Zobrazeno 1 - 10
of 644
pro vyhledávání: '"E Phelan"'
Autor:
Siddharth Sanjay Pruthi, Nina Billows, Joseph Thorpe, Susana Campino, Jody E. Phelan, Fady Mohareb, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Tuberculosis disease (TB), caused by Mycobacterium tuberculosis (Mtb), is a major global public health problem, resulting in > 1 million deaths each year. Drug resistance (DR), including the multi-drug form (MDR-TB), is challenging control o
Externí odkaz:
https://doaj.org/article/27a3c6e1720f4a54b7adacb845e47a61
Autor:
Linfeng Wang, Dodge R. Lim, Jody E. Phelan, Lorenzo T. Reyes, Alma G. Palparan, Maria Guileane C. Sanchez, Louella Abigail A. Asuncion, Ma. Angelica A. Tujan, Inez Andrea P. Medado, Chona Mae A. Daga, Jo-Hannah S. Llames, Satoshi Mitarai, Yoshiro Murase, Yuta Morishige, Concepcion F. Ang, John Carlo M. Malabad, Jaime C. Montoya, Julius C. Hafalla, Susana Campino, Martin L. Hibberd, Cecilia G. Ama, Ramon P. Basilio, Eva Maria Cutiongoco-De La Paz, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The Philippines is a high-incidence country for tuberculosis, with the increasing prevalence of multi- (MDR-TB) and extensively-drug (XDR-TB) resistant Mycobacterium tuberculosis strains posing difficulties to disease control. Understanding
Externí odkaz:
https://doaj.org/article/234effea225840b6b03a67d753f81d1b
Autor:
Joseph Thorpe, Waritta Sawaengdee, Daniel Ward, Monica Campos, Nuanjun Wichukchinda, Boonchai Chaiyasirinroje, Aungkana Thanraka, Jaluporn Chumpol, Jody E. Phelan, Susana Campino, Surakameth Mahasirimongkol, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Whole genome sequencing (WGS) of Mycobacterium tuberculosis offers valuable insights for tuberculosis (TB) control. High throughput platforms like Illumina and Oxford Nanopore Technology (ONT) are increasingly used globally, although ONT is
Externí odkaz:
https://doaj.org/article/54126d1fc67a402d9b25239b32a04019
Autor:
Christophe Guyeux, Gaetan Senelle, Adrien Le Meur, Philip Supply, Cyril Gaudin, Jody E. Phelan, Taane G Clark, Leen Rigouts, Bouke de Jong, Christophe Sola, Guislaine Refrégier
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 3, Pp 560-563 (2024)
Analysis of genome sequencing data from >100,000 genomes of Mycobacterium tuberculosis complex using TB-Annotator software revealed a previously unknown lineage, proposed name L10, in central Africa. Phylogenetic reconstruction suggests L10 could rep
Externí odkaz:
https://doaj.org/article/d09a336b2efc4edf9d42a226f05ad04f
Autor:
Matthew Higgins, Emilia Manko, Daniel Ward, Jody E. Phelan, Debbie Nolder, Colin J. Sutherland, Taane G. Clark, Susana Campino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Despite Plasmodium ovale curtisi (Poc) and wallikeri (Pow) being important human-infecting malaria parasites that are widespread across Africa and Asia, little is known about their genome diversity. Morphologically identical, Poc and Pow are
Externí odkaz:
https://doaj.org/article/ffa566501b0a4bc5bfecf53666e0e269
Autor:
Jody E. Phelan, Anna Turkiewicz, Emilia Manko, Joseph Thorpe, Leen N. Vanheer, Marga van de Vegte-Bolmer, Nguyen Thi Hong Ngoc, Nguyen Thi Huong Binh, Nguyen Quang Thieu, Jesse Gitaka, Debbie Nolder, Khalid B. Beshir, Jamille G. Dombrowski, Silvia Maria Di Santi, Teun Bousema, Colin J. Sutherland, Susana Campino, Taane G. Clark
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Malaria continues to be a major threat to global public health. Whole genome sequencing (WGS) of the underlying Plasmodium parasites has provided insights into the genomic epidemiology of malaria. Genome sequencing is rapidly gain
Externí odkaz:
https://doaj.org/article/7560b9c5001943e9bf5a2232b2b917ca
Autor:
Holly Acford-Palmer, Monica Campos, Janvier Bandibabone, Sévérin N’Do, Chimanuka Bantuzeko, Bertin Zawadi, Thomas Walker, Jody E. Phelan, Louisa A. Messenger, Taane G. Clark, Susana Campino
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Vector control strategies have been successful in reducing the number of malaria cases and deaths globally, but the spread of insecticide resistance represents a significant threat to disease control. Insecticide resistance has been reported
Externí odkaz:
https://doaj.org/article/1a838087c29d4628853c4f8af7af7fd3
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Flaviviruses are a diverse group of RNA viruses, which include the etiological agents of Zika, dengue and yellow fever that are transmitted by mosquitoes. Flaviviruses do not encode reverse transcriptase and cannot reverse transcribe into DN
Externí odkaz:
https://doaj.org/article/29ccbb426b7c4f3e9d0b959c61e6859a
Autor:
Ashley Osborne, Jody E. Phelan, Leen N. Vanheer, Alphaxard Manjurano, Jesse Gitaka, Christopher J. Drakeley, Akira Kaneko, Kiyoshi Kita, Susana Campino, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Malaria has exhibited the strongest known selective pressure on the human genome in recent history and is the evolutionary driving force behind genetic conditions, such as sickle-cell disease, glucose-6-phosphatase deficiency, and some other
Externí odkaz:
https://doaj.org/article/a16d472dd2904e089c3a233382b7648b
Autor:
Ashley Osborne, Jody E. Phelan, Akira Kaneko, Wataru Kagaya, Chim Chan, Mtakai Ngara, James Kongere, Kiyoshi Kita, Jesse Gitaka, Susana Campino, Taane G. Clark
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Malaria control initiatives require rapid and reliable methods for the detection and monitoring of molecular markers associated with antimalarial drug resistance in Plasmodium falciparum parasites. Ngodhe island, Kenya, presents a unique mal
Externí odkaz:
https://doaj.org/article/66339eca5adf4207b3bef237ef38de6b