3-fucosyllactosamine (Le(x), CD15) and galactosylgloboside. The VH domains of both panels of Ab are encoded by VH441, a member of the X24 family of Ig genes. To evaluate the contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::702083e9de8d89e6d711af2917c18b9e
https://doi.org/10.4049/jimmunol.153.3.1161
https://doi.org/10.4049/jimmunol.153.3.1161
Publikováno v:
Scopus-Elsevier
The Journal of Experimental Medicine
The Journal of Experimental Medicine
To gain insight into the rules that govern the binding of endogenous and viral peptides to a given major histocompatibility complex (MHC) class I molecule, we characterized the amino acid sequences of a set of self peptides bound by a soluble analogu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195b0719e77d0115f55e22d73bde8b6b
https://doi.org/10.1084/jem.176.6.1681
https://doi.org/10.1084/jem.176.6.1681
Publikováno v:
The Journal of Immunology. 144:2620-2626
The reactivity of 23 mouse monoclonal Ig with a rabbit polyclonal antiserum to VH of anti-alpha(1----6)dextran 19.22.1 and with a monoclonal anti-VH of anti-DNP MOPC315, when correlated with amino acid sequence, identified several residues in the fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7388873c9a0b070290d053b374f395a
https://doi.org/10.4049/jimmunol.144.7.2620
https://doi.org/10.4049/jimmunol.144.7.2620
Generation and characterization of a single gene-encoded single-chain-tetravalent antitumor antibody
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
Monoclonal antibody (mAb) CC49, a murine IgG1, reacts with the tumor-associated glycoprotein-72 expressed on a variety of carcinomas. In clinical trials, radiolabeled CC49 has shown excellent tumor localization to a variety of carcinomas. To minimize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6bc460ef1000de7827383401a3336ee8
https://pubmed.ncbi.nlm.nih.gov/10541352
https://pubmed.ncbi.nlm.nih.gov/10541352
Publikováno v:
Journal of molecular biology. 289(5)
We describe here the structure of a murine T cell receptor (TCR) Valpha2.6Jalpha38 (TCRAV2S6J38) domain, derived from a T cell hybridoma with specificity for the H-2Ddmajor histocompatibility complex class I molecule bound to a decamer peptide, P18-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec248ba299dbc741f89cb8b10958258b
https://pubmed.ncbi.nlm.nih.gov/10373358
https://pubmed.ncbi.nlm.nih.gov/10373358
Publikováno v:
Allergy. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28831472d18611df457ba1000f5a3122
https://pubmed.ncbi.nlm.nih.gov/9788713
https://pubmed.ncbi.nlm.nih.gov/9788713
Autor:
A D, Santos, E A, Padlan
Publikováno v:
Progress in nucleic acid research and molecular biology. 60
Two procedures for improving the efficacy of medically important antibodies are described. The first procedure is designed to reduce the immunogenicity of nonhuman antibodies to the barest minimum--the "humanization" is accomplished by transplanting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c45e32cb89db55f8bd233a94dcab8d6
https://pubmed.ncbi.nlm.nih.gov/9594575
https://pubmed.ncbi.nlm.nih.gov/9594575
Publikováno v:
The Journal of biological chemistry. 271(21)
The three-dimensional structure of the Fab of TR1.9, a high-affinity IgG1, kappa human autoantibody to thyroid peroxidase, was determined crystallographically to a resolution of 2.0 A. The combining site was found to be relatively flat, like other an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3fc17b5d7a6a312604051483fdcb54c
https://pubmed.ncbi.nlm.nih.gov/8647813
https://pubmed.ncbi.nlm.nih.gov/8647813
Publikováno v:
Human antibodies and hybridomas. 7(3)
A murine monoclonal antibody H67 was characterized for the binding specificity, which showed that H67 recognizes a disulfide-bond-dependent conformational epitope of common a antigenic determinant on the hepatitis B surface antigen. The result sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f6b6670f1131d927c02056107567ec7
https://pubmed.ncbi.nlm.nih.gov/9057059
https://pubmed.ncbi.nlm.nih.gov/9057059
Autor:
E A, Padlan
Publikováno v:
Advances in protein chemistry. 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cde6669f60bcd6c1611a352adb050c6
https://pubmed.ncbi.nlm.nih.gov/8908297
https://pubmed.ncbi.nlm.nih.gov/8908297