Skeletal muscle transcriptomics identifies common pathways in nerve crush injury and ageing

Autor: C. A. Staunton, E. D. Owen, K. Hemmings, A. Vasilaki, A. McArdle, R. Barrett-Jolley, M. J. Jackson

Publikováno v: Skeletal Muscle, Vol 12, Iss 1, Pp 1-20 (2022)

Abstract Motor unit remodelling involving repeated denervation and re-innervation occurs throughout life. The efficiency of this process declines with age contributing to neuromuscular deficits. This study investigated differentially expressed genes

Externí odkaz: https://doaj.org/article/2478ca802cc7430292431e40db8b85e4

Deletion ofSod1in Motor Neurons Exacerbates Age-Related Changes in Axons and Neuromuscular Junctions in Mice

Autor: N. Pollock, P. C. Macpherson, C. A. Staunton, K. Hemmings, C. S. Davis, E. D. Owen, A. Vasilaki, H. Van Remmen, A. Richardson, A. McArdle, S. V. Brooks, M. J. Jackson

Publikováno v: eneuro. 10:ENEURO.0086-22.2023

Whole-body knock-out of Cu,Zn superoxide dismutase (Sod1KO) results in accelerated, age-related loss of muscle mass and function associated with neuromuscular junction (NMJ) breakdown similar to sarcopenia. In order to determine whether altered redox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::145cbb2b7f2cc33d112ca59d9ecf2a49
https://doi.org/10.1523/eneuro.0086-22.2023

Mitochondrial molecular genetic results in a South African cohort: divergent mitochondrial and nuclear DNA findings

Autor: E. P. Owen, Surita Meldau, Kashief Khan, Gillian Riordan

Publikováno v: Journal of clinical pathology. 75(1)

AimsMitochondrial diseases form one of the largest groups of inborn errors of metabolism. The birth prevalence is approximately 1/5000 in well-studied populations, but little has been reported from Sub-Saharan Africa. The aim of this study was to des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a893e6d6ca428cacb7eb1e0e45573e6
https://pubmed.ncbi.nlm.nih.gov/33115810

Quantum correlations and limit cycles in the driven-dissipative Heisenberg lattice

Autor: Davide Rossini, Rosario Fazio, Jiasen Jin, E. T. Owen, Michael J. Hartmann

Publikováno v: New journal of physics 20 (2018). doi:10.1088/1367-2630/aab7d3
info:cnr-pdr/source/autori:Owen E.T.; Jin J.; Rossini D.; Fazio R.; Hartmann M.J./titolo:Quantum correlations and limit cycles in the driven-dissipative Heisenberg lattice/doi:10.1088%2F1367-2630%2Faab7d3/rivista:New journal of physics/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:20
New journal of physics, 2018, Vol.20(4), pp.045004 [Peer Reviewed Journal]

Driven-dissipative quantum many-body systems have attracted increasing interest in recent years as they lead to novel classes of quantum many-body phenomena. In particular, mean-field calculations predict limit cycle phases, slow oscillations instead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22cb0c9f03f2792ed9b695125e638234
https://publications.cnr.it/doc/393221

Glutaric aciduria type 1 in South Africa—high incidence of glutaryl-CoA dehydrogenase deficiency in black South Africans

Autor: Ingrid Baumgarten, E. P. Owen, Nicholas D. Watermeyer, Felicity Leisegang, Nigel J. Manning, Howard E. Henderson, George van der Watt, Peter Berman, Surita Meldau, Simon E. Olpin

Publikováno v: Molecular Genetics and Metabolism. 101:178-182

Glutaric Aciduria type 1 (GA 1) is an inherited disorder of lysine and tryptophan catabolism that typically manifests in infants with acute cerebral injury associated with intercurrent illness. We investigated the clinical, biochemical and molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd25c740b28678ac623d63fc401dcdc
https://doi.org/10.1016/j.ymgme.2010.07.018