Výsledky vyhledávání - "E A, Mickler"

Effect of intraarticular hyaluronan injection on synovial fluid hyaluronan in the early stage of canine post-traumatic osteoarthritis

Autor: G N, Smith, E A, Mickler, S L, Myers, K D, Brandt

Publikováno v: The Journal of rheumatology. 28(6)

To determine how the quantity and molecular weight of synovial fluid hyaluronan (HA) within the synovial fluid (SF) of osteoarthritis (OA) joints is affected by intraarticular injection of HA.Dogs in which OA was induced by transection of the anterio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3e24f0b44ade5401125977613f74072e
https://pubmed.ncbi.nlm.nih.gov/11409129

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Specificity of inhibition of matrix metalloproteinase activity by doxycycline: relationship to structure of the enzyme

Autor: G N, Smith, E A, Mickler, K A, Hasty, K D, Brandt

Publikováno v: Arthritis and rheumatism. 42(6)

To investigate the inhibition of matrix metalloproteinase 1 (MMP-1), MMP-8, and MMP-13 by doxycycline, and to determine whether the variable hemopexin-like domain of each MMP was responsible for the differences in susceptibility to doxycycline inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f337a93df4ecded9021997f787af52e3
https://pubmed.ncbi.nlm.nih.gov/10366106

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Diacerhein treatment reduces the severity of osteoarthritis in the canine cruciate-deficiency model of osteoarthritis

Autor: G N, Smith, S L, Myers, K D, Brandt, E A, Mickler, M E, Albrecht

Publikováno v: Arthritis and rheumatism. 42(3)

To determine if diacerhein protects against the early stages of joint damage in a canine model of osteoarthritis (OA).OA was induced in 20 adult mongrel dogs by transection of the anterior cruciate ligament of the left knee. Beginning the day after s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e97c15e81e0e28f469a97445477f5ce8
https://pubmed.ncbi.nlm.nih.gov/10088778

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Effect of intraarticular hyaluronan injection in experimental canine osteoarthritis

Autor: G N, Smith, S L, Myers, K D, Brandt, E A, Mickler

Publikováno v: Arthritis and rheumatism. 41(6)

To determine if intraarticular injections of hyaluronan (HA) protect against the early stages of joint damage in a canine model of osteoarthritis (OA).OA was induced in adult mongrel dogs by transection of the anterior cruciate ligament of the left k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b6543f635ada67212f458a014b4bc91e
https://pubmed.ncbi.nlm.nih.gov/9627007

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Inhibition of recombinant human neutrophil collagenase by doxycycline is pH dependent

Autor: G N, Smith, K D, Brandt, E A, Mickler, K A, Hasty

Publikováno v: The Journal of rheumatology. 24(9)

To examine, as part of an evaluation of the role of matrix metalloproteinase (MMP) inhibition in the amelioration of cartilage damage by doxycycline, the effect of pH on the inhibition of activity and reduction in stability of recombinant human neutr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::55b92079b2ff45b22876e76bb6c0be29
https://pubmed.ncbi.nlm.nih.gov/9292802

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Synthesis of a phenotypically abnormal type XI: type II collagen ratio by chondrocytes from canine osteoarthritic cartilage

Autor: G N, Smith, E A, Mickler, K D, Brandt

Publikováno v: Osteoarthritis and cartilage. 2(3)

Collagen synthesis by osteoarthritic cartilage from dogs that had undergone anterior cruciate ligament transection was measured in short-term organ cultures and chondrocyte suspension cultures. Slices of osteoarthritic cartilage from unstable knees 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8d0de0e65f1e13e9d420db0fe54597a
https://pubmed.ncbi.nlm.nih.gov/11550676

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