Zobrazeno 1 - 10
of 1 080
pro vyhledávání: '"E A, Abel"'
Autor:
Jennifer Streeter, Luis Persaud, Jason Gao, Deeraj Manika, Will Fairman, Luis Miguel García-Peña, Alex Marti, Chethan Manika, Shreya Gaddi, Brandon Schickling, Renata O. Pereira, E. Dale Abel
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionReducing Optic Atrophy 1 (OPA1) expression in skeletal muscle in male mice induces Activation Transcription Factor 4 (ATF4) and the integrated stress response (ISR). Additionally, skeletal muscle secretion of Fibroblast Growth Factor 21 (
Externí odkaz:
https://doaj.org/article/61ebdfd6e8b54436af9c7ebb99618461
Autor:
Amanda Davenport, Chase W. Kessinger, Ryan D. Pfeiffer, Nikita Shah, Richard Xu, E. Dale Abel, Nathan R. Tucker, Zhiqiang Lin
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 9, Iss , Pp 100081- (2024)
We have previously shown that the Myh6 promoter drives Cre expression in a subset of male germ line cells in three independent Myh6-Cre mouse lines, including two transgenic lines and one knock-in allele. In this study, we further compared the tissue
Externí odkaz:
https://doaj.org/article/939b965e49d341b48bd2b18c3a47eca5
Autor:
Sarah H. Bjorkman, Alex Marti, Jayashree Jena, Luis Miguel García-Peña, Eric T. Weatherford, Kevin Kato, Jivan Koneru, Jason Chen, Ayushi Sood, Matthew J. Potthoff, Christopher M. Adams, E. Dale Abel, Renata O. Pereira
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract In brown adipose tissue (BAT), short-term cold exposure induces the activating transcription factor 4 (ATF4), and its downstream target fibroblast growth factor 21 (FGF21). Induction of ATF4 in BAT in response to mitochondrial stress is requ
Externí odkaz:
https://doaj.org/article/438fdd6b7f334f3d84b2767d8e8eb602
Autor:
Natali Froese, Malgorzata Szaroszyk, Paolo Galuppo, Joseph R. Visker, Christopher Werlein, Mortimer Korf‐Klingebiel, Dominik Berliner, Marc R. Reboll, Rana Hamouche, Simona Gegel, Yong Wang, Winfried Hofmann, Ming Tang, Robert Geffers, Adam R. Wende, Mark P. Kühnel, Danny D. Jonigk, Georg Hansmann, Kai C. Wollert, E. Dale Abel, Stavros G. Drakos, Johann Bauersachs, Christian Riehle
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)
Background Alveolar hypoxia is protective in the context of cardiovascular and ischemic heart disease; however, the underlying mechanisms are incompletely understood. The present study sought to test the hypothesis that hypoxia is cardioprotective in
Externí odkaz:
https://doaj.org/article/faab23b5566643d4bb708c9cafa2f8de
Autor:
Ali Ghasemzadeh, Eric T. Wendt, Brendan Dolan, Juliana Craig, Glenn O. Allen, E. Jason Abel, Daniel D. Shapiro
Publikováno v:
Frontiers in Urology, Vol 3 (2023)
ObjectiveTo describe the treatment and outcomes of patients who are medically immunosuppressed due to prior organ transplantation or autoimmune disease with clinical T1 renal cell carcinoma (cT1).MethodsAn institutional database of patients treated f
Externí odkaz:
https://doaj.org/article/289fcbfcce6948e39f0a1bfb18ca804f
Autor:
Daniel D. Shapiro, Jose A. Karam, Logan Zemp, Viraj A. Master, Wade J. Sexton, Ali Ghasemzadeh, Benjamin N. Schmeusser, Facundo Davaro, Taylor Peak, Dattatraya Patil, Surena Matin, Philippe E. Spiess, E. Jason Abel
Publikováno v:
European Urology Open Science, Vol 50, Iss , Pp 43-46 (2023)
Patients with metastatic renal cell cancer (mRCC) who respond to upfront immune checkpoint inhibitor (ICI) combination therapies may be treated with cytoreductive nephrectomy (CN) to remove radiographically viable primary tumors. Early data for post-
Externí odkaz:
https://doaj.org/article/1e2ed9e25a3348a2bc31c993f9a5fb19
Autor:
Dong-Min Yu, Jiawei Zhao, Eunice E. Lee, Dohun Kim, Ruchika Mahapatra, Elysha K. Rose, Zhiwei Zhou, Calvin Hosler, Abdullah El Kurdi, Jun-Yong Choe, E. Dale Abel, Gerta Hoxhaj, Kenneth D. Westover, Raymond J. Cho, Jeffrey B. Cheng, Richard C. Wang
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
The facilitative GLUT1 and GLUT3 hexose transporters are expressed abundantly in macrophages, but whether they have distinct functions remains unclear. We confirmed that GLUT1 expression increased after M1 polarization stimuli and found that GLUT3 ex
Externí odkaz:
https://doaj.org/article/9c866e5d91dc452ebe9f5a92286a3c61
Autor:
Jayashree Jena, Luis Miguel García-Peña, Eric T Weatherford, Alex Marti, Sarah H Bjorkman, Kevin Kato, Jivan Koneru, Jason H Chen, Randy J Seeley, E Dale Abel, Renata O Pereira
Publikováno v:
eLife, Vol 12 (2023)
We previously reported that mice lacking the protein optic atrophy 1 (OPA1 BKO) in brown adipose tissue (BAT) display induction of the activating transcription factor 4 (ATF4), which promotes fibroblast growth factor 21 (FGF21) secretion as a batokin
Externí odkaz:
https://doaj.org/article/3aa1c08765f443d7bce9a2543a5753ec
Publikováno v:
Société Internationale d’Urologie Journal, Vol 3, Iss 6, Pp 451-463 (2022)
Renal cell carcinoma (RCC) has a natural tendency to invade the venous system with formation of a venous tumor thrombus in the renal vein, which can extend proximally into the inferior vena cava (IVC) and in some cases into the right atrium. The pres
Externí odkaz:
https://doaj.org/article/2e6a46b89e4147c0a1fc6fdb048aa947
Autor:
Moon Hee Lee, Kyung Sung, David Beebe, Wei Huang, Dan Shapiro, Shigeki Miyamoto, E. Jason Abel
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-9 (2022)
Abstract While an important role for the SUMO protease SENP1 is recognized in multiple solid cancers, its role in renal cell carcinoma (RCC) pathogenesis, particularly the most dominant subtype, clear cell RCC (ccRCC), is poorly understood. Here we s
Externí odkaz:
https://doaj.org/article/5ee96a81e3a44b89bac3dc2f5661c0ee